Results 91 to 100 of about 800,754 (297)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Large Cell Neuroendocrine Carcinoma of Lung metastasizing to Jejunum – A rare presentation with review of Literature

Asian Journal of Medical Sciences, 2013
Large cell neuroendocrine carcinoma of lung is not one of the commoner varieties of neoplasia found in the lungs. There are around 100 cases in literature which suggest the metastasis of various kinds of lung carcinomas to gastro intestinal tract (GIT ...
Amit Gupta
doaj   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Clinical case of combined malignant neoplasm of the cervix: neuroendocrine carcinoma and squamous cell cancer

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Neuroendocrine carcinomas are rare and aggressive types of cervical tumors. Available literature contains limited descriptions of mixed carcinomas, and knowledge about this type of mixed carcinoma remains limited.
T. A. Garkusha, A. N. Zagrebel'nikova, V. N. Shelepova, F. V. Alyab'ev, N. V. Khludneva   +4 more
doaj   +1 more source

Exposure‐Response Analyses of Datopotamab Deruxtecan (Dato‐DXd), a TROP2‐Directed Antibody‐Drug Conjugate, in Advanced Non‐small Cell Lung Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Exposure‐response analyses supported a favorable benefit‐risk profile of Dato‐DXd at 6 mg/kg Q3W in patients with advanced nonsquamous NSCLC. Datopotamab deruxtecan (Dato‐DXd) is a trophoblast cell‐surface antigen‐2 (TROP2)‐directed antibody‐drug conjugate (ADC) that has demonstrated clinical activity in patients with NSCLC who have received prior ...
Ying Hong, Anna M. Mc Laughlin, Yuzhuo Pan, Sofia Friberg Hietala, Sophie Peigné, Michael Chargualaf, Zoey Tang, Diansong Zhou, Naoyuki Tajima, Malaz Abutarif, Tushar Garimella   +10 more
wiley   +1 more source

Representative section of neuroendocrine carcinoma component lymph node metastasis

, 2011
Copyright information:Taken from "Composite signet-ring cell/neuroendocrine carcinoma of the stomach with a metastatic neuroendocrine carcinoma component: a better prognosis entity"http://www.diagnosticpathology.org/content/2/1/43Diagnostic Pathology ...
Summer L Nugent (37927), Emily Bellavance (37930), John C Papadimitriou (37931), Nader Hanna (37932), Steven C Cunningham (37928), Borislav A Alexiev (37929)   +5 more
core   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Neuroendocrine Carcinoma of Urinary Bladder: Misdiagnosed Neoplasm

Online Journal of Health & Allied Sciences, 2020
Neuroendocrine carcinoma of the urinary bladder is an exceedingly rare pathology, comprising 0.35- 0.70% of all bladder cancers. The presenting symptoms and gross morphology are identical to conventional urothelial carcinoma, but the prognosis is much ...
Deepa Hunasghatta Chandrappa, Kanthilatha Pai   +1 more
doaj  

Primary neuroendocrine carcinoma of the thymus

Nigerian Medical Journal, 2013
Primary neuroendocrine tumors of the thymus, previously known as carcinoid tumors of the thymus, are unusual and rare tumors, and prognosis for these patients has been difficult to predict. We hereby report a case of primary neuroendocrine tumor of the thymus that had an aggressive and fatal course in spite of surgical resection and adjuvant ...
Gaude, Gajanan S, Hattiholi, Virupakshi, Malur, Prakash R, Hattiholi, Jyothi   +3 more
openaire   +4 more sources

Primary Pulmonary Mesenchymal Neoplasm With EWSR1::CREM Fusion: Cytologic Findings and Molecular Diagnosis

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Primary pulmonary mesenchymal neoplasms with EWSR1::CREM fusion are rare. These lesions are challenging to diagnose by morphology and immunohistochemistry alone. Case A 66‐year‐old woman (ex‐smoker) was found to have a 1.3‐cm right lower lobe lung nodule that had grown very slowly over a 9‐year period.
Priya Upadhyay, Sanjay Mukhopadhyay, Swikrity U. Baskota   +2 more
wiley   +1 more source