Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Plexiform Neurofibroma of the Submandibular Salivary Gland in a Child
Canadian Journal of Gastroenterology, 2001 Plexiform neurofibromas in major salivary glands are rarely described. In the literature, most reported tumours have been present in the parotid gland region.
Jacqueline M Bourgeois +3 more
doaj +1 more source
Morphological spectrum of peripheral nerve sheath tumors: A series of 126 cases
Indian Journal of Pathology and Microbiology, 2009 By convention, soft tissue tumors include the peripheral nerve sheath tumor (PNST) although they arise from neuroectoderm. PNSTs display a wide spectrum of morphology and biological behavior.
Gabhane Sushma +2 more
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Case Reports in Neurological Medicine, 2013 Plexiform neurofibromas are benign tumors originating from subcutaneous or visceral peripheral nerves, which are usually associated with neurofibromatosis type 1.
Roberto Vélez +5 more
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Pelvic neurofibroma arising from prostate in a case of neurofibromatosis-1
Indian Journal of Urology, 2011 Pelvic neurofibroma is a rare condition and can be associated with neurofibromatosis-1 (NF-1). The diagnosis is primarily based on histopathology, though certain characteristic imaging features like the ′target sign′ on T2W MRI are highly suggestive of ...
Manisha Jana +3 more
doaj +1 more source
A case of large diffuse cutaneous neurofibroma masquerading as plexiform variant: Diagnostic challenges [PDF]
Journal of Krishna Institute of Medical Sciences UniversityDiffuse Cutaneous Neurofibroma (DCN) is an infrequently encountered clinical entity that can be challenging to diagnose due to its variable clinical presentation, radiological findings, and histopathological features.
Shivani S Rao , Ranjana S Ranade
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Plexiform neurofibroma in the hepatic hilum associated with neurofibromatosis type 1: case report
Rare Tumors, 2009 We present an extremely rare case of plexiform neurofibroma involving the hepatic hilum. A 24-year old woman who had been diagnosed with neurofibromatosis type 1 was referred to our hospital for evaluation of an abdominal mass found on computed ...
Sojun Hoshimoto +8 more
doaj +1 more source
Facial plexiform neurofibroma in a 13-year-old girl with neurofibromatosis-1
Journal of Indian Academy of Oral Medicine and Radiology, 2012 Neurofbromatosis (NF) is an autosomal dominant disorder that affects the bone, the nervous system, soft tissue and the skin. NF is a neurocutaneous condition that can involve almost any organ system existing in two subtypes.
Satya Ranjan Misra +3 more
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Secondary Hip Osteoarthritis due to Neurofibroma Treated with Total Hip Replacement
Case Reports in Orthopedics, 2012 Background. Local plexiform neurofibroma can lead to deformity of the pelvis, valgus deformity of femoral neck, and joint capsule laxity. We report a case of secondary hip osteoarthritis with subluxation and coxa vara deformity resulting from an extra ...
Suksan Tangsataporn +5 more
doaj +1 more source
NEUROFIBROMATOSIS PLEXIFORME: ESTUDIO CON RM DE DOS CASOS CLÍNICOS Y REVISION DE LA LITERATURA
Revista Chilena de Radiología, 2007 La enfermedad de Von Recklinghausen o neurofibromatosis tipo 1 es una enfermedad genética caracterizada por lesiones cutáneas, malformaciones esqueléticas y algún grado de retraso mental.
M. Catalina Vial A +5 more
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