Results 131 to 140 of about 3,005,108 (342)

A phase II basket trial of dual anti‐CTLA‐4 and anti‐PD‐1 blockade in rare tumors (DART) SWOG S1609: durable responses and delayed pseudoprogression in small cell carcinoma of the ovary, hypercalcemic type cohort

Cancer Communications, EarlyView.
Abstract Background The combined use of anti‐programmed cell death protein 1 (PD‐1)/anti‐cytotoxic T‐lymphocyte associated protein 4 (CTLA‐4) checkpoint inhibitors has been effective in various cancer types. The Southwest Oncology Group (SWOG) Dual Anti‐CTLA‐4 and Anti‐PD‐1 Blockade in Rare Tumors (DART) S1609 study investigated ipilimumab and ...
Young Kwang Chae, Megan Othus, Sandip Pravin Patel, Raid Aljumaily, Khine Z. Win, Tanya Pejovic, Sajeve S. Thomas, William R. Robinson III, Hye Sung Kim, Liam Il‐Young Chung, Christine M. McLeod, Helen X. Chen, Elad Sharon, Howard Streicher, Christopher W. Ryan, Charles D. Blanke, Razelle Kurzrock   +16 more
wiley   +1 more source

Role of the microbiome in the development and treatment of gastric cancer: an overview of the biological and clinical landscape

ESMO Gastrointestinal Oncology
For decades, the stomach was considered a sterile organ, due to the acid environment. However, starting from the discovery of Helicobacter pylori, this concept has progressively refined. By damaging the hydrochloric acid-secreting glands, H.
C.A. Cella, D. Ciardiello, L. Gervaso, H. van Laarhoven, L. Nezi, C. Catozzi, F. Lordick, E. Smyth, S. de Pascale, L. Benini, C. Valenza, L. Guidi, U. Fumagalli Romario, N. Fazio   +13 more
doaj  

Subcellular Distribution of Somatostatin sst2A Receptors in Human Tumors of the Nervous and Neuroendocrine Systems: MembranousVersusIntracellular Location¹ [PDF]

, 2000
Jean Claude Reubi, Beatrice Waser, Qisheng Liu, J Laissue, Agnes Schönbrunn   +4 more
openalex   +1 more source

First‐line serplulimab plus chemotherapy in extensive‐stage small‐cell lung cancer: Updated results and biomarker analysis from the ASTRUM‐005 randomized clinical trial

Cancer Communications, EarlyView.
Abstract Background The ASTRUM‐005 study previously demonstrated a significant overall survival (OS) benefit with serplulimab (a programmed death 1 inhibitor) plus chemotherapy versus chemotherapy alone in previously untreated extensive‐stage small‐cell lung cancer (ES‐SCLC).
Ying Cheng, Shuang Zhang, Liang Han, Lin Wu, Jun Chen, Peiyan Zhao, Hongmei Sun, Guilan Wen, Yinghua Ji, Anastasia Zimina, Jianhua Shi, Zhijie Pan, Jinsheng Shi, Xicheng Wang, Yuansong Bai, Tamar Melkadze, Yueyin Pan, Xuhong Min, Maksym Viguro, Xingya Li, Yanqiu Zhao, Junquan Yang, Tamta Makharadze, Ekaterine Arkania, Haoyu Yu, Jing Li, Fang Yang, Xinyi Yang, Chen Ling, Qingyu Wang, Yongqiang Shan, Jun Zhu, the ASTRUM‐005 Study Group   +32 more
wiley   +1 more source

Radiation exposure and protection advice after [177Lu]Lu-DOTA-TATE therapy in China

EJNMMI Research
Background We conducted a study on radiation exposure in patients with gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) treated with [177Lu]Lu-DOTA-TATE in China for the first time, aiming to provide guidance and reference for radiation ...
Fei Liu, Panli Li, Junyan Xu, Jianping Zhang, Xiaoping Xu, Zhihao Chen, Ying Qiao, Yun Liang, Jie Chen, Shaoli Song   +9 more
doaj   +1 more source

Endoscopic ultrasound is highly accurate and directs management in patients with neuroendocrine tumors of the pancreas [PDF]

, 2000
Marcus Anderson
openalex   +1 more source

Trends in the Incidence, Prevalence, and Survival Outcomes in Patients With Neuroendocrine Tumors in the United States

JAMA Oncology, 2017
A. Dasari, Chan Shen, D. Halperin, Bo Zhao, Shouhao Zhou, Ying Xu, T. Shih, James C. Yao   +7 more
semanticscholar   +1 more source

Targeting Ubiquitin‐Specific Protease 7 with Novel 5‐Amino‐Pyrazole Inhibitors: Design, Synthesis, and Biological Evaluation

ChemMedChem, EarlyView.
Ubiquitin‐specific protease 7 (USP‐7) is a novel target for anticancer therapy. To further extend the structure–activity relationships of the previously USP‐7 inhibitor STIRUR‐41, a library of 5‐aminopyrazoles is reported. 1d shows a potency comparable to lead compound STIRUR‐41 and promising in silico and in vitro pharmacokinetic properties ...
Matteo Lusardi, Elva Morretta, Andrea Spallarossa, Maria Chiara Monti, Camillo Rosano, Erika Iervasi, Marco Ponassi, Matteo Mori, Fiorella Meneghetti, Chiara Brullo   +9 more
wiley   +1 more source

Site-Specific Epithelial-Mesenchymal Interactions in Digestive Neuroendocrine Tumors [PDF]

, 2000
Jérôme Dumortier, Christelle Ratineau, Jean–Yves Scoazec, Céline Pourreyron, Wena Anderson, Marie‐France Jacquier, Martine Blanc, Christine Bernard, Claire Bellaton, L Rémy, J.A. Chayvialle, Colette Roche   +11 more
openalex   +1 more source

Phase 3 Trial of 177Lu‐Dotatate for Midgut Neuroendocrine Tumors

New England Journal of Medicine, 2017
J. Strosberg, G. El-Haddad, E. Wolin, A. Hendifar, James C. Yao, B. Chasen, E. Mittra, P. Kunz, M. Kulke, H. Jacene, D. Bushnell, T. O'Dorisio, R. Baum, H. Kulkarni, M. Caplin, R. Lebtahi, T. Hobday, E. Delpassand, E. Van Cutsem, A. Benson, R. Srirajaskanthan, M. Pavel, J. Mora, J. Berlin, E. Grande, N. Reed, E. Seregni, K. Öberg, M. Sierra, P. Santoro, T. Thevenet, J. Erion, P. Ruszniewski, D. Kwekkeboom, E. Krenning   +34 more
semanticscholar   +1 more source