Results 141 to 150 of about 252,991 (337)

Neuroinflammation and Neurodegeneration

open access: yes, 2016
Pathophysiological processes of neurodegenerative diseases are not clearly defined. However, an important body of evidence points toward the role of various inflamma‐ tory processes. The microglial cell is the main representative of the immune system in the central nervous system (CNS).
Inelia Morales   +3 more
openaire   +3 more sources

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

open access: yesAdvanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor   +12 more
wiley   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

open access: yesAdvanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi   +4 more
wiley   +1 more source

Neuroimmune Microenvironment Reprogramming via Immuno‐piezoelectric Transducers for Synergistic Stem Cell Therapy in Traumatic Brain Injury

open access: yesAdvanced Materials, EarlyView.
A novel immuno‐piezoelectric transducer is innovatively developed. This device promotes neural stem cell (NSC) differentiation and maturation via ultrasound‐induced electrical stimulation and it amplifies the therapeutic efficacy of NSC in traumatic brain injury (TBI) by modulating the immune microenvironment. This piezoelectric transducer with “immune‐
Linlin Liang   +12 more
wiley   +1 more source

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

open access: yesAdvanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba   +20 more
wiley   +1 more source

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

open access: yesAdvanced Photonics Research, EarlyView.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka   +5 more
wiley   +1 more source

Enabling new insights from old scans by repurposing clinical MRI archives for multiple sclerosis research

open access: yesNature Communications
Magnetic resonance imaging (MRI) biomarkers are vital for multiple sclerosis (MS) clinical research and trials but quantifying them requires multi-contrast protocols and limits the use of abundant single-contrast hospital archives. We developed MindGlide,
Philipp Goebl   +23 more
doaj   +1 more source

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