Results 321 to 330 of about 218,517 (358)

Mitonuclear Communication in Stem Cell Function

Cell Proliferation, EarlyView.
In this review, we highlight the critical functions of mitonuclear communication and its impact on mitochondrial proteostasis. Additionally, we examine how mitonuclear signalling influences stem cell function, offering new insights into cellular homeostasis, stem cell therapies, and the potential for lifespan extension.
Baozhou Peng, Yaning Wang, Hongbo Zhang
wiley   +1 more source

Detection of Mitotic Neuroblasts Provides Additional Evidence of Steady-State Neurogenesis in the Adult Small Intestinal Myenteric Plexus. [PDF]

eNeuro
Gorecki AM, Slosberg J, Hong SM, Seika P, Puttapaka SN, Migden B, Gulko A, Singh A, Zhang C, Gurumurthy R, Kulkarni S.   +10 more
europepmc   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via the FGF signalling pathway. [PDF]

Elife
Bose M, Talwar I, Suresh V, Mishra U, Biswas S, Yadav A, Suryavanshi ST, Hippenmeyer S, Tole S.   +8 more
europepmc   +1 more source

Human Midbrain Organoids Enriched With Dopaminergic Neurons for Long‐Term Functional Evaluation

Cell Proliferation, EarlyView.
We optimised a protocol that combines developmental patterning with mechanical cut to produce pint‐sized midbrain organoids, with diameters less than 300 μm, suitable for long‐term evaluation, along with a comprehensive functional assay system consisting of calcium transient assay, neurite extension assay, and multielectrode array assay. ABSTRACT Human
Xinyue Wang, Gaoying Sun, Mingming Tang, Da Li, Jianhuan Qi, Chuanyue Wang, Yukai Wang, Baoyang Hu   +7 more
wiley   +1 more source

Impaired olfactory bulb neurogenesis mediated by Notch1 contributes to olfactory dysfunction in mice chronically exposed to methamphetamine. [PDF]

Cell Biol Toxicol
Gu C, Wang Z, Luo W, Ling H, Cui X, Deng T, Li K, Huang W, Xie Q, Tao B, Qi X, Peng X, Ding J, Qiu P.   +13 more
europepmc   +1 more source

Urolithin A alleviates schizophrenic-like behaviors and cognitive impairment in rats through modulation of neuroinflammation, neurogenesis, and synaptic plasticity. [PDF]

Sci Rep
Huang Z, Ren Z, Wang S, Xiao L, Ling Y, Xie Y, Wang G, Zhou B.   +7 more
europepmc   +1 more source

A Rapid F0 CRISPR Screen in Zebrafish to Identify Regulator Genes of Neuronal Development in the Enteric Nervous System. [PDF]

Neurogastroenterol Motil
Davidson AE, Straquadine NRW, Cook SA, Liu CG, Nie C, Spaulding MC, Ganz J.   +6 more
europepmc   +1 more source

Neurogenesis and glial impairments in congenital hydrocephalus: insights from a BioGlue-induced fetal lamb model. [PDF]

Fluids Barriers CNS
Karakaya D, Lampe K, Encinas JL, Duru S, Peiro L, Oge HK, Sanchez-Margallo FM, Oria M, Peiro JL.   +8 more
europepmc   +1 more source