Results 111 to 120 of about 28,521 (342)

Sciatic nerve fractional anisotropy and neurofilament light chain protein are related to sensorimotor deficit of the upper and lower limbs in patients with type 2 diabetes [PDF]

, 2023
Ζoltan Κender, Johann M. E. Jende, Felix T. Kurz, Dimitrios Tsilingiris, Lukas Schimpfle, Alba Sulaj, Ekaterina von Rauchhaupt, Hannelore Bartl, Christoph Mooshage, Jens Göpfert, Peter P. Nawroth, Stephan Herzig, Julia Szendroedi, Martin Bendszus, Stefan Kopf   +14 more
openalex   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Neurofilaments in CSF as diagnostic biomarkers in motor neuron disease: a meta-analysis

Frontiers in Aging Neuroscience, 2016
Objective: Neurofilaments in CSF are promising biomarkers which might help in the diagnosis of motor neuron disease (MND). We aim to assess the diagnostic value of neurofilaments in CSF for MND.Methods: Pubmed, Emabase and Web of Science were searched ...
Dawei Li, Dongchao Shen, Hongfei Tai, Liying Cui, Liying Cui   +4 more
doaj   +1 more source

The relevance of α-KLOTHO to the central nervous system: Some key questions [PDF]

, 2017
α-Klotho is well described as an anti-aging protein, with critical roles in kidney function as a transmembrane co-receptor for FGF23, and as a soluble factor in serum.
Berwick, Daniel Charles, Cararo-Lopes, Marina Minto, Kawamoto, Elisa Mitiko, Mazucanti, Caio Henrique Yokoyama, Scavone, Cristoforo   +4 more
core   +1 more source

Clinical stage and plasma neurofilament concentration in adults with Friedreich ataxia [PDF]

, 2023
Magnus Johnsson, Henrik Zetterberg, Kaj Blennow, Christopher Lindberg   +3 more
openalex   +1 more source

Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis

Advanced Science, EarlyView.
Using machine‐learning analyses in two independent multiple sclerosis cohorts, spinal cord atrophy and cortical degeneration emerged as key predictors of disability and progression independent of relapses. Deep gray matter damage further improved prediction, while serum biomarkers of brain damage provided complementary information, highlighting the ...
Alessandro Cagol, Pascal Benkert, Sabine Schaedelin, Mario Ocampo‐Pineda, Noemi Montobbio, Po‐Jui Lu, Batuhan Ayci, Antonia Wenger, Alfi Aran Shukur, Kornelius Kaim, Lester Melie‐Garcia, Matthias Weigel, Alessio Signori, Pasquale Calabrese, Ludwig Kappos, Maria Pia Sormani, Jens Kuhle, Cristina Granziera   +17 more
wiley   +1 more source

Some personal and historical notes on the utility of deep-etch electron microscopy for making cell structure/function correlations [PDF]

, 2014
This brief essay talks up the advantages of metal replicas for electron microscopy and explains why they are still the best way to image frozen cells in the electron microscope. Then it explains our approach to freezing, namely the Van Harreveld trick of
Heuser, John E
core   +2 more sources

A Conjugation Delivery System of Macrophages and Platelet Pharmacytes Promotes Regeneration After Spinal Cord Injury

Advanced Science, EarlyView.
A macrophage–platelet conjugation system (M‐P‐NPs@PPARγ) targets injure tissue to co‐deliver platelet mitochondria and PPARγ‐encoding NPs. This strategy boosts the macrophage energy supply and restores lipid homeostasis, leading to synergistically enhanced efferocytosis and tissue repair Abstract Mitochondrial dysfunction occurs in macrophages with ...
Haoli Wang, Hao Hu, Yijun Li, Lintao Hu, Chenhui Gu, Yiwei Zhu, Jing Huang, Na Li, Shuqi Jiang, Shouyan Zu, Jiachen Xu, Yining Wang, Ke Yang, Pengfei Chen, Liqing Shangguan, Yongcheng Wang, Shunwu Fan, Xianfeng Lin, Qingqing Wang   +18 more
wiley   +1 more source

Symposium on Frontiers of Molecular Neurobiology [PDF]

Membrane structure, synaptic transmission, and fibrous proteins of neurons ...

core   +1 more source

Axons Giving Rise to the Palisade Endings of Feline Extraocular Muscles Display Motor Features [PDF]

, 2013
Palisade endings are nerve specializations found in the extraocular muscles (EOMs) of mammals, including primates. They have long been postulated to be proprioceptors. It was recently demonstrated that palisade endings are cholinergic and that in monkeys
Davis López de Carrizosa, María América, Morado Díaz, Camilo José, Pastor Loro, Ángel Manuel, Rodríguez de la Cruz, Rosa María, Streicher, Johannes, Zimmermann, Lars   +5 more
core   +1 more source