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Neuroglia in neurodegeneration

Brain Research Reviews, 2010
Neuroglial cells are fundamental for control of brain homeostasis and they represent the intrinsic brain defence system. All forms in neuropathology therefore inevitably involve glia. The neurodegenerative diseases disrupt connectivity within brain circuits affecting neuronal-neuronal, neuronal-glial and glial-glial contacts.
Michael T. Heneka   +3 more
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Nanostructured Modulators of Neuroglia

Current Pharmaceutical Design, 2019
Biological and synthetic nanostructures can influence both glia and neurons in the central nervous system. Neurons represent only a small proportion (about 10%) of cells in the brain, whereas glial cells are the most abundant cell type. Non-targeted nanomedicines are mainly internalized by glia, in particular microglia, and to a lesser extent by ...
Dusica Maysinger, Jeff Ji
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Neuroglia: Gliosis and Focal Epilepsy [PDF]

open access: possibleScience, 1970
Normal neuroglial cells buffer the extracellular space around neurons and presynaptic terminals against increases in potassium ions. Epileptic foci resulting from brain injury are characterized by areas of intense fibrillary gliosis bordering neuronal tissue. The known pathological changes that occur in gliosis may impair glial control of extracellular
Michael C. Trachtenberg   +1 more
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Neuroglia in ageing and disease

Cell and Tissue Research, 2014
The proper operation of the mammalian brain requires dynamic interactions between neurones and glial cells. Various types of glial cells are susceptible to morpho-functional changes in a variety of brain pathological states, including toxicity, neurodevelopmental, neurodegenerative and psychiatric disorders. Morphological modifications include a change
José J. Rodríguez   +3 more
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Neuroglia in Adult Amphibians

1995
For a long time, it was unclear, how many types of glial cells occur in the nervous system of amphibians. Studies on glial cells were mainly based on metallic impregnation methods and electron microscopy, which did not always yield unequivocal results.
Gerhard Roth   +1 more
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Biology of Neuroglia

Nature, 1966
Biology of Neuroglia Edited By E. D. P. de Robertis and R. Carrea. (Progress in Brain Research, Vol. 15.) Pp. xi + 297. (Amsterdam, London and New York: Elsevier Publishing Company, 1965.) 95s.
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Ionic content of the neuroglia

Experimental Neurology, 1962
Abstract Neuronal degeneration in the lateral geniculate bodies of cats was induced by unilateral ablation of the visual cortex and bilateral enucleation. Four months later, the neurons had disappeared almost completely from the lateral geniculate ipsilateral to the cortical ablation, and there was only slight mesenchymal reaction. The water, sodium,
Bertha L. Newman   +2 more
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Morphology of Neuroglia.

Archives of Neurology, 1963
This extensively illustrated monograph contains the results of the first three years of study by a "Glia Research Group" organized in 1957 by the Japanese Ministry of Education. The eight chapters (contributed by 14 authors) include: 1) a review of neuroglial histology with numerous illustrations of metal impregnated glia in normal and pathological ...
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Neuroglia And Spinal Fluids

Journal of Experimental Biology, 1981
ABSTRACT It is quite usual to see clear fluid collecting continuously on the surface of the spinal cord of ‘functionally decapitate’ cat preparations which have no functioning choroid plexus. The activity of potassium and calcium ions in interstitial fluid of these decapitate spinal cords is equal to that in spinal cords of cats with ...
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Coupling and uncoupling of amphibian neuroglia

Neuroscience Letters, 1985
Glial cells in the optic nerve of Necturus are coupled to each other by low resistance pathways which also permit the diffusion of the fluorescent dye Lucifer Yellow CH among the cells. The spread of dye is readily observed as nuclei of cells distant from the site of intracellular injection are stained.
Paula M. Orkand   +2 more
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