Results 11 to 20 of about 28,521 (342)

Neurofilaments and Neurofilament Proteins in Health and Disease [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2017
SUMMARYNeurofilaments (NFs) are unique among tissue-specific classes of intermediate filaments (IFs) in being heteropolymers composed of four subunits (NF-L [neurofilament light]; NF-M [neurofilament middle]; NF-H [neurofilament heavy]; and α-internexin or peripherin), each having different domain structures and functions.
Aidong, Yuan   +3 more
openaire   +2 more sources

Immunomodulation stimulates the innervation of engineered tooth organ [PDF]

open access: yes, 2014
The sensory innervation of the dental mesenchyme is essential for tooth function and protection. Sensory innervation of the dental pulp is mediated by axons originating from the trigeminal ganglia and is strictly regulated in time. Teeth can develop from
Bécavin, Thibault   +5 more
core   +16 more sources

Neurofilament phosphoforms: Surrogate markers for axonal injury, degeneration and loss [PDF]

open access: yes, 2005
This review on the role of neurofilaments as surrogate markers for axonal degeneration in neurological diseases provides a brief background to protein synthesis, assembly, function and degeneration.
Petzold, A
core   +1 more source

Extra Axonal Neurofilaments Do Not Exacerbate Disease Caused by Mutant Cu,Zn Superoxide Dismutase

open access: yesNeurobiology of Disease, 2000
A recent report by T. L. Williamson et al. (1998, Proc. Natl. Acad. Sci. USA 95, 9631–9636) showed that disease caused by expression of mutant Cu,Zn superoxide dismutase (SOD1) in mice was slowed down by disruption of the neurofilament light (NF-L) gene.
Sébastien Couillard-Després   +2 more
doaj   +1 more source

Emerging Trends of Nanotechnology towards Picotechnology: Energy and Biomolecules [PDF]

open access: yes, 2010
In nature, metal oxide particles display their existence at the level of picomolecules in solution state and bioactive states in the body. We present evidence of picomolar behavior of molecules different than nanomolar behavior of particles.
Avdhesh Sharma   +2 more
core   +2 more sources

Time-related morphometric studies of neurofilaments in brain contusions

open access: yesFolia Neuropathologica, 2016
In forensic pathology age determination of injuries is of key importance. The purpose of the study was to analyze morphometrically changes in neurofilaments following the brain contusion and relate them to the length of the time of survival.
Mariusz Kobek   +5 more
doaj   +1 more source

Immunohistochemical Analysis of Differences of Toll-Like Receptor 2, Mast Cells, and Neurofilaments between Granulomatous Rosacea and Non-Granulomatous Rosacea

open access: yesIndian Journal of Dermatology, 2021
Background: Granulomatous rosacea is a distinct variant of rosacea because of its unique histopatholiogic findings. However, the pathogenesis of granulomatous rosacea has not yet been clearly demonstrated.
Ye Ji Jang   +4 more
doaj   +1 more source

Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]

open access: yes, 2015
Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa   +6 more
core   +2 more sources

NEUROFILAMENTS AS A POTENTIAL BIOMARKER IN PATIENTS WITH MULTIPLE SCLEROSIS: A REVIEW OF LITERATURE [PDF]

open access: yesJournal of IMAB
Background: Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central nervous system (CNS) characterized by demyelination, axonal damage and loss of neurons.
Magdalina Yanakieva   +3 more
doaj   +1 more source

CSF Heavy Neurofilament May Discriminate and Predict Motor Neuron Diseases with Upper Motor Neuron Involvement

open access: yesBiomedicines, 2021
Objective: To assess whether phosphorylated neurofilament heavy chain (pNfH) can discriminate different upper motor neuron (UMN) syndromes, namely, ALS, UMN-predominant ALS, primary lateral sclerosis (PLS) and hereditary spastic paraparesis (hSP) and to ...
Cecilia Simonini   +9 more
doaj   +1 more source

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