Results 271 to 280 of about 252,991 (337)
Advanced Science, EarlyView.Alzheimer's disease (AD) is the most common neurodegenerative disorder. This study demonstrates that microglial Rack1 deficiency decreased Aβ deposition and neuroinflammation and ameliorated cognitive impairments in AD model mice by enhancing IGF1‐mediated astrocytic phagocytosis.
Jingdan Zhang +13 more
wiley +1 more source
Exosomes in epilepsy: bridging neuroinflammation, diagnosis, and therapeutic delivery. [PDF]
Front ImmunolLi B, Zhu Y, Chen L, Cui J, Zhang Z.
europepmc +1 more source
P-Glycoprotein Acts as an Immunomodulator during Neuroinflammation
, 2009 Gijs Kooij +11 more
openalex +2 more sources
Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment
Advanced Science, EarlyView.Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr. +20 more
wiley +1 more source
Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives
Advanced Science, EarlyView.Micro/nanorobots (MNRs) offer a transformative approach for precision therapy in brain disorders. By overcoming biological barriers and enabling controlled propulsion, targeted delivery, and real‐time imaging/tracking, MNRs pave the way toward effective, minimally invasive treatments. This review outlines the interplay between brain disease challenges,
Qi Zhang, Dong Sun
wiley +1 more source
Adenosine Receptors in Neuroinflammation and Neurodegeneration. [PDF]
CellsSalmaso V +4 more
europepmc +1 more source
Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined
Aggregate, EarlyView.Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei +8 more
wiley +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino +8 more
wiley +1 more source