Results 231 to 240 of about 86,787 (249)

Oxytocin Enhances Demethylation Through TET Enzyme Expression in Neurons of Aged Mice: Oxytocin as a Potential Antiaging Peptide

Aging Cell, EarlyView.
DNA methylation, mitochondrial dysfunction, inflammation, and senescence interact to form a vicious cycle. Here we report that oxytocin interrupts this vicious cycle by increasing TET2 expression, inducing DNA demethylation in aged neurons and raising plasma oxytocin levels, decreasing systemic inflammation.
Yuko Maejima, Shoko Yokota, Megumi Yamachi, Shizu Hidema, Tomoyuki Ono, Shu Taira, Katsuhiko Nishimori, Heidi de Wet, Kenju Shimomura   +8 more
wiley   +1 more source

Cluster Analysis of VERDICT MRI for Cancer Tissue Characterization in Neuroendocrine Tumors. [PDF]

NMR Biomed
Lundholm L, Montelius M, Jalnefjord O, Schoultz E, Forssell-Aronsson E, Ljungberg M.   +5 more
europepmc   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Treatment of Pancreatic Neuroendocrine Tumors: Beyond Traditional Surgery and Targeted Therapy. [PDF]

J Clin Med
Bidani K, Marinovic AG, Moond V, Harne P, Broder A, Thosani N.   +5 more
europepmc   +1 more source

A luminal non‐coding RNA‐based genomic classifier confirms favourable outcomes in patients with clinically organ‐confined bladder cancer treated with radical cystectomy

BJU International, Volume 135, Issue 4, Page 648-656, April 2025.
Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.
Joep J. de Jong, James A. Proudfoot, Siamak Daneshmand, Robert S. Svatek, Vikram Narayan, Ewan A. Gibb, Elai Davicioni, Shreyas Joshi, Aaron Dahmen, Roger Li, Brant A. Inman, Paras Shah, Iftach Chaplin, Jonathan Wright, Yair Lotan   +14 more
wiley   +1 more source

Psychiatric and cognitive function in patients with serotonin producing neuroendocrine tumors. [PDF]

Transl Psychiatry
Luijendijk MJ, Tesselaar MET, van Rossum HH, van Faassen M, Korse CM, Verbeek WHM, Spruit JR, Scheelings PC, Hooghiemstra EH, Kema IP, Ruhé HG, Schagen SB, de Vries FE.   +12 more
europepmc   +1 more source

Transcriptome profiling of prostatic tumours from ENACT trial patients with or without enzalutamide

BJU International, EarlyView.
Objectives To evaluate the longitudinal transcriptomic changes that occurred over time in patients from the ENACT trial (ClinicalTrials.gov identifier: NCT02799745). ENACT evaluated patients with low‐ or intermediate‐risk prostate cancer, comparing the efficacy and safety of enzalutamide plus active surveillance (AS) to AS alone.
Nicole Handa, Neal D. Shore, Matthew R. Cooperberg, Elai Davicioni, Xin Zhao, Dina Elsouda, Yang Liu, James A. Proudfoot, Gaston Kuperman, David Russell, Kenneth K. Iwata, Edward M. Schaeffer, Ashley Ross   +12 more
wiley   +1 more source

Targeting DLL3: A New Weapon in Lung Neuroendocrine Tumors? [PDF]

JTO Clin Res Rep
Riudavets M, Planchard D.
europepmc   +1 more source

Everolimus in the Treatment of Neuroendocrine Tumors: Lights and Shadows. [PDF]

Biomedicines
Medici B, Caffari E, Maculan Y, Benatti S, Piacentini F, Dominici M, Gelsomino F.   +6 more
europepmc   +1 more source

Cauda equina neuroendocrine tumor: Report of a rare case

Asian Journal of Surgery
Guoyun Zhao, Zhengliang Fan, Qinghua Zou, Rong Yang   +3 more
doaj