Results 201 to 210 of about 308,337 (381)
NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
Advanced Science, EarlyView.NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source
Effect of Systemic Inflammation on Rat Attentional Function and Neuroinflammation: Possible Protective Role for Food Restriction [PDF]
, 2019 Brittney Yegla, Thomas C. Foster
openalex +1 more source
Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease [PDF]
, 2023 Sarah R. Ocañas +12 more
openalex +1 more source
Advanced Science, EarlyView.KYNA regulates the tumor immune microenvironment in glioblastoma. KYNA reprograms the balance between T cell exhaustion and activation to suppress glioblastoma progression through inhibiting exhaustion‐associated markers (such as PD‐1, LAG3, and TOX) and enhancing immune activation and cytotoxicity markers including granzymes GZMA and GZMB.
Di Chen +19 more
wiley +1 more source
Advanced Science, EarlyView.The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu +10 more
wiley +1 more source
Advanced Science, EarlyView.Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling +13 more
wiley +1 more source
Hyperpolarized 13C magnetic resonance spectroscopy detects toxin‐induced neuroinflammation in mice [PDF]
, 2019 Lydia M. Le Page +4 more
openalex +1 more source
N,N-Dimethylacetamide Targets Neuroinflammation in Alzheimer’s Disease in In-vitro and Ex-vivo Models [PDF]
, 2022 Zeng-Hui Wei +7 more
openalex +1 more source