Results 81 to 90 of about 28,521 (342)
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
Serum neurofilament light chain levels at attack predict post-attack disability worsening and are mitigated by inebilizumab: analysis of four potential biomarkers in neuromyelitis optica spectrum disorder [PDF]
Orhan Aktaş +17 more
openalex +1 more source
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman +9 more
wiley +1 more source
Mechanisms of Axon Elongation Following CNS Injury: What Is Happening at the Axon Tip?
After an injury to the central nervous system (CNS), functional recovery is limited by the inability of severed axons to regenerate and form functional connections with appropriate target neurons beyond the injury.
William Rodemer +4 more
doaj +1 more source
Elasticity of Stiff Biopolymers
We present a statistical mechanical study of stiff polymers, motivated by experiments on actin filaments and the considerable current interest in polymer networks.
Abhijit Ghosh +12 more
core +1 more source
Trisomy 19 ependymoma, a newly recognized genetico-histological association, including clear cell ependymoma [PDF]
Ependymal tumors constitute a clinicopathologically heterogeneous group of brain tumors. They vary in regard to their age at first symptom, localization, morphology and prognosis. Genetic data also suggests heterogeneity.
Chapon, F +11 more
core +3 more sources
The CRL3 gigaxonin ubiquitin ligase–USP15 pathway governs the destruction of neurofilament proteins [PDF]
Hyoung-Min Park +6 more
openalex +1 more source
Traumatic Microhemorrhages Are Not Synonymous With Axonal Injury
ABSTRACT Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.
Karinn Sytsma +9 more
wiley +1 more source
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurodegeneration within the central nervous system (CNS).
Alin Ciubotaru +10 more
doaj +1 more source
Plasma neurofilament light protein provides evidence of accelerated brain ageing in treatment-resistant schizophrenia [PDF]
Cassandra Wannan +12 more
openalex +1 more source

