Results 1 to 10 of about 52 (51)

Cysticerci Drive Dendritic Cells to Promote In Vitro and In Vivo Tregs Differentiation

Clinical and Developmental Immunology, 2013
Regulatory T cells (Tregs) play a crucial role in immune homeostasis. Treg induction is a strategy that parasites have evolved to modulate the host’s inflammatory environment, facilitating their establishment and permanence.
Laura Adalid-Peralta, Asiel Arce-Sillas, Gladis Fragoso, Graciela Cárdenas, Marcos Rosetti, Didier Casanova-Hernández, Claudia Rangel-Escareño, Laura Uribe-Figueroa, Agnes Fleury, Edda Sciutto   +9 more
doaj   +2 more sources

Regulatory T Cells as an Escape Mechanism to the Immune Response in Taenia crassiceps Infection

Frontiers in Cellular and Infection Microbiology, 2021
Murine cysticercosis by Taenia crassiceps is a model for human neurocysticercosis. Genetic and/or immune differences may underlie the higher susceptibility to infection in BALB/cAnN with respect to C57BL/6 mice.
Laura Adalid-Peralta, Laura Adalid-Peralta, Alexander Lopez-Roblero, Cynthia Camacho-Vázquez, Marisol Nájera-Ocampo, Adrián Guevara-Salinas, Nataly Ruiz-Monroy, Marlene Melo-Salas, Valeria Morales-Ruiz, Dina López-Recinos, Edgar Ortiz-Hernández, Jocelyne Demengeot, Joel A. Vazquez-Perez, Asiel Arce-Sillas, Sandra Gomez-Fuentes, Robert Michael Evans Parkhouse, Gladis Fragoso, Edda Sciutto, Edgar E. Sevilla-Reyes   +18 more
doaj   +1 more source

Fenotipos de linfocitos periféricos en las enfermedades de Alzheimer y Parkinson

Neurología, 2022
Resumen: Introducción: La neuroinflamación está involucrada en la fisiopatología de diferentes trastornos neurológicos, en particular la enfermedad de Alzheimer (EA) y la enfermedad de Parkinson (EP).
S. Garfias, B. Tamaya Domínguez, A. Toledo Rojas, M. Arroyo, U. Rodríguez, C. Boll, A.L. Sosa, E. Sciutto, L. Adalid-Peralta, Y. Martinez López, G. Fragoso, A. Fleury   +11 more
doaj   +1 more source

Increased Tc17 cell levels and imbalance of naïve/effector immune response in Parkinson’s disease patients in a two-year follow-up: a case control study

Journal of Translational Medicine, 2021
Background Neuroinflammation has been proved to play a role in dopaminergic neuronal death in Parkinson’s disease (PD). This link highlights the relevance of the immune response in the progression of the disease. However, little is known about the impact
Diana D. Álvarez-Luquín, Adrián Guevara-Salinas, Asiel Arce-Sillas, Raquel Espinosa-Cárdenas, Jaquelín Leyva-Hernández, Esteban U. Montes-Moratilla, Laura Adalid-Peralta   +6 more
doaj   +1 more source

Can COVID-19 pandemic worsen previous neurological/psychiatric diseases?

Neurology Perspectives, 2022
Introduction: The SARS-CoV-2 pandemic has been affecting the world since January 2020. Although its pathogenesis is primarily directed to the respiratory tract, other organs may be affected, including the nervous system.
A. Fleury, M.A. Del Rio Quiñones, L. Aguirre-Cruz, A. Toledo, I. Murrieta, K. Santiago, E. Uribe, L. Miranda, V. Toledo, W. Soto, D. Sánchez, L. Cruz   +11 more
doaj   +1 more source

Participación potencial del sistema inmunitario adaptativo en el desarrollo de neuropatía diabética

Revista de la Alad. Asociación Latinoamericana de Diabetes, 2021
La neuropatía diabética (ND) tiene una prevalencia alta y es una de las principales comorbilidades de la diabetes mellitus tipo 2 (DM2). La ND se asocia con una disminución de la calidad de vida y con el incremento de la tasa de mortalidad en los ...
Saul E. Cifuentes-Mendiola, Ana L. García-Hernández, Isaac O. Pérez Martínez   +2 more
doaj   +1 more source

Meta-analysis to implement alpha-synuclein in extracellular vesicles as a potential biomarker for parkinson’s disease

Revista de Investigación Clínica, 2023
Background: In Parkinson’s disease (PD), exosomes carry α-synuclein (α-syn), a fibrillar protein aggregates with potential value as a biomarker. Objective: Evidence on blood levels of exosomal α-syn in PD patients and controls was reviewed for their ...
Víctor H. Juárez-Vaquera, Marcos F. Rosetti-Sciutto, Valeria Morales-Ruiz, Laura V. Adalid-Peralta   +3 more
doaj   +1 more source

Effect of exposure to low doses of ozone on interleukin 17A expression during progressive neurodegeneration in the rat hippocampus

Neurología (English Edition), 2021
Introduction: Chronic exposure to low doses of ozone causes oxidative stress and loss of regulation of the inflammatory response, leading to progressive neurodegeneration.
H. Solleiro-Villavicencio, E. Hernández-Orozco, S. Rivas-Arancibia   +2 more
doaj   +1 more source

Regulatory impairment in untreated Parkinson’s disease is not restricted to Tregs: other regulatory populations are also involved

Journal of Neuroinflammation, 2019
Background Parkinson’s disease (PD) is the second most common neurodegenerative disease in the world. Various studies have suggested that the immune response plays a key role in this pathology.
Diana D. Álvarez-Luquín, Asiel Arce-Sillas, Jaquelín Leyva-Hernández, Edgar Sevilla-Reyes, Marie Catherine Boll, Esteban Montes-Moratilla, Viridiana Vivas-Almazán, Citzielli Pérez-Correa, Ulises Rodríguez-Ortiz, Raquel Espinoza-Cárdenas, Gladis Fragoso, Edda Sciutto, Laura Adalid-Peralta   +12 more
doaj   +1 more source

Integrated Stress Response as a Therapeutic Target for CNS Injuries

BioMed Research International, Volume 2017, Issue 1, 2017., 2017
Central nervous system (CNS) injuries, caused by cerebrovascular pathologies or mechanical contusions (e.g., traumatic brain injury, TBI) comprise a diverse group of disorders that share the activation of the integrated stress response (ISR). This pathway is an innate protective mechanism, with encouraging potential as therapeutic target for CNS injury
Lorenzo Romero-Ramírez, Manuel Nieto-Sampedro, M. Asunción Barreda-Manso, Alfredo Conti   +3 more
wiley   +1 more source