Results 231 to 240 of about 252,991 (337)

Imaging Microglial Activation During Neuroinflammation and Alzheimer’s Disease

, 2008
Sriram Venneti, Clayton A. Wiley, Julia Kofler   +2 more
openalex   +2 more sources

Rev-erbs and glia—implications for neurodegenerative diseases [PDF]

, 2019
Dimitry, Julie M., Griffin, Percy, Musiek, Erik S.   +2 more
core   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source

Neuro-inflammatory response dynamics following intestinal surgery: a mini-review. [PDF]

Front Med (Lausanne)
Mu X, Sun T, Shi H.
europepmc   +1 more source

Stimulation of Toll-Like Receptor 9 by Chronic Intraventricular Unmethylated Cytosine-Guanine DNA Infusion Causes Neuroinflammation and Impaired Spatial Memory [PDF]

, 2009
Simone C. Tauber, Sandra Ebert, Jochen H. Weishaupt, Arno Reich, Roland Nau, Joachim Gerber   +5 more
openalex   +1 more source

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

Advanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie, Qiuyang Zheng, Jiaming Lv, Qian Zhang, Zhiwei Cui, Shuai Huang, Wei Yu, Binyang Chen, Wanling Que, Shanpan Fu, Yuemei Xi, Jiayu Chen, Xueling Ye, Shuyi Chen, Hairong Zhao, Tetsuya Yamamoto, Hidenori Koyama, Xin Wang, Jidong Cheng   +18 more
wiley   +1 more source

Lipid metabolic dysregulation-induced neuroinflammation in the pathophysiology of major depressive disorder. [PDF]

Front Immunol
Ge Z, Hu Y, Kan W, Li L, Xu J, Zhang Y, Zheng N, Wang G, Du J.   +8 more
europepmc   +1 more source

Ultra-Low-Dose Naloxone Restores the Antinociceptive Effect of Morphine and Suppresses Spinal Neuroinflammation in PTX-Treated Rats

, 2008
Ru‐Yin Tsai, Fong-Lin Jang, Yueh-Hua Tai, Shinn‐Long Lin, Ching‐Hui Shen, Chih‐Shung Wong   +5 more
openalex   +1 more source

T1WI‐SWI Dual Modal Magnetic Resonance Nanoprobes for Accurate Diagnosis of Early Stage Alzheimer's Disease

Advanced Science, EarlyView.
We developed a smart MRI nanoprobe targeting BACE1 and Aβ plaques. It crosses the blood‐brain barrier. Upon encountering BACE1, the probe is cleaved, enabling T1WI imaging detection. Subsequent reaction with ONOO− induces probe aggregation, enhancing magnetic susceptibility for sensitive SWI imaging of Aβ plaques.
Minghua Li, Aijun Shen, Xiaolong Gao, Chao Lin, Zongliang Huang, Qi Lv, Junjun Tang, Xiaolong Ma, Jiong Ni, Ju Tian, Jiaqi Wu, Xiaowen Xu, Wei Wang, Peijun Wang   +13 more
wiley   +1 more source

Multiparametric MRI assessment of acute neuroinflammation in a murine model of peripheral LPS stimulation. [PDF]

BMC Med Imaging
Shimshek DR, Zurbruegg S, Neuhaus A, Schubart A, Gasparini F, Beckmann N.   +5 more
europepmc   +1 more source