Results 41 to 50 of about 13,457 (177)
Objective: Sex steroids exert important biological functions within the CNS, but the underlying mechanisms are poorly understood. The contribution of circulating sex steroids to the levels in CNS tissue and cerebrospinal fluid (CSF) has been sparsely ...
Henrik Ryberg +7 more
doaj +1 more source
Abstract The supraoptic nucleus (SON) is a hypothalamic region essential for the orchestration of osmoregulation in mammals. We sought to understand how gene expression in the SON is orchestrated in a rodent species adapted for survival in arid desert conditions.
Benjamin T. Gillard +4 more
wiley +1 more source
Roles of traditional chinese medicine regulating neuroendocrinology on AD treatment
The incidence of sporadic Alzheimer’s disease (AD) is increasing in recent years. Studies have shown that in addition to some genetic abnormalities, the majority of AD patients has a history of long-term exposure to risk factors.
Chujun Deng +3 more
doaj +1 more source
Abstract Polybrominated diphenyl ethers (PBDEs) are neuroendocrine‐disrupting chemicals that produce adverse neurodevelopmental effects. PBDEs have been implicated as risk factors for autism spectrum disorder (ASD), which is characterized by abnormal psychosocial functioning and is commonly comorbid with cognitive deficits and sensory abnormalities ...
Elena V. Kozlova +28 more
wiley +1 more source
Abstract Chronic hyponatremia is associated with cognitive deficits, yet the underlying mechanisms remain elusive. A cerebral growth factor which is crucial for cognition and memory is brain‐derived neurotrophic factor (BDNF), but its role in hyponatremia has never been investigated.
Eszter Kustos‐Tóth +6 more
wiley +1 more source
The Year In Neuroendocrinology
At the "Year In Neuroendocrinology" session during the 2009 meeting of The Endocrine Society, I highlighted recent progress in three main areas of neuroendocrinology: neural mechanisms of action of estradiol, GnRH regulation, and epigenetics. In the area of neural mechanisms of action of estradiol, we have seen the list of estrogen receptors continue ...
openaire +3 more sources
Can acromegaly be controlled in all cases?
Abstract Acromegaly is a rare disease, due in most of the cases to a growth hormone (GH)‐secreting pituitary adenoma (PA), namely neuroendocrine tumour (PitNET). The treatment of patients with acromegaly is multimodal and multi‐step, including surgery, medical therapies, and radiotherapy.
Sabrina Chiloiro +14 more
wiley +1 more source
Androgen receptor alpha deficiency impacts aromatase expression in the female cichlid brain
Steroid hormones bind to specific receptors that act as transcription factors to modify gene expression in the brain to regulate physiological and behavioural processes.
Mariana S. Lopez, Beau A. Alward
doaj +1 more source
Social behavior is among the most complex and variable of traits. Despite its diversity, we know little about how genetic and developmental factors interact to shape natural variation in social behavior.
Steven M. Phelps +4 more
doaj +1 more source
Therapeutic potential of spexin in diabetic neuropathy: Insights from in vitro and in vivo models
Abstract The present study investigated the therapeutic potential of spexin (SPX) on both in vitro and in vivo models of diabetic neuropathy (DN). A total of 40 male BALB/c mice were randomly allocated into four experimental groups (n = 10 per group): a normoglycaemic control, an untreated DN group and two SPX treatment groups (DN+SPX‐12.5 and DN+SPX ...
Mehmet Refik Bahar +5 more
wiley +1 more source

