Results 181 to 190 of about 166,918 (340)

Metastatic jejunal neuroendocrine tumor to the breast: Case report and literature review [PDF]

open access: diamond, 2022
Gonzalo Fernández-Christlieb   +2 more
openalex   +1 more source

Increased incidence, survival, and registration quality of primary hepato‐pancreato‐biliary cancers in the Netherlands Cancer Registry

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Primary hepato‐pancreato‐biliary cancers have poor prognosis and their reporting often scores low on standard data quality indicators in population‐based cancer registries. This comprehensive evaluation of cases in the Netherlands Cancer Registry shows that both the incidence and survival rates of most primary hepato‐pancreato‐biliary ...
Lydia G. van der Geest   +13 more
wiley   +1 more source

Histopathological evaluation of dopamine receptor D2 expression in symptomatic gonadotroph pituitary neuroendocrine tumors: a case series including a rare metastatic case responsive to a dopamine agonist [PDF]

open access: hybrid
Ken Uekawa   +10 more
openalex   +1 more source

Long‐term impact of stressful life events on breast cancer risk: A 36‐year genetically informed prospective study in the Finnish Twin Cohort

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Breast cancer results from a combination of genetic and environmental causes, and the cumulative effect of stressful life events may be a contributing factor. Here, the authors analyzed data from cohort and twin‐pair studies including 36 years of follow‐up to find out how stressful life events affect breast cancer risk. They found that even
Elissar Azzi   +5 more
wiley   +1 more source

Type III gastric neuroendocrine tumor - a case report

open access: diamond, 2020
Teodora SPATARU, Lucian Negreanu
openalex   +1 more source

Novel therapeutic strategy targeting STMN1 using chlorambucil‐conjugated pyrrole–imidazole polyamide in small cell lung cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Small cell lung cancer (SCLC) is aggressive and difficult to treat but exhibits high levels of stathmin 1 (STMN1), a candidate therapeutic target. In this study, the authors synthesized a chlorambucil (Chb)‐conjugated pyrrole–imidazole polyamide (PIP) compound targeting the STMN1 promoter and DNA sequences and evaluated its efficacy in ...
Ryohei Yoshikawa   +23 more
wiley   +1 more source

KRAS‐G12C: The neglected biomarker to detect patients with MUTYH‐associated polyposis

open access: yesInternational Journal of Cancer, EarlyView.
What's New? MUTYH‐associated polyposis is an underdiagnosed recessive syndrome that predisposes individual to colorectal cancer and frequently displays KRAS‐G12C mutations. By analyzing a large cohort of colorectal cancer patients routinely tested for KRAS, the authors assessed whether KRAS‐G12C detection could serve as a pre‐screening tool for the ...
Ana Beatriz Deleame Medeiros   +9 more
wiley   +1 more source

A Dual Action of Everolimus in Ulcerative Colitis: Blocking CLEC4E‐Driven Inflammation and Remodeling the Gut Microbiota‐Metabolite Axis

open access: yesiMetaMed, EarlyView.
Graphical abstract of the major mechanisms of Everolimus in ulcerative colitis: Everolimus, a selective mTORC1 inhibitor, protects against ulcerative colitis through a dual mechanism. First, Eve directly suppresses CLEC4E/Syk/NF‐κB signaling, thereby reducing pro‐inflammatory cytokine production and preserving intestinal barrier integrity.
Jing Chen   +6 more
wiley   +1 more source

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