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Neurodevelopment and Mood Stabilizers
Current Molecular Medicine, 2003Mood disorders and schizophrenia share a number of common properties, including: genetic susceptibility; differences in brain structure and drug based therapy. Some genetic loci may even confer susceptibility for bipolar mood disorder and schizophrenia, and some atypical antipsychotic drugs are used as mood stabilizers.
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Histone Acetylation in Neurodevelopment
Current Pharmaceutical Design, 2013Post-translational modification of histones is a primary mechanism through which epigenetic regulation of DNA transcription does occur. Among these modifications, regulation of histone acetylation state is an important tool to influence gene expression.
Antonio, Contestabile, Silvia, Sintoni
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Thyroid hormones and neurodevelopment
Clinical Endocrinology, 1999BACKGROUND Maternal thyroid function during early pregnancy is an important determinant of early fetal brain development because the fetal thyroid is unable to produce any T4 before 12-14 weeks' gestation. Overt maternal hypothyroidism as seen in severe iodine-deficient areas is associated with severely impaired neurological development of the ...
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Impact of prematurity on neurodevelopment
2020The consequences of prematurity on brain functional development are numerous and diverse, and impact all brain functions at different levels. Prematurity occurs between 22 and 36 weeks of gestation. This period is marked by extreme dynamics in the physiologic maturation, structural, and functional processes.
Wallois, Fabrice +2 more
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2012
AbstractThis chapter discusses neural induction, organogenesis of the central nervous system, histogenesis of the spinal cord, histogenesis of the brainstem and cerebellum, histogenesis of the cerebral cortex, hemispheric shape and the formation of gyri, and genetic factors during development.
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AbstractThis chapter discusses neural induction, organogenesis of the central nervous system, histogenesis of the spinal cord, histogenesis of the brainstem and cerebellum, histogenesis of the cerebral cortex, hemispheric shape and the formation of gyri, and genetic factors during development.
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Pesticides and child neurodevelopment
Current Opinion in Pediatrics, 2008This review summarizes the recent research on pesticide exposure and child neurobehavioral development with a focus on in-utero exposure to organochlorine and organophosphate pesticides.Recent studies on in-utero exposure to the organochlorine pesticide dichlorodiphenyltrichloroethane and its breakdown product, dichlorodiphenyldichloroethene, indicate ...
Lisa G, Rosas, Brenda, Eskenazi
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Debugging neurodevelopment disorders
Cell Host & MicrobeGut bacteria are thought to contribute to neurodevelopmental disorders, but whether they are causal or predictive of disease remains unclear. In a prospective longitudinal study of thousands of children, Ahrens et al. generate evidence for the role of the gut microbiome in neurodevelopmental disorders while highlighting important open questions.
Jennie Sotelo-Orozco, Diana H. Taft
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Fatty Acids and Neurodevelopment
Journal of Pediatric Gastroenterology and Nutrition, 2008ABSTRACTKnowledge of the importance of docosahexaenoic acid (DHA), arachidonic acid (AA), and long‐chain polyunsaturated fatty acids (LCPUFAs) in neurodevelopment was originally obtained from animal studies. These fatty acids are rapidly accreted in brain during the first postnatal year in animal and human infants, and they are found in high ...
J, Belkind-Gerson +4 more
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The Neurodevelopment of the Brain
2023The pleasure pathway is a form of the limbic part of the brain that is responsible for behaviors. The brain is a very interesting phenomenon. It is comprised of various parts that consist of neurotransmitters (serotonin, dopamine, and norepinephrine, just to name a few).
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Nutrients, neurodevelopment, and mood
Current Psychiatry Reports, 2004Human neurodevelopment is the result of genetic and environmental interactions. This paper examines the role of prenatal nutrition relative to psychiatric disorders and explores the relationship among nutrients, mood changes, and mood disorders. Epidemiologic studies have found that adults who were born with a normal, yet low birth weight have an ...
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