Cysticerci Drive Dendritic Cells to Promote In Vitro and In Vivo Tregs Differentiation [PDF]
Clinical and Developmental Immunology, 2013 Regulatory T cells (Tregs) play a crucial role in immune homeostasis. Treg induction is a strategy that parasites have evolved to modulate the host’s inflammatory environment, facilitating their establishment and permanence.
Laura Adalid-Peralta +9 more
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Can COVID-19 pandemic worsen previous neurological/psychiatric diseases? [PDF]
Neurology Perspectives, 2022 Introduction: The SARS-CoV-2 pandemic has been affecting the world since January 2020. Although its pathogenesis is primarily directed to the respiratory tract, other organs may be affected, including the nervous system.
A. Fleury +11 more
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Increased Tc17 cell levels and imbalance of naïve/effector immune response in Parkinson’s disease patients in a two-year follow-up: a case control study [PDF]
Journal of Translational Medicine, 2021 Background Neuroinflammation has been proved to play a role in dopaminergic neuronal death in Parkinson’s disease (PD). This link highlights the relevance of the immune response in the progression of the disease. However, little is known about the impact
Diana D. Álvarez-Luquín +6 more
doaj +2 more sources
Regulatory T Cells as an Escape Mechanism to the Immune Response in Taenia crassiceps Infection [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Murine cysticercosis by Taenia crassiceps is a model for human neurocysticercosis. Genetic and/or immune differences may underlie the higher susceptibility to infection in BALB/cAnN with respect to C57BL/6 mice.
Laura Adalid-Peralta +18 more
doaj +2 more sources
Comparison of Effectiveness Between Cysticidal and Surgical Treatments in Patients with Intraventricular Neurocysticercosis: A Single-Center Experience [PDF]
PathogensNeurocysticercosis (NCC) remains a major public health problem in endemic countries. Clinical manifestations and therapeutic strategies vary depending on the location of the parasite.
Alex Aarón Agallo-Martínez +6 more
doaj +2 more sources
Immunomodulation exerted by galectins: a land of opportunity in rare cancers [PDF]
Frontiers in Immunology, 2023 Rare cancers represent only 5% of newly diagnosed malignancies. However, in some cases, they account for up to 50% of the deaths attributed to cancer in their corresponding organ.
Laura Díaz-Alvarez +4 more
doaj +2 more sources
Regulatory impairment in untreated Parkinson’s disease is not restricted to Tregs: other regulatory populations are also involved [PDF]
Journal of Neuroinflammation, 2019 Background Parkinson’s disease (PD) is the second most common neurodegenerative disease in the world. Various studies have suggested that the immune response plays a key role in this pathology.
Diana D. Álvarez-Luquín +12 more
doaj +2 more sources
Integrated Stress Response as a Therapeutic Target for CNS Injuries. [PDF]
Biomed Res Int, 2017 Central nervous system (CNS) injuries, caused by cerebrovascular pathologies or mechanical contusions (e.g., traumatic brain injury, TBI) comprise a diverse group of disorders that share the activation of the integrated stress response (ISR). This pathway is an innate protective mechanism, with encouraging potential as therapeutic target for CNS injury
Romero-Ramírez L +2 more
europepmc +2 more sources
Influencia de la infección SARS-CoV-2 sobre enfermedades neurodegenerativas y neuropsiquiátricas: ¿una pandemia demorada? [PDF]
Neurología, 2020 Resumen: Introducción: La infección por el coronavirus SARS-CoV-2 originada en diciembre de 2019 en la región china de Wuhan ha adquirido proporciones pandémicas.
P.J. Serrano-Castro +11 more
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Increased cerebrospinal fluid levels of cytokines monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-1β (MIP-1β) in patients with amyotrophic lateral sclerosis [PDF]
Neurología (English Edition), 2020 Introduction: Neuroinflammation has recently been described in amyotrophic lateral sclerosis (ALS). However, the precise role of such proinflammatory cytokines as monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-1β (MIP-1β ...
H.R. Martínez +5 more
doaj +3 more sources