Results 201 to 210 of about 135,205 (333)

Blood DDIT4 and TRIM13 Transcript Levels Mark the Early Stages of Machado–Joseph Disease

Annals of Neurology, EarlyView.
Objective An abundance of select transcripts and proteins has been found to be dysregulated in blood samples of Machado–Joseph disease (MJD) carriers. Here, we aimed to: (1) identify blood transcriptional changes as potential biomarkers of MJD; (2) correlate levels of differentially expressed blood transcripts with MJD carriers features; and (3 ...
Ana F. Ferreira, Mafalda Raposo, Emily D. Shaw, Louisa Liu, João Vasconcelos, Teresa Kay, Conceição Bettencourt, Maria Luiza Saraiva‐Pereira, Laura Bannach Jardim, Maria do Carmo Costa, Manuela Lima   +10 more
wiley   +1 more source

Neuroinflammation at the Neuroforamina and Spinal Cord in Patients with Painful Cervical Radiculopathy and Pain-Free Participants: An [¹¹C]DPA713 PET/CT Proof-of-Concept Study. [PDF]

J Clin Med
Lutke Schipholt IJ, Koop MA, Coppieters MW, van de Giessen EM, Lammerstma AA, Ter Meulen BC, Vleggeert-Lankamp C, van Berckel BNM, Bot J, van Helvoirt H, Depauw PR, Boellaard R, Yaqub M, Scholten-Peeters G.   +13 more
europepmc   +1 more source

Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs [PDF]

, 2008
Stefan Lüth, Samuel Huber, Christoph Schramm, Thorsten Buch, S Zander, Christine Stadelmann, Wolfgang Brück, David C. Wraith, Johannes Herkel, Ansgar W. Lohse   +9 more
openalex   +1 more source

AI in Neurology: Everything, Everywhere, All at Once Part 3: Surveillance, Synthesis, Simulation, and Systems

Annals of Neurology, EarlyView.
This final part 3 review builds on the practical applications discussed in part 2 and explores how artificial intelligence (AI) is transforming data management, neurological education, and neurological care across large healthcare networks and datasets. The review also highlights AI's role in real‐world and synthetic data, digital twins, and innovative
Matthew Rizzo
wiley   +1 more source

Distinct cerebral cortical perfusion patterns in idiopathic normal‐pressure hydrocephalus

Human Brain Mapping, Volume 44, Issue 1, Page 269-279, January 2023., 2023
The present study investigates cerebral blood flow (CBF) and cortical thickness using surface‐based analysis of early‐phase 18F‐florbetaben PET and MRI in patients with idiopathic normal‐pressure hydrocephalus (INPH). INPH patients had significantly increased CBF with a concomitant increase in cortical thickness in areas located in the high convexity ...
Kyunghun Kang, Shin Young Jeong, Ki‐Su Park, Myong Hun Hahm, Jaeil Kim, Ho‐Won Lee, Chi‐Hun Kim, Eunkyeong Yun, Jaehwan Han, Uicheul Yoon, Sang‐Woo Lee   +10 more
wiley   +1 more source

Senkyunolide I Improves Septicemia‐Induced Brain Dysfunction via Regulating Nrf2 and Astrocyte Activity.

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Senkyunolide I (Sen I) has a protective effect on the blood–brain barrier (BBB) in rats with sepsis‐associated encephalopathy (SAE). This study investigated whether Sen I regulates Nrf2 to ameliorate sepsis‐induced brain dysfunction (SIBD). Sixty rats were randomly assigned into Sham group, SAE group (Model group), SAE + Sen I group (72 mg/kg,
Haohao Cao, Tao Liu, Meixia Xu
wiley   +1 more source

Targeting Neuroinflammation in Preterm White Matter Injury: Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes. [PDF]

Cell Mol Neurobiol
Zhang X, Zhang Y, Peng X, Yang L, Miao J, Yue Y, Wang Y, Wang X, Zhu C, Song J.   +9 more
europepmc   +1 more source

GALECTIN-3 ROLE IN THE INTERACTION OF MICROGLIA AND AMYLOID-BETA IN VITRO

IBRO Neuroscience Reports, 2023
Lluís Camprubí-Ferrer, Emil Axell, Rosalía Fernández-Calle, Javier Frontiñan-Rubio, Tomas Deierborg   +4 more
doaj  

Neuroinflammation as a neurotoxic mechanism in alcoholism: Commentary on “Increased MCP-1 and microglia in various regions of human alcoholic brain” [PDF]

, 2008
Edith V. Sullivan, Natalie M. Zahr
openalex   +1 more source

The contribution of extracellular RNA and its derived biomaterials in disease management

BMEMat, EarlyView.
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei, Zhangyi Wang, Zixuan Qin, Qianqian Wan, Yutao Li, Franklin R. Tay, Chenyu Wang, Tong Zhang, Lina Niu   +8 more
wiley   +1 more source