Results 81 to 90 of about 361,579 (250)

Synchronous Cystic Duct and Duodenal Neuroendocrine Tumours in a Patient with Neurofibromatosis 1: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Neurofibromatosis type 1 (NF1) is an autosomal dominant tumour-predisposition syndrome associated with various tumours. Amongst gastrointestinal tumours, Gastrointestinal Stromal Tumours (GISTs) and periampullary Neuroendocrine Tumours (NET) are most ...
Vishaalpalaniswamy Ramaswamy, Angeline Mary Samy, Swaminathan Kalyanasundaram, Selvaraj Thangasamy   +3 more
doaj   +1 more source

Neuroendocrine tumour metastasis to the orbit [PDF]

, 2019
Neuroendocrine neoplasms are tumours that usually arise in the gastrointestinal tract and the bronchopulmonary system. The orbit is a rare anatomical site for their metastases.
Kozubowska, Karolina; Medical University of Gdańsk, Gdańsk, Poland, Skorek, Andrzej; Medical University of Gdańsk, Gdańsk, Poland, Pęksa, Rafał; Medical University of Gdańsk, Gdańsk, Poland   +2 more
core   +1 more source

Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression. [PDF]

, 2020
Recent data suggest that Pancreatic Neuroendocrine Tumours (PanNETs) originate from α- or β-cells of the islets of Langerhans. The majority of PanNETs are non-functional and do not express cell-type specific hormones.
Dettmer, Matthias S, Maire, Renaud S, Di Domenico, Annunziata, Thirlwell, Chrissie, Vassella, Erik, Marinoni, Ilaria, Simillion, Cedric, Pipinikas, Christodoulos P, Perren, Aurel, Bräutigam, Konstantin   +9 more
core   +2 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Neuroendocrine tumour arising inside a tailgut cyst

, 2017
Tailgut cysts are rare benign retrorectal cysts arising from persistent remnants of an embryonic hindgut. Malignant transformation inside this lesion is very uncommon and occurrence of neuroendocrine tumours in this context is extremely rare.
Bermejo Marcos, E, A Alonso-Casado, Mora-Guzmán, I, Rodríguez Sánchez, A, I Mora-Guzmán, E Bermejo Marcos, Alonso-Casado, A, A Rodríguez Sánchez   +7 more
core   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

A neuroendocrine tumour of the sphenoid sinus and nasopharynx: a case report

B-ENT, 2010
A neuroendocrine tumour of the sphenoid sinus and nasopharynx: a case report. It is rare for neuroendocrine tumours to originate in the sphenoid sinus and the nasopharynx.
V. Vandist, F. Deridder, W. Waelput, P. M. Parizel, P. Van de Heyning, C. Van Laer   +5 more
doaj   +2 more sources

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

Advanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan, Chongchong Xu, Jiangmei Gao, Pu Wang, Qingling Wu, Ying Jin, Binyan Lu, Mu Li, Mingting Shao, Bihai Li, Zhenghui Su, Yijng Zhang, Jianhuan Chen, Haojie An, Mengyao Huang, Xiaoji Zhuang, Yuhui Shen, Fenglin Wang, Nana Xu, Yiyan Liu, Lei Tang, Xiuling Zhong, Minyan Zhong, Jiecong Chen, Zhenhuang Wang, Xingrong Luo, Sheng Liu, RuiFeng Liu, Ling Zhang, Junhua Rao   +29 more
wiley   +1 more source

Expression of parathyroid hormone-related protein in gastrointestinal malignancies. [PDF]

, 2006
Parathyroid hormone-related protein (PTHrP) is a peptide hormone which, when abundantly produced by certain tumours, and released into the systemic circulation, stimulates via an endocrine-like pathway, bone resorption and renal calcium reabsorption, by ...
McStay, M.K.G.
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