Results 81 to 90 of about 28,521 (342)

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung   +7 more
wiley   +1 more source

Serum neurofilament light chain levels at attack predict post-attack disability worsening and are mitigated by inebilizumab: analysis of four potential biomarkers in neuromyelitis optica spectrum disorder [PDF]

open access: hybrid, 2023
Orhan Aktaş   +17 more
openalex   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

Mechanisms of Axon Elongation Following CNS Injury: What Is Happening at the Axon Tip?

open access: yesFrontiers in Cellular Neuroscience, 2020
After an injury to the central nervous system (CNS), functional recovery is limited by the inability of severed axons to regenerate and form functional connections with appropriate target neurons beyond the injury.
William Rodemer   +4 more
doaj   +1 more source

Elasticity of Stiff Biopolymers

open access: yes, 2007
We present a statistical mechanical study of stiff polymers, motivated by experiments on actin filaments and the considerable current interest in polymer networks.
Abhijit Ghosh   +12 more
core   +1 more source

Trisomy 19 ependymoma, a newly recognized genetico-histological association, including clear cell ependymoma [PDF]

open access: yes, 2007
Ependymal tumors constitute a clinicopathologically heterogeneous group of brain tumors. They vary in regard to their age at first symptom, localization, morphology and prognosis. Genetic data also suggests heterogeneity.
Chapon, F   +11 more
core   +3 more sources

The CRL3 gigaxonin ubiquitin ligase–USP15 pathway governs the destruction of neurofilament proteins [PDF]

open access: green, 2023
Hyoung-Min Park   +6 more
openalex   +1 more source

Traumatic Microhemorrhages Are Not Synonymous With Axonal Injury

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.
Karinn Sytsma   +9 more
wiley   +1 more source

Neurodegenerative Biomarkers in Multiple Sclerosis: At the Interface Between Research and Clinical Practice

open access: yesDiagnostics
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurodegeneration within the central nervous system (CNS).
Alin Ciubotaru   +10 more
doaj   +1 more source

Plasma neurofilament light protein provides evidence of accelerated brain ageing in treatment-resistant schizophrenia [PDF]

open access: gold, 2023
Cassandra Wannan   +12 more
openalex   +1 more source

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