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Updates on medical treatment for neuroendocrine neoplasm [PDF]

open access: yesZhongguo aizheng zazhi, 2022
Neuroendocrine neoplasm (NEN) is a group of heterogeneous malignancies arising from neuroendocrine cells and peptidergic neurons. According to its cell differentiation, NEN can be divided into two distinct groups as well-differentiated neuroendocrine ...
LIANG Yun, JI Shunrong, YU Xianjun, CHEN Jie
doaj   +1 more source

Updates on precision medicine of pancreatic neuroendocrine tumor [PDF]

open access: yesZhongguo aizheng zazhi, 2023
Since the concept of precision medicine proposed in 2011, the treatment of solid tumors has entered era of precision medicine led by gene testing. As a rare tumor, the incidence rate of pancreatic neuroendocrine tumor (PanNET) is increasing gradually. In
GAO Heli, XU Jin, CHEN Jie, YU Xianjun
doaj   +1 more source

Clinical study of robot and laparoscopic minimally invasive surgery for well-differentiated pancreatic neuroendocrine tumors [PDF]

open access: yesZhongguo aizheng zazhi, 2022
Background and purpose: Pancreatic neuroendocrine tumor (pNET) is a rare tumor. At present, there is still a lack of large-scale clinical research data to summarize the clinical effect of minimally invasive technology in the treatment of pNET. This study
LIU Wensheng, JI Shunrong, ZHUO Qifeng, GAO Heli, SHI Yihua, XU Wenyan, LIU Mengqi, LI Zheng, YU Xianjun, CHEN Jie, XU Xiaowu
doaj   +1 more source

A real-life treatment cohort of pancreatic neuroendocrine tumors: High-grade increase in metastases confers poor survival

open access: yesFrontiers in Endocrinology, 2022
BackgroundTumor grade determined by the Ki67 index is the best prognostic factor for pancreatic neuroendocrine tumors (PanNETs). However, we often observe that the grade of metastases differs from that of their primary tumors.
Wu-Hu Zhang   +60 more
doaj   +1 more source

The Interplay of Four Main Pathways Recomposes Immune Landscape in Primary and Metastatic Gastroenteropancreatic Neuroendocrine Tumors

open access: yesFrontiers in Oncology, 2022
BackgroundThe four major pathways in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) including chromatin remodeling, DNA damage repair, activation of mTOR signaling, and telomere maintenance were mediated by some critical molecules and ...
Xin Lou   +51 more
doaj   +1 more source

MEN1 promotes ferroptosis by inhibiting mTOR-SCD1 axis in pancreatic neuroendocrine tumors

open access: yesActa Biochimica et Biophysica Sinica, 2022
Pancreatic neuroendocrine tumor (pNET) is the second most common malignant tumors of the pancreas. Multiple endocrine neoplasia 1 ( MEN1) is the most frequently mutated gene in pNETs and MEN1-encoded protein, menin, is a scaffold ...
Ye Zeng   +16 more
doaj   +1 more source

Multimodality imaging differentiation of pancreatic neuroendocrine tumors and solid pseudopapillary tumors with a nomogram model: A large single-center study

open access: yesFrontiers in Surgery, 2022
BackgroundPancreatic neuroendocrine tumors (pNETs) and solid pseudopapillary tumors (SPTs) are two of the most common pancreatic neoplasms with different treatment procedures.
Hai-Feng Hu   +37 more
doaj   +1 more source

Pancreatic neuroendocrine tumors

open access: yesIntractable & Rare Diseases Research, 2017
Pancreatic neuroendocrine neoplasms (pNENs) are a heterogeneous group of tumors including well differentiated pancreatic neuroendocrine tumors (pNETs) and neuroendocrine carcinomas (pNECs). The incidence of pNENs has increased over the past few decades.
Varas-Lorenzo, Modesto J.   +2 more
  +9 more sources

Hypovascular pancreatic neuroendocrine tumor with hepatic metastases: A case report and literature review

open access: yesRadiology Case Reports, 2021
Hypovascular pancreatic neuroendocrine tumors are uncommon pancreatic tumors and commonly misdiagnosed as pancreatic ductal adenocarcinoma or chronic mass-forming pancreatitis.
Ngo-Van Doan, MD   +7 more
doaj   +1 more source

Tuberous Sclerosis Complex With Multiple Organ Tumors: Case Report and Literature Review

open access: yesFrontiers in Oncology, 2022
Pancreatic neuroendocrine neoplasms (PNEN) are tumors that originate from neuroendocrine cells. Only about 1% patients are related to mutation of tuberous sclerosis complex gene. Here, we reported a rare case with involvement of multiple organs and space-
Xinhe Zhang   +15 more
doaj   +1 more source

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