Results 231 to 240 of about 240,724 (351)

Neuroinflammation in Schizophrenia-Related Psychosis: A PET Study [PDF]

, 2009
Janine Doorduin, Erik F. J. de Vries, Antoon T. M. Willemsen, Jan Cees de Groot, Rudi Dierckx, Hans Klein   +5 more
openalex   +1 more source

Effects of Dictyophora polysaccharide on cerebellar Purkinje cell degeneration in a chronic alcohol mouse model

Animal Models and Experimental Medicine, EarlyView.
In an ethanol (EtOH)‐treated mouse model, increases in the NLRP3 inflammasome proteins, PC degeneration, and motor coordination disorders were observed. DIP suppressed the NLRP3‐ASC‐caspase‐1 signaling pathway, and alleviated the motor deficits and cerebellar pathological changes in chronic EtOH‐treated mice.
Jian Zhang, Zhihui Dai, Huanhuan Yu, Baofei Sun, Jiuyang Ding, Yuanhe Wang   +5 more
wiley   +1 more source

Pathological mechanisms and treatment progression of Alzheimer's disease. [PDF]

Eur J Med Res
Zhang J, Kong G, Yang J, Pang L, Li X.
europepmc   +1 more source

Establishment of a novel alloxan‐induced rabbit model exhibiting unique diabetic retinal neuropathy features assessed via ERG + VEP

Animal Models and Experimental Medicine, EarlyView.
Study workflow. Neuroretinal changes were observed in alloxan‐induced diabetic rabbits, while the retinal vasculature remained unaffected, indicating the successful establishment of a diabetic neuroretinal model. Abstract Background Diabetic retinal neuropathy (DRN) leads to significant visual impairment; however, no existing animal model fully ...
Xinlu Li, Xiaojing Dong, Defei Feng, Han Hu, Bai Li, Zhongjian Liu, Wei He, Chenchen Huang, Zhizhou Shi, Yan Mei   +9 more
wiley   +1 more source

Neuroinflammation: Advancements in Pathophysiology and Therapies. [PDF]

Int J Mol Sci
Martín-Hernández D.
europepmc   +1 more source

Toll-Like Receptor 4 Is Involved in Subacute Stress–Induced Neuroinflammation and in the Worsening of Experimental Stroke

, 2008
Javier R. Caso, Jesús M. Pradillo, Olivia Hurtado, Juan C. Leza, Marı́a A. Moro, Ignacio Lizasoaín   +5 more
openalex   +1 more source

Cistanche tubulosa improves peripheral neuropathy in MPTP‐induced PD mice based on regulation of m6A methylation

Animal Models and Experimental Medicine, EarlyView.
At steady state, DRG ensures low‐level expression of TH+ neurons under the protection of AKT. However, the DRG level of PD mouse model under MPTP toxicity increased significantly, and the expression of IL‐6 and CASP3 increased. This process was accompanied by the occurrence of m6A demethylation, with a significant increase in FTO as the main ...
Yatan Li, Wei Jia, Junhua Hu, Borui Zhang, Xinxin Qi, Jianhua Yang, Xinling Yang   +6 more
wiley   +1 more source

Zingerone as a Neuroprotective Agent Against Cognitive Disorders: A Systematic Review of Preclinical Studies. [PDF]

Int J Mol Sci
Olasehinde TA, Olaokun OO.
europepmc   +1 more source

Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: Relevance to oxidative stress and neuroinflammation in Parkinson's disease [PDF]

, 2009
Anumantha G. Kanthasamy, Huajun Jin, Suneet Mehrotra, Rajakishore Mishra, Arthi Kanthasamy, Ajay Rana   +5 more
openalex   +1 more source

Strategies for optimization of hypoglycemia rat models

Animal Models and Experimental Medicine, EarlyView.
This review focuses on rat models for studying the short‐term and long‐term effects of mild and severe hypoglycemia. We explored the physiological mechanisms to understand the consequences of hypoglycemia in rat experimental models. This study sheds light on uncovering the therapeutic potential for hypoglycemic patients and its efficacy in mitigating ...
Lee Yeong Zher, Eason Kong Qi Zheng, Rayneshia Elaura Raymond, Ye Zhen Jie, Christina Gertrude Yap   +4 more
wiley   +1 more source