Results 101 to 110 of about 800,754 (297)

Prostate neuroendocrine carcinoma successfully treated with etoposide and cisplatin

IJU Case Reports
Introduction The frequency of neuroendocrine carcinoma of the prostate is low, accounting for approximately 1%–5% of all prostate cancers. Herein, we report the case of a patient who was diagnosed with prostate neuroendocrine carcinoma and successfully ...
Masanori Ishizaki, Masaru Hasumi, Kazumichi Muramatsu, Nobuaki Shimizu   +3 more
doaj   +1 more source

Next‐Generation CAR‐T Cell Therapy: From Modular Design to Clinical Expansion

Exploration, EarlyView.
Over the past decades, chimeric antigen receptor (CAR)‐T cell therapy has evolved from a linear engineering concept into a powerful yet constrained immunotherapy, limited by tumour microenvironment barriers, immune evasion, and manufacturing complexity.
Yuesong Bai, Jintao Qin, Zongjun Dai, Ran Yan, Yong Yang, Wenguang Wang   +5 more
wiley   +1 more source

Expression and Clinicopathologic Significance of Human Achaete-scute Homolog 1 in Pulmonary Neuroendocrine Tumors

Chinese Journal of Lung Cancer, 2010
Background and objective Human achaete-scute homolog 1 (hASH1) gene plays a critical role in development of the central nervous system, automatic nervous system, adrenal medullary chromaffin cells, thyroid C cells and pulmonary neuroendocrine cells.
Donghan ZHENG, Lijun WANG, Heyu HUANG, Rui LI, Zhiyong ZHONG, Fei LI, Daorong ZHANG   +6 more
doaj  

Successful treatment of large-cell neuroendocrine carcinoma of the prostate with pembrolizumab: a case report

Journal of Medical Case Reports
Background Large-cell neuroendocrine carcinoma of the prostate is an extremely rare disease and classified into two subtypes: de novo and treatment-induced large-cell neuroendocrine carcinoma that arises from adenocarcinoma via lineage plasticity in ...
Erika Yamashita, Shingo Ashida, Rie Yoshimura, Ryohei Iga, Yoshitaka Kurano, Shinkuro Yamamoto, Tsutomu Shimamoto, Hideo Fukuhara, Satoshi Fukata, Atsushi Kurabayashi, Takashi Karashima, Keiji Inoue   +11 more
doaj   +1 more source

Neuroendocrine differentiation and neuroendocrine morphology as two different patterns in large-cell bronchial carcinomas: outcome after complete resection

World Journal of Surgical Oncology, 2006
Background In 1999, large-cell neuroendocrine carcinoma of the lung was introduced by the World Health Organization (WHO) as a new tumor entity in the group of non-small cell, epithelial tumors, a differentiated classification of neuroendocrine tumors of
Passlick Bernward, Kayser Gian, Jungraithmayr Wolfgang, Eggeling Stephan   +3 more
doaj   +1 more source

Case Report: Large Cell Neuroendocrine Carcinoma of the Palatine Tonsil in a 76‐Year‐Old Patient

Head &Neck, EarlyView.
ABSTRACT Background Large cell neuroendocrine carcinoma (LCNEC) of the palatine tonsil is an extremely rare malignancy characterized by an aggressive clinical course and poor prognosis. Its nonspecific presentation often delays diagnosis. Methods We present the case of a 76‐year‐old female patient admitted to the Emergency Department with throat ...
Agnieszka Bugaj, Natalia Zagozda, Piotr Nogal, Gabriela Miczuga, Bartosz Czech, Jacek Banaszewski   +5 more
wiley   +1 more source

Surgical resection for clinical stage I high-grade neuroendocrine carcinoma of the lung

World Journal of Surgical Oncology, 2018
Background There are few reports about the factor influencing the prognosis of high-grade neuroendocrine carcinoma. In this study, we evaluated surgical outcome of clinical stage I high-grade neuroendocrine carcinoma.
Eisuke Mochizuki, Shun Matsuura, Kyohei Oishi, Koichi Miyashita, Koshiro Ichijyo, Syunya Furukawa, Miyuki Nagaoka, Shinichiro Mikura, Masaru Tsukui, Naoki Koshimizu, Shogo Sakurai, Kazuhiro Asada, Toshihiro Shirai   +12 more
doaj   +1 more source

Treatment Patterns and Survival Outcomes of Head and Neck Merkel Cell Carcinoma: An Age‐Stratified Analysis

Head &Neck, EarlyView.
ABSTRACT Background H&N Merkel cell carcinoma (MCC) mainly affects elderly patients, yet age‐stratified treatment patterns and outcomes data are scarce. Methods We analyzed 88 consecutive H&N MCC patients (2000–2022) by age (< 75 vs. ≥ 75 years). OS was estimated by Kaplan–Meier analysis and MCC‐specific death with competing‐risks methods (cause ...
Igor Vainer, Lior Strinkovsky, Eyal Fenig, Gideon Bachar   +3 more
wiley   +1 more source

NEUROENDOCRINE CARCINOMA OF THE UTERUS

, 2017
<p>Neuroendocrine carcinoma of the cervix and endometrium are very rare and aggressive tumours. The present case study is of a 52 year old female who was a known case of hypertension and diabetes mellitus and presented to Sir Ganga Ram Hospital ...
Kanika Chopra, Debasis Dutta, Rashmi Nigam, Kanika Jain   +3 more
core   +1 more source

Pretreatment Cachexia Index Is Associated With Severe Treatment Toxicity and Overall Survival in HPV‐Negative Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Introduction Cancer cachexia is characterized by skeletal muscle loss, poor nutrition, and systemic inflammation and is common in head and neck cancer. We evaluated whether the Cachexia Index (CXI) predicts treatment toxicity and survival in HPV‐negative HNSCC.
Gianluca Savoia, Michael P. Hier, Nader Sadeghi, Alex Mlynarek, Keith Richardson, Sabrina Daniela Silva Wurzba, Christina Tsien, George Shenouda, Khalil Sultanem, Nathaniel Bouganim, Khashayar Esfahani, Marco A. Mascarella   +11 more
wiley   +1 more source