Results 271 to 280 of about 212,554 (299)

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Exploring the role of apolipoprotein ε4 in progressive myoclonic epilepsy type 1

Epileptic Disorders, EarlyView.
Abstract Objective Progressive myoclonic epilepsy type 1 (EPM1) is a neurodegenerative disease caused by biallelic variants in the cystatin B (CSTB) gene. Despite a progressive course, phenotype severity varies among patients, even within families. We studied the potential role of APOE ε4 in modifying phenotypic diversity in EPM1, given its established
Janina Gunnar, Yawu Liu, Henri Eronen, Tarja Joensuu, Marja Äikiä, Jelena Hyppönen, Katri Silvennoinen, Esa Mervaala, Juhana Hakumäki, Anna‐Elina Lehesjoki, Reetta Kälviäinen   +10 more
wiley   +1 more source

The liver as a metabolic and immune hub in Alzheimer's disease: From mechanisms to therapeutic opportunities. [PDF]

J Prev Alzheimers Dis
Chen J, Wang L, Zhou Y, Zhao S, Chen Q, Zheng K.   +5 more
europepmc   +1 more source

Gut microbiota-neuroinflammation axis: A new mechanism and therapeutic target for comorbid depression in epilepsy. [PDF]

Brain Behav Immun Health
Wang X, Liu M, Cao L, Huang H, Yang J, Zhang H, Pan C, Xu Z.   +7 more
europepmc   +1 more source

Co-regulation of microglial subgroups in Alzheimer's amyloid pathology: Implications for diagnosis and drug development. [PDF]

PLoS One
Zhou Y, Huang Y, Fan Y, Xue F.
europepmc   +1 more source

Retraction: Wu ZS et al. Effect of adenovirus-mediated overexpression of PTEN on brain oxidative damage and neuroinflammation in a rat kindling model of epilepsy. Chin Med J 2019;132:2628-2635. [PDF]

Chin Med J (Engl)
europepmc   +1 more source