Results 21 to 30 of about 26,912 (125)

A nationwide, multi‐institutional collaborative retrospective study of colorectal neuroendocrine tumors in Japan

Annals of Gastroenterological Surgery, 2021
Aim Neuroendocrine tumors (NETs) are one of the subtypes of neuroendocrine neoplasms and are defined as epithelial neoplasms with predominant neuroendocrine differentiation.
Tatsuro Yamaguchi, Keiichi Takahashi, Kazutaka Yamada, Hiroyuki Bando, Hideo Baba, Masaaki Ito, Kimihiko Funahashi, Hideki Ueno, Shin Fujita, Seiji Hasegawa, Yoshiharu Sakai, Kenichi Sugihara   +11 more
doaj   +1 more source

Plasma acylated and plasma unacylated ghrelin: useful new biomarkers in patients with neuroendocrine tumors?

Endocrine Connections, 2016
To date, the value of fasting plasma acylated ghrelin (AG) and unacylated ghrelin (UAG) as potential novel biomarkers in patients with neuroendocrine tumors (NETs) is unknown.The aims of this study are to (i) compare fasting AG and UAG levels between ...
Roxanne C S van Adrichem, Aart Jan van der Lely, Martin Huisman, Richard A Feelders, Patric J D Delhanty, Wouter W de Herder, Piet Kramer   +6 more
doaj   +1 more source

Serum tumor markers for detection of bone metastases in patients with lung neuroendocrine neoplasms”

Cancer Treatment and Research Communications, 2022
Background: Bone metastases (BM) are related to worse outcome in patients with neuroendocrine neoplasms (NENpts). Aim: Assess utility of serum tumor markers (STM) for detection of BM in lung NENpts.
Violetta Rosiek, Monika Wójcik-Giertuga, Beata Kos-Kudła   +2 more
doaj  

Epidemiologic trends of and factors associated with overall survival in patients with neuroendocrine tumors over the last two decades in the USA

Endocrine Connections, 2023
Background: Updated epidemiological data of neuroendocrine tumors are currently lacking. Thus, we performed epidemiological and survival analyses on a large cohort of patients with neuroendocrine tumors and developed a new nomogram to predict survival.
Peiwen Wu, Dongjie He, Hao Chang, Xiaozhi Zhang   +3 more
doaj   +1 more source

Immunotherapy in the neoadjuvant treatment of gastrointestinal tumors: is the time ripe?

Journal for ImmunoTherapy of Cancer
Immune checkpoint inhibitors (ICIs) revolutionized the management of mismatch repair-deficient (dMMR)/microsatellite instability-high (MSI-H) gastrointestinal (GI) cancers.
Davide Ciardiello, Francesca Spada, Nicola Fazio, Maria Giulia Zampino, Lorenzo Gervaso, Rivadavio Antunes Oliveira, Michele Borghesani, Lorenzo Guidi, Lavinia Benini, Laura Algeri, Chiara Alessandra Cella   +10 more
doaj   +1 more source

miR375-3p Distinguishes Low-Grade Neuroendocrine From Non-neuroendocrine Lung Tumors in FFPE Samples

Frontiers in Molecular Biosciences, 2020
Lung cancer is still one of the leading cause of death worldwide. The clinical variability of lung cancer is high and drives treatment decision. In this context, correct discrimination of pulmonary neuroendocrine tumors is still of critical relevance ...
Simone Detassis, Valerio del Vescovo, Margherita Grasso, Stefania Masella, Chiara Cantaloni, Luca Cima, Alberto Cavazza, Paolo Graziano, Giulio Rossi, Mattia Barbareschi, Leonardo Ricci, Leonardo Ricci, Michela Alessandra Denti   +12 more
doaj   +1 more source

An Intraoperative $β^-$ Detecting Probe For Radio-Guided Surgery in Tumour Resection [PDF]

, 2015
The development of the $\beta^-$ based radio-guided surgery aims to extend the technique to those tumours where surgery is the only possible treatment and the assessment of the resection would most profit from the low background around the lesion, as for brain tumours.
arxiv   +1 more source

MEN1 Deficiency‐Driven Activation of the β‐Catenin‐MGMT Axis Promotes Pancreatic Neuroendocrine Tumor Growth and Confers Temozolomide Resistance

Advanced Science
O6‐methylguanine DNA methyltransferase (MGMT) removes alkyl adducts from the guanine O6 position (O6‐MG) and repairs DNA damage. High MGMT expression results in poor response to temozolomide (TMZ).
Junfeng Xu, Xin Lou, Fei Wang, Wuhu Zhang, Xiaowu Xu, Zeng Ye, Qifeng Zhuo, Yan Wang, Desheng Jing, Guixiong Fan, Xuemin Chen, Yue Zhang, Chenjie Zhou, Jie Chen, Yi Qin, Xianjun Yu, Shunrong Ji   +16 more
doaj   +1 more source

Segmentation for Classification of Screening Pancreatic Neuroendocrine Tumors [PDF]

arXiv, 2020
This work presents comprehensive results to detect in the early stage the pancreatic neuroendocrine tumors (PNETs), a group of endocrine tumors arising in the pancreas, which are the second common type of pancreatic cancer, by checking the abdominal CT scans.
arxiv  

Learning Where to See: A Novel Attention Model for Automated Immunohistochemical Scoring [PDF]

, 2019
Estimating over-amplification of human epidermal growth factor receptor 2 (HER2) on invasive breast cancer (BC) is regarded as a significant predictive and prognostic marker. We propose a novel deep reinforcement learning (DRL) based model that treats immunohistochemical (IHC) scoring of HER2 as a sequential learning task.
arxiv   +1 more source