Results 41 to 50 of about 5,323 (178)

Bilateral Ewing Sarcoma/Primitive Neuroectodermal Tumor of the Breast: A Very Rare Entity and Review of the Literature

Case Reports in Oncological Medicine, 2013
Peripheral primitive neuroectodermal tumors (PNET) are rare malignant tumors, affecting mostly children and adolescents and have been described in breast in eight case reports only.
N. Majid, M. Amrani, I. Ghissassi, M. El Cadi, M. El Bouzidi, M. El Kabous, A. Kherbach, H. Errihani   +7 more
doaj   +1 more source

Cervicomedullary intramedullary peripheral primitive neuroectodermal tumor with intratumoral bleed: Report of one case and review of literature

Journal of Craniovertebral Junction and Spine, 2016
Primitive neuroectodermal tumors (PNET) are highly malignant, yet relatively uncommon neoplasms of the central nervous system. Although a host of different parts of the nervous system can be affected, intramedullary location of PNET is extremely rare ...
Pradeep Sharma, Kuntal K Das, Anant Mehrotra, Arun K Srivastava, Rabi N Sahu, Awadhesh Jaiswal, Rakesh Pandey, Sanjay Behari, Kamlesh S Bhaisora, Jayesh Sardhara   +9 more
doaj   +1 more source

The Role of N6‐Methyladenosine Modification in Health and Disease

MedComm, Volume 7, Issue 6, June 2026.
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li, Yuanhai Sun, Wanfang Zheng, Lingqin Li, Yaqian Feng, Minyou Qi, Hanbing Li   +6 more
wiley   +1 more source

Peripheral primitive neuroectodermal tumor of the cervical spine

Surgical Neurology International, 2012
Primitive neuroectodermal tumor (PNET) is a malignant neoplasm that generally arises from bone and soft tissues, with predilection for young adults. This neural crest origin tumors share biologic and histologic features with Ewing's sarcoma (ES).We present a case of a 22-year-old woman with history of severe progressive neck pain, without radiation ...
Cabral, Gustavo A. P. S., Nunes, Cristian F., Melo, José O., Guimarães, Rodrigo D., Gonçalves, Mariangela B., Rodrigues, Ruy S., Correa, Jorge Luiz A., Teixeira, Orlando M., Klescoski, João, Lapenta, Mario A., Landeiro, José A.   +10 more
openaire   +3 more sources

A Systematic Review on the Role of Postoperative Radiotherapy in Pelvic Ewing Sarcoma

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Ewing Sarcoma of the pelvis has poorer outcomes than other anatomical sites, with complex anatomy often precluding resection with wide margins. The role of postoperative radiotherapy (RT) in improving outcomes remains undefined. A systematic review using Medline, Embase and Cochrane databases (1972–April 2024) evaluated postoperative RT's ...
Angela Hong, Tracy Lim, Helen Lo, Vivek A. Bhadri, Joanna Connor, Peter Grimison, Smaro Lazarakis, Jeremy Lewin, Jasmine Mar, Wayne Nicholls, Lisa Orme, Marianne B. Phillips, Stephen R. Thompson, Iain Ward, Mark Winstanley, Julie Cayrol, Natacha Omer   +16 more
wiley   +1 more source

Primitive neuroectodermal tumor presenting with superior vena cava syndrome

The Journal of Association of Chest Physicians, 2014
Peripheral primitive neuroectodermal tumor (PNET) of the chest wall is considered akin to Ewing′s sarcoma in terms of histology, immunohistology and cytogenetics. These tumors usually occur in children and young adults.
Vimal Kumar Nag, Devki Nandan, Abhishek Chatterjee, Minakshi Bhardwaj   +3 more
doaj   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Therapeutic approach of a pancreatic Ewing Sarcoma/PNET: case report and literature review

Brazilian Journal of Oncology, 2020
Peripheral primitive neuroectodermal tumors (pPNETs) are part of the Ewing sarcoma family. A few more than 30 cases of pPNETs originating on the pancreas have been reported in the consulted literature.
Rodrigo Nascimento Pinheiro, Fabiane Kellem Oliveira dos Santos Cesário, José Pablo Mata Mondragon, Fábio Daniel Barbosa da Silva, Renata Pereira Fontoura, José Donato de Sousa, Carlos Henrique de Aguiar Botelho   +6 more
doaj   +1 more source

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

MedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin, Yi Zhang, Ziling Zhou, Yaqi Zhang, Ting Yu, Rui Xu, Lin Xu, Jidong Zhang, Longze Zhang, Shan Yang, Xianyao Wang   +10 more
wiley   +1 more source

Induction of Brain Tumors by the Archetype Strain of Human Neurotropic JCPyV in a Transgenic Mouse Model

Viruses, 2021
JC Virus (JCPyV), a member of the Polyomaviridiæ family, is a human neurotropic virus with world-wide distribution. JCPyV is the established opportunistic infectious agent of progressive multifocal leukoencephalopathy, a fatal demyelinating disease ...
Luis Del Valle, Kamel Khalili
doaj   +1 more source