Exploring Brain and Ventricular Boundary Shift Integral Associations with Beta Amyloid and Neurofilament Light in Alzheimer’s Disease [PDF]
Negin Ashoori +10 more
openalex +1 more source
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen +11 more
wiley +1 more source
Diagnostic and Prognostic Value of Blood and Cerebrospinal Fluid Biomarkers in Amyotrophic Lateral Sclerosis: A Systematic Review and Meta-Analysis. [PDF]
Obara K +6 more
europepmc +1 more source
A multi-center study of neurofilament assay reliability and inter-laboratory variability
Elizabeth Gray +25 more
openalex +2 more sources
Abstract Aims This study investigated the long‐term effects of a multidomain intervention on cognition and metabolic control in patients with type 2 diabetes and mild cognitive impairment (MCI). Materials and methods Outpatients aged 70–85 years were randomized to an 18‐month multidomain intervention (comprising metabolic/vascular risk management ...
Taiki Sugimoto +16 more
wiley +1 more source
Targeted Proteomics upon Treatment with Tofersen Identifies Novel Response Markers for Superoxide Dismutase 1-Linked Amyotrophic Lateral Sclerosis. [PDF]
Steffke C +36 more
europepmc +1 more source
WONOEP XVII appraisal: The immunopathogenesis of epilepsy
Abstract There is a wealth of data indicating that the immune system plays an important role in seizure disorders. This includes autoimmune encephalitis, in which an immune response directed against neuronal antigens results in brain inflammation and subsequent seizure activity, as well as autoimmune‐associated epilepsy and neuroinflammatory changes ...
Nihan Çarçak +12 more
wiley +1 more source
Linking Cell Architecture to Mitochondrial Signaling in Neurodegeneration: The Role of Intermediate Filaments. [PDF]
Marzetti E +6 more
europepmc +1 more source
3′UTR variants of ALS‐linked RNAs modify subcellular and cellular phenotypes
Our study demonstrates that alternative 3′UTR variants of ALS‐linked transcripts modulate subcellular RNA localization and cytoskeletal architecture. NEFH 3′UTR‐Long promotes nuclear RNA clustering, while SOD1 3′UTR‐Long reduces filopodia formation. These results suggest that 3′UTRs, independent of coding sequences, can influence neuronal phenotypes ...
Melis Savasan‐Sogut +2 more
wiley +1 more source

