Results 301 to 310 of about 28,521 (342)

HCMV infection of terminally differentiated neurons disrupts microtubule organization, resulting in neurite retraction. [PDF]

Microbiol Spectr
Adelman JW, Sukowaty AT, Partridge KJ, Gawrys JE, Akins A, Terhune SS, Ebert AD.   +6 more
europepmc   +1 more source

Circulating Serum Cell-Free Mitochondrial DNA in Amyotrophic Lateral Sclerosis. [PDF]

Cells
Zanini G, Martinelli I, Sinigaglia G, Zucchi E, Banchelli F, Simonini C, Gianferrari G, Ghezzi A, Mandrioli J, Pinti M.   +9 more
europepmc   +1 more source

Neurofilament Light Chain Correlates with Stroke Severity and Clinical Outcome in Acute Cerebrovascular Stroke Patients. [PDF]

Cell Mol Neurobiol
Tony AA, Kholef EFM, Elgendy DB, Shoyb A.   +3 more
europepmc   +1 more source

Neurofilaments and Neurodegeneration

, 2023
openaire   +1 more source

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Neurofilament phosphorylation

Biochemistry and Cell Biology, 1995
Neurofilament proteins (NFPs) are highly phosphorylated molecules in the axonal compartment of the adult nervous system. The phosphorylation of NFP is considered an important determinant of filament caliber, plasticity, and stability. This process reflects the function of NFs during the lifetime of a neuron from differentiation in the embryo through ...
H C, Pant, , Veeranna
openaire   +2 more sources

Interference with kinesin‐based anterograde neurofilament axonal transport increases neurofilament‐neurofilament bundling

Cytoskeleton, 2012
AbstractNeurofilaments (NFs) associate with each other and with other cytoskeletal elements to form a lattice that supports the mature axon. Phosphorylation contributes to formation of this stationary population of NFs by fostering cation‐dependent interactions among NF sidearms.
Neethu, Sunil, Sangmook, Lee, Thomas B, Shea   +2 more
openaire   +2 more sources

Substructures of neurofilaments

Acta Neuropathologica, 1984
The results of this investigation indicate that neurofilaments of mammals (human and rabbit) are composed of four protofilaments each of which is formed of globular units connected by longitudinal bars. A cross-view of neurofilaments reveals the presence of four globular units, 20-25 A in diameter, connected by four transverse bars, 25-30 A in length ...
G Y, Wen, H M, Wisniewski
openaire   +2 more sources

C‐terminal neurofilament phosphorylation fosters neurofilament–neurofilament associations that compete with axonal transport

Cytoskeleton, 2010
AbstractNeurofilaments (NFs) associate with each other and with other cytoskeletal elements to form a lattice that supports the mature axon. Phosphorylation contributes to formation of this structure by fostering cation‐dependent interactions among NF sidearms. By inducing NF bundling, phosphorylation impedes their axonal transport.
Sangmook, Lee, Neethu, Sunil, Thomas B, Shea   +2 more
openaire   +2 more sources

Neurofilaments and neurological disease

BioEssays, 2003
AbstractNeurofilaments are one of the major components of the neuronal cytoskeleton and are responsible for maintaining the calibre of axons. They are modified by post‐translational changes that are regulated in complex fashions including by the interaction with neighbouring glial cells.
Al-Chalabi, A, Miller, C C J
openaire   +3 more sources