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Neuroinflammation and Tinnitus
2021Neuroinflammation is the central nervous system's response to: injury, infection, and abnormal neural activity. Inflammatory processes are known to mediate many diseases, and recently evidence indicates that neuroinflammation underlies hearing disorders such as presbyacusis, middle-ear disease, ototoxicity, noise-induced hearing loss, and tinnitus ...
Abraham, Shulman +5 more
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Galectins and Neuroinflammation
2014Galectins, β-galactoside-binding lectins, play multiple roles in the regulation of immune and inflammatory responses. The major galectins expressed in the CNS are galectins 1, 3, 4, 8, and 9. Under normal physiological conditions, galectins maintain CNS homeostasis by participating in neuronal myelination, neuronal stem cell proliferation, and apical ...
Hung-Lin, Chen +3 more
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Sphingolipids in Neuroinflammation
2013Sphingolipids, the main component of cellular membranes, are cellular 'jack-of-all-trades', influencing a variety of functions including signal transduction, cell activation, membrane fluidity and cell-cell interactions.In the last few years, sphingolipids have begun to be investigated in the pathophysiology of major diseases of the brain, e.g ...
Laura, Davies +2 more
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Ketogenic diet and Neuroinflammation
Epilepsy Research, 2020AbstractThe high-fat, low-carbohydrate ketogenic diet (KD) is an established and proven treatment for pharmacoresistant epilepsy. Recently, the KD has been validated as a treatment option for some inflammation-induced epileptic encephalopathies. Given the broad neuroprotective properties of the KD in various experimental models of neurologic disorders,
Sookyong Koh +2 more
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2013
It has been well established that there is bidirectional communication between the immune and central nervous systems. One context in which this interaction has been extensively studied is that of the stress response. Stress, whether physical or psychological, induces alterations in immune function.
Angela J, Grippo, Melissa-Ann L, Scotti
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It has been well established that there is bidirectional communication between the immune and central nervous systems. One context in which this interaction has been extensively studied is that of the stress response. Stress, whether physical or psychological, induces alterations in immune function.
Angela J, Grippo, Melissa-Ann L, Scotti
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Neuroinflammation in obese children
Bulletin of Experimental Biology and Medicine, 2023Obesity is associated with chronic persistent inflammation due to a pool of tissue macrophages that can penetrate the blood-brain barrier and cause neuroinflammation. The analysis of the association of CD14+CD163+ monocytes in the peripheral blood with cognitive functions in 56 obese children (mean age 11.95 (9.45; 14.45) years) was carried out.
Yu G, Samoilova +5 more
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Molecular Neurobiology
Neuroinflammation is an immune response in the central nervous system and poses a significant threat to human health. Studies have shown that the receptor serine/threonine protein kinase family (RIPK) family, a popular research target in inflammation, has been shown to play an essential role in neuroinflammation.
Yue Xu +5 more
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Neuroinflammation is an immune response in the central nervous system and poses a significant threat to human health. Studies have shown that the receptor serine/threonine protein kinase family (RIPK) family, a popular research target in inflammation, has been shown to play an essential role in neuroinflammation.
Yue Xu +5 more
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Science Signaling, 2017
The soluble form of the innate immune receptor TREM2 promotes microglial survival and inflammatory responses in the brain.
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The soluble form of the innate immune receptor TREM2 promotes microglial survival and inflammatory responses in the brain.
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Neuroinflammation and Schizophrenia
Current Psychiatry Reports, 2019There are longstanding, intriguing findings of immune dysfunction in schizophrenia. These findings span peripheral immune markers, especially cytokine abnormalities.This review describes recent genetic and immune marker studies and emergent treatment studies. Collectively, this provides a synthesis and current appraisal of the neuroimmune hypothesis of
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