Results 1 to 10 of about 128,632 (290)
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder [PDF]
Annals of Clinical and Translational NeurologyObjectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood.
Sam G. Norwitz +3 more
doaj +2 more sources
Frontiers in PsychiatryAutism Spectrum Disorder (ASD), characterized by socio-communicative abnormalities and restricted, repetitive, and stereotyped behaviors, is part of Neurodevelopmental Disorders (NDDs), a diagnostic category distinctly in accordance with the Diagnostic ...
Silvia Guerrera +10 more
doaj +3 more sources
SLC6A1 Neurodevelopmental Disorder: A Case Report [PDF]
BJPsych OpenAims: Solute Carrier Family 6 member 1 (SLC6A1) genetic mutations are rare and mostly reported in the paediatric population. Few reports on adult cases have been mentioned in the literature.
Nikita Pillay +2 more
doaj +2 more sources
Bimodal fibrosis in a novel mouse model of bleomycin-induced usual interstitial pneumonia
Life Science Alliance, 2022 A novel mouse model of induced-usual interstitial pneumonia shows bimodal fibrosis with honeycombing, similar to chronic lung disease seen with idiopathic pulmonary fibrosis.
Yoko Miura +3 more
doaj +1 more source
eLife, 2023 Expressions of voltage-gated sodium channels Nav1.1 and Nav1.2, encoded by SCN1A and SCN2A genes, respectively, have been reported to be mutually exclusive in most brain regions.
Tetsushi Yamagata +11 more
doaj +1 more source
ERJ Open Research, 2021 Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is relevant for the prognosis in patients with RA. Nintedanib, which inhibits both receptor and non-receptor type tyrosine kinases, is an antifibrotic drug for the treatment of ...
Yoko Miura +3 more
doaj +1 more source
Pathophysiological conditions induced by SARS-CoV-2 infection reduce ACE2 expression in the lung
Frontiers in Immunology, 2022 SARS-CoV-2 infection causes a variety of physiological responses in the lung, and understanding how the expression of SARS-CoV-2 receptor, angiotensin-converting enzyme 2 (ACE2), and its proteolytic activator, transmembrane serine protease 2 (TMPRSS2 ...
Yoko Miura +4 more
doaj +1 more source
Scientific Reports, 2022 CD80 interact with CD28 and CTLA-4 on antigen-presenting cells, and function in the co-stimulatory signaling that regulates T cell activity. CTLA-4-Ig is used to treat RA by blocking co-stimulatory signaling. Chronic inflammatory arthritis was induced in
Yoko Miura +3 more
doaj +1 more source
Language Outcomes of Children Born Very Preterm in Relation to Early Maternal Depression and Anxiety
Brain Sciences, 2023 Unaddressed maternal psychological distress within the first year postpartum is known to have numerous negative consequences on the child’s developmental outcomes, including language acquisition.
Sisan Cuervo +6 more
doaj +1 more source
Frontiers in Psychiatry, 2021 Schizophrenia before the age of 18 years is usually divided into two categories. Early-onset schizophrenia (EOS) presents between the ages of 13 and 17 years, whereas very-early-onset schizophrenia (VEOS) presents at or before the age of 12 years ...
Maria Pontillo +6 more
doaj +1 more source