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Tumor Markers in Neuroendocrine Tumors

Digestion, 2000
Most neuroendocrine tumors produce and secrete a multitude of peptide hormones and amines. Some of these substances cause a specific clinical syndrome: carcinoid, Zollinger-Ellison, hyperglycemic, glucagonoma and WDHA syndrome. Specific markers for these syndromes are basal and/or stimulated levels of urinary 5-HIAA, serum or plasma gastrin, insulin ...
K, Oberg, E T, Janson, B, Eriksson
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Neuroendocrine tumor of the rectum

The American Journal of Surgery, 2009
The authors report a case of a neuroendocrine tumor of the rectum. A 57-year-old man was revealed to have a large tumor of the rectum with invasion to the urinary bladder and seminal capsule. After resection, the tumor was revealed to be composed of neuroendocrine cells.
Koichi, Suyama   +11 more
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Imaging of Neuroendocrine Tumors

Expert Opinion on Medical Diagnostics, 2016
Neuroendocrine tumors (NETs) comprise a heterogeneous group of malignancies with a very variable clinical expression and progression. They present unique properties that are important to consider for radiological and nuclear imaging, such as APUD-characteristics (amine precursor uptake and dearboxylation), as well as the expression of somatostatin ...
Kjell, Öberg, Anders, Sundin
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Neuroendocrine Tumors of the Lung

Thoracic Surgery Clinics, 2021
Pulmonary neuroendocrine tumors (NETs) are relatively rare; however, their incidence is steadily increasing. They now comprise 1% to 2% of all lung cancers. Lung NETs are classified based on the World Health Organization classification into low-, intermediate-, and high-grade tumors.
Simran, Randhawa   +2 more
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RET and neuroendocrine tumors

Pituitary, 2006
The RET proto-oncogene encodes a receptor tyrosine kinase that is a main component of the signaling pathway activated by the glial cell line-derived neurotrophic factor family ligands. Gene targeting studies revealed that signaling through RET plays a crucial role in neuronal and renal organogenesis. It is well-known that germline mutations in RET lead
Yoshiki, Murakumo   +4 more
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Pancreatic neuroendocrine tumors

Current Opinion in Gastroenterology, 2019
Pancreatic neuroendocrine tumors (pNETs) are a rare, heterogeneous group of pancreatic neoplasms with a wide range of malignant potential. They may manifest as noninfiltrative, slow-growing tumors, locally invasive masses, or even swiftly metastasizing cancers.In recent years, because of the increasing amount of scientific literature available for ...
Perri G., Prakash L. R., Katz M. H. G.
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Chromogranin A and neuroendocrine tumors

Endocrinología y Nutrición (English Edition), 2013
Chromogranin A (CgA) is the most abundant granin in gastroenteropancreatic neuroendocrine tumors (GEP-NETs). As a tumor marker is moderately sensitive and nonspecific. Despite the limitations of testing methods, which require careful interpretation, especially in the case of gastrinomas, patients treated with somatostatin analogues, and poorly ...
José Ángel, Díaz Pérez   +1 more
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Pulmonary Neuroendocrine Tumors

Surgical Pathology Clinics, 2020
Pulmonary neuroendocrine tumors represent a morphologic spectrum of tumors from the well-differentiated typical carcinoid tumor, to the intermediate-grade atypical carcinoid tumor, to the high-grade neuroendocrine carcinomas composed of small-cell carcinoma and large-cell neuroendocrine carcinoma.
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Neuroendocrine tumors of the lung

Current Opinion in Oncology, 2008
The aim of this article is to answering different questions related to the treatment and prognosis of neuroendocrine lung tumors.In neuroendocrine lung tumors, regardless of the grade of tumoral malignancy, the general growth during the past years of the nodal involvement percentage detected in lung neuroendocrine tumors might be explained by accepting
Mariano, García-Yuste   +2 more
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Pancreatic Neuroendocrine Tumors

Surgical Pathology Clinics, 2016
Pancreatic neuroendocrine neoplasms include well-differentiated pancreatic neuroendocrine tumors (PanNETs) and neuroendocrine carcinomas (NECs) with well-differentiated PanNETs accounting for most cases. Other pancreatic primaries and metastatic carcinomas from other sites can mimic pancreatic neuroendocrine neoplasms.
Safia N, Salaria, Chanjuan, Shi
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