Results 91 to 100 of about 5,899 (197)

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Síndrome de moyamoya associada a neurofibromatose tipo I em paciente pediátrico [PDF]

, 2011
CONTEXT: Neurofibromatosis type 1 (NF-1) is the most prevalent autosomal dominant genetic disorder among humans. Moyamoya disease is a cerebral vasculopathy that is only rarely observed in association with NF-1, particularly in the pediatric age range ...
DARRIGO JÚNIOR, Luiz Guilherme, MACHADO, André de Aboim, SANTOS, Antonio Carlos dos, SCRIDELI, Carlos Alberto, TONE, Luiz Gonzaga, VALERA, Elvis Terci   +5 more
core   +1 more source

Healthcare professionals' perspectives on supporting individuals with NF1 during pregnancy and decision‐making processes

Journal of Genetic Counseling, Volume 34, Issue 6, December 2025.
Abstract Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic condition characterized by highly variable presentation, making reproductive decision‐making and pregnancy care particularly complex. While previous research has focused largely on clinical outcomes, little is known about how healthcare professionals (HCPs) provide care and ...
Gamze Kaplan, Debbie M. Smith, Ming Wai Wan, Emma Burkitt‐Wright, Shruti Garg   +4 more
wiley   +1 more source

Plexiform Neurofibroma of the Submandibular Salivary Gland in a Child

Canadian Journal of Gastroenterology, 2001
Plexiform neurofibromas in major salivary glands are rarely described. In the literature, most reported tumours have been present in the parotid gland region.
Jacqueline M Bourgeois, Jasim Radhi, Lisa Elden, Gerald Gill   +3 more
doaj   +1 more source

Morphological spectrum of peripheral nerve sheath tumors: A series of 126 cases

Indian Journal of Pathology and Microbiology, 2009
By convention, soft tissue tumors include the peripheral nerve sheath tumor (PNST) although they arise from neuroectoderm. PNSTs display a wide spectrum of morphology and biological behavior.
Gabhane Sushma, Kotwal Mrunamayi, Bobhate Sudhakar   +2 more
doaj  

Multidisciplinary Management of a Giant Plexiform Neurofibroma by Double Sequential Preoperative Embolization and Surgical Resection

Case Reports in Neurological Medicine, 2013
Plexiform neurofibromas are benign tumors originating from subcutaneous or visceral peripheral nerves, which are usually associated with neurofibromatosis type 1.
Roberto Vélez, Sergi Barrera-Ochoa, David Barastegui, Mercedes Pérez-Lafuente, Cleofe Romagosa, Manuel Pérez   +5 more
doaj   +1 more source

Diffuse plexiform neurofibroma [PDF]

Indian Journal of Surgery, 2010
S Sujith, Kumar, D Muthiah Selva, Kumar, R, Thirunavukuarasu   +2 more
openaire   +2 more sources

Giant Plexiform Neurofibroma

Journal of Surgical Dermatology, 2020
We report a rare case of giant plexiform neurofibroma in a patient affected by type-1 neurofibromatosis and we describe the correct surgical management of such lesions in order to avoid intra- and post-op blood loss related complications.
Michelangelo Giovanni Vestita, Rossella Elia, Giuseppe Giudice   +2 more
openaire   +3 more sources

Pelvic neurofibroma arising from prostate in a case of neurofibromatosis-1

Indian Journal of Urology, 2011
Pelvic neurofibroma is a rare condition and can be associated with neurofibromatosis-1 (NF-1). The diagnosis is primarily based on histopathology, though certain characteristic imaging features like the ′target sign′ on T2W MRI are highly suggestive of ...
Manisha Jana, Shivanand Gamanagatti, Rajeev Kumar, Sandeep Aggarwala   +3 more
doaj   +1 more source

Syndrome in question [PDF]

, 2016
Neurofibromatosis is extremely variable in its presentation. Segmental neurofibromatosis (SNF), which corresponds to NF-type 5 in the Riccardi classification, is a rare disorder. It may go unrecognized if few lesions are observed.
Carvalho, S., Horta, M., Oujo, E., Rosmaninho, A.   +3 more
core   +3 more sources