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Neuroglia in ageing and disease

Cell and Tissue Research, 2014
The proper operation of the mammalian brain requires dynamic interactions between neurones and glial cells. Various types of glial cells are susceptible to morpho-functional changes in a variety of brain pathological states, including toxicity, neurodevelopmental, neurodegenerative and psychiatric disorders. Morphological modifications include a change
José J. Rodríguez   +3 more
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Neuroglia in leukodystrophies

Leukodystrophies are a heterogeneous group of rare genetic neurologic disorders characterized by white matter degeneration resulting from mutations affecting glial cells. This review focuses on the primary subtypes-astroglial, oligodendroglial, and microglial leukodystrophies-offering a detailed description of their neuropathologic features and ...
Hol, Elly M   +6 more
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Neuroglia in stroke

Stroke, ischemic or hemorrhagic, triggers a complex and coordinated glial response, which, to a large extent, defines the progression and outcome of this focal damage of the nervous tissue. Massive cell death in the infarction core results in a release of damage-associated molecular patterns, which, together with blood-borne factors entering the brain ...
Verkhratsky, Alexei   +1 more
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Neuroglia in epilepsy

Epilepsy is a group of neurologic diseases characterized by spontaneous, repetitive disruption to neuronal activity. Neurons have been at the core of epilepsy research efforts, and pharmacotherapies historically have been generated by targeting neuronal mechanisms.
Manolia R, Ghouli, Devin K, Binder
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Neuroglia in the healthy brain

The nervous tissue is composed of neurons and neuroglia, which by working in a tightly coordinated manner, define the function of the nervous system. Neuroglia, defined as homeostatic and defensive cells of the nervous system, are highly heterogeneous in form and function and are endowed with a remarkable plasticity that allows life-long adaptation to ...
Verkhratsky, A.   +4 more
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General pathophysiology of neuroglia

Neuroglia in the CNS, represented by astroglia, oligodendroglia, and microglia, are responsible for the homeostatic support and protection of the nervous tissue. Neuroglia are intimately involved in the pathogenesis of all neurologic diseases, and neuroglial changes to a large extent define the progression of these diseases and their neurologic outcome.
Verkhratsky, A.   +4 more
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Neuroglia in Adult Amphibians

1995
For a long time, it was unclear, how many types of glial cells occur in the nervous system of amphibians. Studies on glial cells were mainly based on metallic impregnation methods and electron microscopy, which did not always yield unequivocal results.
Gerhard Roth   +1 more
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Imaging neuroglia

Imaging can help us understand the role neuroglia plays in health and during the course of neurologic disorders. In vivo microscopy has had a great impact on our understanding of how neuroglia behaves during health and disease. While initially the technique was hindered by the limited penetration depth in brain tissue, recent advancements lead to ...
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Morphology of Neuroglia.

Archives of Neurology, 1963
This extensively illustrated monograph contains the results of the first three years of study by a "Glia Research Group" organized in 1957 by the Japanese Ministry of Education. The eight chapters (contributed by 14 authors) include: 1) a review of neuroglial histology with numerous illustrations of metal impregnated glia in normal and pathological ...
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Biology of Neuroglia

Nature, 1966
Biology of Neuroglia Edited By E. D. P. de Robertis and R. Carrea. (Progress in Brain Research, Vol. 15.) Pp. xi + 297. (Amsterdam, London and New York: Elsevier Publishing Company, 1965.) 95s.
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