Results 91 to 100 of about 399,982 (260)

Cerebrospinal fluid volume outperforms traditional measures for predicting treatment failure in infant hydrocephalus

Fluids and Barriers of the CNS
Background Endoscopic third ventriculostomy with choroid plexus cauterization (ETV/CPC) offers an alternative to shunt placement for infant hydrocephalus, avoiding shunt-related complications when successful. However, approximately 40% of procedures fail,
Marcia Harumy Yoshikawa, Mingzhao Yu, Julia Tatz, Hayleigh Tran, Henry A. Feldman, Ariadna S. Luviano, P. Ellen Grant, Jason Sutin, Benjamin C. Warf, Pei-Yi Lin   +9 more
doaj   +1 more source

Regenerative potential of primary adult human neural stem cells on micropatterned bio-implants boosts motor recovery

Stem Cell Research & Therapy, 2017
Background The adult brain is unable to regenerate itself sufficiently after large injuries. Therefore, hopes rely on therapies using neural stem cell or biomaterial transplantation to sustain brain reconstruction.
Carole Davoust, Benjamin Plas, Amélie Béduer, Boris Demain, Anne-Sophie Salabert, Jean Christophe Sol, Christophe Vieu, Laurence Vaysse, Isabelle Loubinoux   +8 more
doaj   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Behavioural and electrophysiological correlates of sensory attenuation in the somatosensory and auditory modality within a virtual reality setup

Scientific Reports
Sensory attenuation is the phenomenon that self-produced stimulations are suppressed compared to externally generated ones, both at the subjective and electrophysiological level.
Gianluigi Giannini, Till Nierhaus, Polina Soldatova, Felix Blankenburg   +3 more
doaj   +1 more source

Texture for neuroimaging

Texture analysis is an umbrella term for multiple image analysis techniques that quantify and characterize the distribution of the image’s gray levels.
Serranho, Pedro, Bernardes, Rui, Castelo-Branco, Miguel, Nunes, Ana   +3 more
core   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Neural processes mediating contextual influences on human choice behaviour

Nature Communications, 2016
The influence of context on value-based choice is well established but the neural correlates associated with this remain poorly understood. Here the authors perform fMRI in human subjects and find that the hippocampus and ventral tegmental area ...
Francesco Rigoli, Karl J. Friston, Raymond J. Dolan   +2 more
doaj   +1 more source

Practical neuroimaging in stroke : a case-based approach /

, 2009
Practical Neuroimaging in Stroke, by Alejandro Rabinstein, MD, and Steven J. Resnick, is a neurology reference designed for anyone involved in treating stroke patients.
Rabinstein, Alejandro A., Resnick, Steven J.   +1 more
core  

Multimodal Neuroimaging of Obesity: From Structural-Functional Mechanisms to Precision Interventions

Purpose: Obesity’s metabolic consequences are well documented; however, its neurobiological underpinnings remain elusive. This systematic review addresses a critical gap by synthesizing evidence on obesity-induced neuroplasticity across structural,
Wenhua Liu, Lang Qin, Zhiqiang Zhu, Na Li, Dongsheng Tang   +4 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source