Results 11 to 20 of about 3,505 (170)

Botulinum Toxin in Neurogenic Detrusor Overactivity [PDF]

International Neurourology Journal, 2012
Purpose To evaluate the effects of botulinum toxin on urodynamic parameters and quality of life in patients with neurogenic detrusor overactivity. Methods Thirty four adult patients with spinal cord injury and detrusor overactivity were selected.
Carlos Arturo Levi D'Ancona, Rúiter Silva Ferreira, Mauricio Carneiro Rassi   +2 more
doaj   +3 more sources

Botulinum toxin injections for treating neurogenic detrusor overactivity [PDF]

Urology Research and Practice, 2019
Neurogenic detrusor overactivity (NDO) is a disorder that can cause high intravesical pressure, decreased capacity, decreased bladder compliance, and upper urinary system damage.
Ömer Bayrak, Erkan Sadioğlu, Rahmi Onur   +2 more
doaj   +3 more sources

OnabotulinumtoxinA for the treatment of neurogenic detrusor overactivity in children. [PDF]

Neurourol Urodyn, 2021
AbstractAimsThis study evaluated whether one (or more) of three doses of onabotulinumtoxinA were safe and effective to treat neurogenic detrusor overactivity (NDO) in children.MethodsThis was a 48‐week prospective, multicenter, randomized, double‐blind study in children (aged 5–17 years) with NDO and urinary incontinence (UI) receiving one ...
Austin PF, Franco I, Dobremez E, Kroll P, Titanji W, Geib T, Jenkins B, Hoebeke PB.   +7 more
europepmc   +4 more sources

Pharmacokinetics of solifenacin in pediatric populations with overactive bladder or neurogenic detrusor overactivity. [PDF]

Pharmacol Res Perspect, 2020
AbstractThe aim of this investigation was to characterize and compare the pharmacokinetics (PK) of the antimuscarinic drug solifenacin in pediatric patients with overactive bladder (OAB) or neurogenic detrusor overactivity (NDO) utilizing data from three phase III trials.
Tannenbaum S, den Adel M, Krauwinkel W, Meijer J, Hollestein-Havelaar A, Verheggen F, Newgreen D.   +6 more
europepmc   +5 more sources

Mechanism of Action of Botulinum Toxin A in Treatment of Functional Urological Disorders

Toxins, 2020
Intravesical botulinum toxin (BoNT) injection is effective in reducing urgency and urinary incontinence. It temporarily inhibits the detrusor muscle contraction by blocking the release of acetylcholine (Ach) from the preganglionic and postganglionic ...
Yu-Hua Lin, Bing-Juin Chiang, Chun-Hou Liao   +2 more
doaj   +1 more source

Intravesical therapy options for neurogenic detrusor overactivity [PDF]

Spinal Cord, 2004
Review article.Neuro-Urology, Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland.This review considers intravesical treatment options of neurogenic detrusor overactivity and discusses the underlying mechanism of action, clinical safety and efficacy, and the future trends.The available literature was reviewed using medline ...
Reitz A, Schurch B
openaire   +3 more sources

Prediction of autonomic dysreflexia during urodynamics: a prospective cohort study

BMC Medicine, 2018
Background Autonomic dysreflexia is a severe and potentially life-threatening condition in patients with spinal cord injury, as it can lead to myocardial ischemia, brain hemorrhage, or even death.
Matthias Walter, Stephanie C. Knüpfer, Jacquelyn J. Cragg, Lorenz Leitner, Marc P. Schneider, Ulrich Mehnert, Andrei V. Krassioukov, Martin Schubert, Armin Curt, Thomas M. Kessler   +9 more
doaj   +1 more source

Bladder diverticuli following injection of onabotulinum toxin A in a patient with multiple sclerosis and autosomal dominant polycystic kidney disease

Radiology Case Reports, 2018
Urinary incontinence due to neurogenic detrusor overactivity is common in patients with disorders of lower motor neurons controlling the bladder. Multiple sclerosis is a major cause of neurogenic detrusor overactivity, which negatively impacts quality of
Syed Imran Raza, Ashkan Heshmatzadeh Behzadi, Jon D. Blumenfeld, Sarah K. Girardi, Martin R. Prince   +4 more
doaj   +1 more source

In Patients with Neurogenic Detrusor Overactivity and Hinman’s Syndrome: Would Intravesical Botox Injections Decrease the Incidence of Symptomatic Urinary Tract Infections

Research and Reports in Urology, 2021
Mai Banakhar,1 Ahmed Yamani2 1Urology Department, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; 2Urology Department, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence: Mai BanakharUrology Department, Faculty of ...
Banakhar M, Yamani A
doaj  

Targeting neurotrophin and nitric oxide signaling to promote recovery and ameliorate neurogenic bladder dysfunction following spinal cord injury – Mechanistic concepts and clinical implications

Continence, 2023
This review summarizes the presentations made to a workshop entitled “Targeting Neurotrophin and Nitric Oxide Signaling to Promote Recovery and Ameliorate Neurogenic Bladder Dysfunction following Spinal Cord Injury – Mechanistic Concepts and Clinical ...
A.J. Kanai, K.-E. Andersson, C.H. Fry, N. Yoshimura   +3 more
doaj   +1 more source