Results 201 to 210 of about 240,724 (351)

Mechanism of action and therapeutic potential of S100A8/A9 in neuroinflammation and cognitive impairment: From molecular target to clinical application (Review). [PDF]

Int J Mol Med
Guan X, Zha L, Zhu X, Rao X, Huang X, Xiong Y, Guo Y, Zhang M, Zhou D, Tu Q, Wu J, Wang X, Hua F, Xu J.   +13 more
europepmc   +1 more source

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

, 2007
Liya Qin, Xuefei Wu, Michelle L. Block, Yuxin Liu, George R. Breese, Jau‐Shyong Hong, Darin J. Knapp, Fulton T. Crews   +7 more
openalex   +2 more sources

Absence of the Cellular Prion Protein Exacerbates and Prolongs Neuroinflammation in Experimental Autoimmune Encephalomyelitis [PDF]

, 2008
Shigeki Tsutsui, Jennifer Hahn, Trina Johnson, Zenobia Ali, Frank R. Jirik   +4 more
openalex   +1 more source

Nasal Delivery of Engineered Exosomes via a Thermo‐Sensitive Hydrogel Depot Reprograms Glial Cells for Spinal Cord Repair

Advanced Science, EarlyView.
Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang, Jingsong Liu, Pengfei Li, Zhibin Peng, Yubo Zhang, Yishu Liu, Mi Li, Xuqiang Gong, Daqian Liu, Enze Xu, Hongbo Yang, Yuanliang Sun, Yan Xu, Yansong Wang   +13 more
wiley   +1 more source

From nonalcoholic fatty liver disease to neuroinflammation: the role of chronic systemic inflammation. [PDF]

Metab Brain Dis
Huang X, Sang Z, Liu H, Yang J, Wang K, Qu Y, Deng H.   +6 more
europepmc   +1 more source

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source

Role of gut microbiota in neuroinflammation: a focus on perioperative neurocognitive disorders. [PDF]

Front Cell Infect Microbiol
Zhou Q, Chen T, Wang X, Xu Z, Song Y, Liu S, Ge Y, Gao J.   +7 more
europepmc   +1 more source

Neuroinflammation as a neurotoxic mechanism in alcoholism: Commentary on “Increased MCP-1 and microglia in various regions of human alcoholic brain” [PDF]

, 2008
Edith V. Sullivan, Natalie M. Zahr
openalex   +1 more source

Advancements in DNA‐Driven Precision Modulation of Cell Surface Receptor for Programmable Cellular Functions

Advanced Science, EarlyView.
DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan, Ming Cai, Yiyu Wang, Hong‐Hui Wang, Zhou Nie   +4 more
wiley   +1 more source

Chronic lipopolysaccharide exposure promotes cognitive impairments by activating TRPC6-AIM2 inflammasome signaling and the regulation of ginsenoside Rg1 in Trpc6^-/- mice. [PDF]

Behav Brain Funct
Fu Y, Zhang H, Zhu X, Liang H, Fan L, Su Y, Li W, Li W.   +7 more
europepmc   +1 more source