Results 181 to 190 of about 104,178 (284)

Functional analysis of AIP variants in a cohort of neuroendocrine neoplasms. [PDF]

Endocr Relat Cancer
Carranza-Zavala BR, Zuarth-Vázquez JM, López-Zelocualtecatl SM, Ramírez-Rentería C, Rodríguez-Torres M, Sosa-Eroza E, González-Virla B, Gamboa-Domínguez A, Reza-Albarrán AA, Hernández-Ramírez LC.   +9 more
europepmc   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Characterisation of adult patients with neuroendocrine neoplasms and their journey to diagnosis. [PDF]

BJC Rep
Ndlela B, Swann R, Lyratzopoulos G, Vernon S, Rous B, McPhail S, Rubin G.   +6 more
europepmc   +1 more source

Prognostic Role of Serum Neuron‐Specific Enolase at Baseline and its Early Dynamics in Metastatic Castration‐Resistant Prostate Cancer Treated With Androgen Receptor Signaling Inhibitors

The Prostate, EarlyView.
ABSTRACT Background Outcomes of metastatic castration‐resistant prostate cancer (mCRPC) treated with androgen receptor signaling inhibitors (ARSIs) vary widely and may not be fully reflected by PSA and standard clinicopathologic factors. We evaluated the prognostic value of serum neuron‐specific enolase (NSE) at baseline and early on‐treatment dynamics.
Ondřej Fiala, Michaela Tkadlecová, Zuzana Váchalová, Milan Hora, Jan Králíček, Petr Stránský Jr., Václav Liška, Matteo Santoni, Giuseppe Luigi Banna, Kristýna Pivovarčíková, Ondřej Topolčan, Jindřich Fínek   +11 more
wiley   +1 more source

Incidence and Survival of Gastro-Entero-Pancreatic Neuroendocrine Neoplasms in the Contemporary Era.

JAMA Netw Open
Hallet J, Meloche-Dumas L, Sarzo C, Court C, Armah J, Ding A, Chan WC, Singh S.   +7 more
europepmc   +1 more source

Novel concepts of cell-of origin in neuroendocrine neoplasms. [PDF]

Virchows Arch
Marinoni I, Avanthay S, Alcala N.
europepmc   +1 more source

In Silico Structure‐Guided Design of Peptide Candidates Targeting γ‐Secretase Subunit Assembly

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The γ‐secretase complex is a membrane‐embedded protease essential for intramembrane cleavage of substrates such as Notch receptors and the amyloid precursor protein (APP), processes central to cancer progression and Alzheimer's disease (AD) pathology.
Selcen Arı Yuka, Kübra Telli, Alper Yılmaz   +2 more
wiley   +1 more source

Connecting systemic inflammation to prognosis in neuroendocrine neoplasms: a biomarker-based approach. [PDF]

Front Med (Lausanne)
Iliesiu A, Gheorghişan-Gǎlǎțeanu AA, Țǎpoi DA, Lambrescu IM, Costache M, Tomescu LE, Derewicz D, Nimigean VR.   +7 more
europepmc   +1 more source

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha (Withania somnifera) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale, Jaising Salve, John Ademola, Jose Parraca, Deepak Langade   +4 more
wiley   +1 more source

Predicting the Unpredictable: AI-Driven Prognosis in Pancreatic Neuroendocrine Neoplasms. [PDF]

Cancers (Basel)
Merola E, Pirino E, Marcucci S, Chierichetti F, Michielan A, Bernardoni L, Gabbrielli A, Dore MP, Fanciulli G, Brolese A.   +9 more
europepmc   +1 more source