Results 281 to 290 of about 240,724 (351)

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Cardiac Injury Regulates Neuroinflammation Through Extracellular Vesicle-Mediated Heart-Brain Crosstalk. [PDF]

JACC Basic Transl Sci
Li Q, Hamdalla RH, Dhyani N, Sun L, Gao L, Rudebush TL, Zucker IH, Tian C.   +7 more
europepmc   +1 more source

Ketogenic diet therapy for epilepsy during pregnancy and lactation: An international survey exploring clinician perspectives

Epilepsia Open, EarlyView.
Abstract Objective Ketogenic diet therapies (KDTs) are increasingly used as a treatment for people with epilepsy of childbearing potential (PWECP) and glucose transporter type 1 deficiency syndrome (Glut1DS). The aim of this study was to collect information on clinical experience with KDT during pregnancy and lactation in these populations.
Kelly Faltersack, Tanya J. W. McDonald, Valentina De Giorgis, Bobbie Barron, Mackenzie C. Cervenka, Anita Devlin, Laura A. Healy, Magnhild Kverneland, Elles van der Louw, Mengyang Lu, Martina P. Zanaboni, Marisa Armeno, Elizabeth A. Felton   +12 more
wiley   +1 more source

Pharmacological inhibition of the cGAS-STING pathway suppresses microglia pyroptosis in sepsis-associated encephalopathy. [PDF]

J Neuroinflammation
Zeng QQ, Qi Y, Yu H, Xu Y, Chen JX, Zheng YW, Zhang GF, Zhang QL, Zheng YH, Guo J, Zhao ZH, Wang FS, Jin GL.   +12 more
europepmc   +1 more source

Associations between the gut microbiota, immune cells, and different subtypes of epilepsy: A Mendelian randomization study

Epilepsia Open, EarlyView.
Abstract Objective The gut microbiota (GM) plays a role in epilepsy development via the microbiota–gut–brain axis. However, its relationship with various epilepsy subtypes and its mediating role through immune cells remain unclear. Thus, identifying the GM linked to specific epilepsy subtypes and investigating immune mechanisms to predict epilepsy risk,
Xu Zhang, Zhenlin Yang, Jingjing Guo, Yuanxin Wei, Jinzi Li   +4 more
wiley   +1 more source

Mechanisms and interventions in aneurysmal subarachnoid hemorrhage: Unraveling the role of inflammatory responses and cell death in early brain injury (Review). [PDF]

Mol Med Rep
Lin R, Guan S, Wang J, Han M, Fan M, Wan J, Zhang X, Zhang N, Li J.   +8 more
europepmc   +1 more source

The upside of epilepsy: Theories of an evolutionary paradox

Epilepsia Open, EarlyView.
Abstract The persistence of common, heritable conditions, like epilepsy, that are associated with reduced reproductive fitness is an evolutionary paradox. Endogenous analgesic, anti‐depressant, and inflammatory mechanisms able to repair compromised functions can offer advantages in unexpected crises.
Alyssa Ailion, Christoph Helmstaedter, Annamaria Vezzani, Matthias J. Koepp   +3 more
wiley   +1 more source

Proposing Bromo-Epi-Androsterone (BEA) for Post-Traumatic Stress Disorder (PTSD). [PDF]

Cells
Dow CT, Obaid L.
europepmc   +1 more source

Altered along‐the‐perivascular space index in functional (psychogenic non‐epileptic) seizures: A diffusion tensor imaging study of glymphatic system function

Epilepsia Open, EarlyView.
Abstract Objective The glymphatic system is a critical brain waste‐clearance mechanism that facilitates the removal of metabolic byproducts and maintains neural homeostasis. Its dysfunction has been implicated in various neurological disorders; however, its role in functional (psychogenic nonepileptic) seizures (FS/PNES), a functional neurological ...
Mehrdad Roozbeh, Mehdi M. Mirbagheri, Mohammad Arbabi, Ali A. Asadi‐Pooya, Fariba Khodagholi, Saba Amiri   +5 more
wiley   +1 more source

Altered Neuroplasticity in Epilepsy is Associated with Neuroinflammation and Oxidative Stress: In vivo Evidence of Brain-Derived Extracellular Vesicles. [PDF]

Int J Nanomedicine
Wang S, Zhang H, Li R, Liu Z, Xiang D.
europepmc   +1 more source