Results 291 to 300 of about 218,517 (358)

Sex-specific influences of APOEε4 genotype on hippocampal neurogenesis and progenitor cells in middle-aged rats. [PDF]

Biol Sex Differ
Lee BH, Cevizci M, Lieblich SE, Galea LAM.   +3 more
europepmc   +1 more source

Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat

, 2001
Kunlin Jin, Manabu Minami, Jing Lan, Xiao Mao, Sophie Batteur, Roger P. Simon, David A. Greenberg   +6 more
openalex   +1 more source

Neurogenesis by Progenitor Cells in the Ischemic Adult Rat Hippocampus

, 2001
Yoshiki Yagita, Kazuo Kitagawa, Toshiho Ohtsuki, Ken-ichiro Takasawa, Takaki Miyata, Hideyuki Okano, Masatsugu Hori, Masayasu Matsumoto   +7 more
openalex   +1 more source

Signaling Centers Drive Brachyury Dynamics and Lineage Commitment in mESC Aggregates

FASEB BioAdvances, EarlyView.
We used a mouse embryonic stem cell aggregate model to compare the use of Chiron and BMP4 signaling as pulses (applied to the whole aggregate) or signaling centers (applied to part of the aggregate). BMP4 as a pulse was shown to drive neural differentiation, with Chiron inhibiting this effect.
A. Rabeling, M. Goolam
wiley   +1 more source

Emerging approaches to bridging discovery science with clinical care in Alzheimer's disease. [PDF]

Neurotherapeutics
Sinha S, Gan L, Pieper AA.
europepmc   +1 more source

The evolution of sensitive periods beyond early ontogeny: Bridging theory and data

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Sensitive periods, in which experiences have a large impact on phenotypic development, are most common early in ontogeny. Yet, they may also occur at later ontogenetic stages, such as adolescence.
Nicole Walasek, Karthik Panchanathan, Willem E. Frankenhuis   +2 more
wiley   +1 more source

SR-FTIR Biomolecular Characterization of the Hippocampus: The Role of Tenascin C in Adult Murine Neurogenesis in the Subgranular Zone. [PDF]

Cells
Korenić M, Korenić A, Stamenković V, Dučić T, Andjus P.   +4 more
europepmc   +1 more source

Age‐Dependent Regulation of Hippocampal Inflammation by the Mitochondrial Translocator Protein in Mice

Aging Cell, EarlyView.
The role of mitochondrial translocator protein (TSPO) in hippocampal inflammation is age‐dependent, with TSPO deletion drastically exacerbating inflammation in aged mice, while dampening it in young mice. This TSPO–aging interaction was linked to NF‐kβ and interferon regulatory transcriptional networks. TSPO deletion exacerbated age‐dependent depletion
Kei Onn Lai, Jia Hui Wong, Nevin Tham, Lauren Fairley, Roshan Ratnakar Naik, Yulan Wang, Sarah R. Langley, Anna M. Barron   +7 more
wiley   +1 more source

Neuroinflammation-A Crucial Factor in the Pathophysiology of Depression-A Comprehensive Review. [PDF]

Biomolecules
Sălcudean A, Bodo CR, Popovici RA, Cozma MM, Păcurar M, Crăciun RE, Crisan AI, Enatescu VR, Marinescu I, Cimpian DM, Nan AG, Sasu AB, Anculia RC, Strete EG.   +13 more
europepmc   +1 more source

Aerobic Exercise Restores Hippocampal Neurogenesis and Cognitive Function by Decreasing Microglia Inflammasome Formation Through Irisin/NLRP3 Pathway

Aging Cell, EarlyView.
Exercise improved PD pathology and memory by reducing microglial inflammation, apoptosis, and the formation of the NLRP3 inflammasome via irisin signaling. Irisin administration partially replicated the beneficial effects of exercise on PD pathology.
Renqing Zhao, Xin Tian, Haocheng Xu, Yuanxin Wang, Junjie Lin, Bin Wang   +5 more
wiley   +1 more source