Results 81 to 90 of about 25,703 (229)

Solitary breast neurofibroma: imaging aspects

ecancermedicalscience, 2018
Neurofibromas are benign peripheral nerve sheath tumours, which are usually solitary and sporadic. Solitary neurofibromas of the breast are rare. The most common location of a breast neurofibroma is the nipple–areola complex.
A. Rotili, Federica De Maria, B. Di Venosa, M. Ghioni, M. Pizzamiglio, E. Cassano, Michela Moratti   +6 more
semanticscholar   +1 more source

Feasibility and Safety of Median Sternotomy Combined With Hemi‐Clamshell Incisions for the Resection of Extremely Large Tumors in the Thoracic Cavity: A Case Series

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT To evaluate the feasibility and safety of median sternotomy combined with hemi‐clamshell thoracotomy for resection of extremely large intrathoracic tumors. The perioperative data of three patients with large tumors in the thoracic cavity from January 2021 to December 2024 were collected and analyzed retrospectively, and median sternotomy ...
Xiaoyun Li, Mei Xu, Mingyu Fan, Xiaojun Tang   +3 more
wiley   +1 more source

Solitary neurofibroma of the inferior orbit: A rare occurrence

Muller Journal of Medical Sciences and Research, 2015
Solitary neurofibroma in the absence of neurofibromatosis is of rare occurrence and very few have been reported in the literature till now especially in the inferior orbit. A case of solitary neurofibroma of the inferior orbit is presented here.
V Sowmya, Nelly E. P. Nazareth, Ram Shenoy Basti, Nisha Marla   +3 more
doaj   +1 more source

Insertional mutagenesis identifies a STAT3/Arid1b/β-catenin pathway driving neurofibroma initiation

Cell Reports, 2016
Summary To identify genes and signaling pathways that initiate Neurofibromatosis type 1 (Nf1) neurofibroma, we used unbiased insertional mutagenesis screening, mouse models, and molecular analyses.
Jianqiang Wu, V. Keng, Deanna M. Patmore, Jed J. Kendall, Ami V. Patel, E. Jousma, Walter J. Jessen, Kwangmin Choi, Barbara R Tschida, Kevin A. T. Silverstein, Danhua Fan, Eric B. Schwartz, James R. Fuchs, Yuanshu Zou, Mi-Ok Kim, E. Dombi, D. Levy, Gang Huang, J. Cancelas, A. Stemmer-Rachamimov, R. Spinner, D. Largaespada, N. Ratner   +22 more
semanticscholar   +1 more source

DNA Hypomethylation Is Not Cell Intrinsically Toxic to Polycomb Repressive Complex 2 Deficient Malignant Peripheral Nerve Sheath Tumors

Genes, Chromosomes and Cancer, Volume 65, Issue 8, August 2026.
ABSTRACT Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas and the most common cause of disease‐associated death for neurofibromatosis type 1 (NF1) patients. In the context of NF1, MPNSTs develop from benign premalignant precursors and the transition to malignancy is typically accompanied by loss of the polycomb ...
Madilyn R. Stahl, Christopher M. Stehn, Zachary J. Seeman, Christopher Faulk, David A. Largaespada   +4 more
wiley   +1 more source

The role of nerve microenvironment for neurofibroma development

OncoTarget, 2016
Deregulation of RAS signaling in Neurofibromatosis type 1 (NF1) results in the development of multiple neurofibromas, complex tumor of the peripheral nerves with no effective medical treatment.
C. Liao, S. Pradhan, Zhiguo Chen, Amish J. Patel, R. C. Booker, L. Le   +5 more
semanticscholar   +1 more source

Selumetinib as a Target Therapy in Progressive Paediatric Low‐Grade Gliomas—Case Series (pLGG)

Journal of Paediatrics and Child Health, Volume 62, Issue 8, Page 1499-1508, August 2026.
ABSTRACT Background Optic pathway gliomas (OPGs) occur in 15%–20% of children with neurofibromatosis type 1 (NF1). While smaller gliomas may be only monitored, the current standard of care for symptomatic ones relies on chemotherapy, most commonly carboplatin and vincristine.
Laura Trapani, Giulia Gortani, Andrea Magnolato, Flora Maria Murru, Elisabetta Cattaruzzi, Laura Diplotti, Paola Michieletto, Silvia Giganti, Davide Zanon, Alessandra Maestro, Valentina Kiren, Egidio Barbi, Irene Bruno   +12 more
wiley   +1 more source

EGFR-Stat3 signalling in nerve glial cells modifies neurofibroma initiation

Oncogene, 2016
Neurofibromatosis type 1 (NF1) is an inherited disease in which affected patients are predisposed to develop benign Schwann cell (SC) tumours called neurofibromas. In the mouse, loss of Nf1 in the SC lineage causes neurofibroma formation.
Jianqiang Wu, W. Liu, W. Liu, Jon P. Williams, Jon P. Williams, Nancy Ratner   +5 more
semanticscholar   +1 more source

Chemokine receptor CCR3 is important for migration of mast cells in neurofibroma

Dermatologica Sinica, 2010
Background: Neurofibroma consists of abundant extracellular matrix and many types of cells, including Schwann cells (SCs), mast cells (MCs), fibroblasts and endothelial cells.
Wei-Chun Tai, Sin-Ting Wang, Chieh-Shan Wu, Tze-Yi Lin, Meng-Tse Wu   +4 more
doaj   +1 more source

Multiple Oral and Eyelid Nodules in a Pediatric Patient

Oral Diseases, EarlyView.
Caique Mariano Pedroso, Paulo Victor Mendes Penafort, Patrícia Vitor de Souza, Fernanda M. Pascon, Regina Maria Punppin‐Rontani, Beatriz Frolini Paulo Cherve, Rachel Marinho Robim, Regina Maria Holanda de Mendonça, Marcio Ajudarte Lopes, Pablo Agustin Vargas, Alan Roger Santos‐Silva   +10 more
wiley   +1 more source