Exploring biomarkers of neurodegeneration in epilepsy: Critical insights
Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan+7 more
wiley +1 more source
Machine learning-enhanced screening funnel for clinical trials in Alzheimer's disease. [PDF]
Gladstein S+6 more
europepmc +1 more source
Features of cognitive dysfunction in late‐onset temporal lobe epilepsy
Abstract Objective A global increase in the aging population has resulted in more patients with late‐onset epilepsy. Late‐onset temporal lobe epilepsy (LOTLE) is one of the most common types of late‐onset epilepsy and is frequently accompanied by memory impairments.
Naoya Hasegawa+2 more
wiley +1 more source
Neurological Conundrums: A Case Series on Brain Tumors Masquerading as Psychiatric Disorders. [PDF]
Srivastav A+5 more
europepmc +1 more source
Exploring cognitive and neuroimaging profiles of dementia subtypes of individuals with dementia in the Democratic Republic of Congo. [PDF]
Ikanga J+19 more
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Creativity and its link to epilepsy
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Axis I Psychiatric Disorders and Substance Abuse: A Systematic Review of Neuroimaging Findings. [PDF]
Sosa-Moscoso B+7 more
europepmc +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Imaging-validated correlates and implications of the pathophysiologic mechanisms of ageing-related cerebral large artery and small vessel diseases: a systematic review and meta-analysis. [PDF]
Ackah JA, Li X, Zeng H, Chen X.
europepmc +1 more source