Results 281 to 290 of about 308,337 (381)

Long‐Term Stable Subdural Recordings Enabled by Fibrosis‐Resistant Hydrogel‐Integrated µECoG Arrays

Advanced Science, EarlyView.
An adhesive hydrogel‐integrated micro‐electrocorticography (aGel‐µECoG) array is developed to ensure stable neural recordings by minimizing neuroinflammation and fibrosis during implantation. The hydrogel serves as a biological and mechanical bridge, enabling bioadhesive, reversible, anti‐fibrotic integration with brain tissue.
Lin Chen, Hao Zhong, Linghao Wang, Liju Xu, Wanying Fan, Yongpeng Zhao, Huiling Zhang, Yang Shen, Kai Wu, Xin Fu, Jingxiang Guo, Ke Li, Dong Qiu, Ting Wu   +13 more
wiley   +1 more source

5-Hydroxymethylfurfural Alleviates Lipopolysaccharide-Induced Depression-like Behaviors by Suppressing Hypothalamic Oxidative Stress and Regulating Neuroinflammation in Mice. [PDF]

Antioxidants (Basel)
Ya B, Yin H, Yuan L, Jing A, Li Y, Yan F, Zhang H, Xiong H, Zhao M.   +8 more
europepmc   +1 more source

Microglial Rack1 Deficiency Alleviates Alzheimer's Disease Pathology through Enhancing IGF1‐Mediated Astrocytic Phagocytosis

Advanced Science, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder. This study demonstrates that microglial Rack1 deficiency decreased Aβ deposition and neuroinflammation and ameliorated cognitive impairments in AD model mice by enhancing IGF1‐mediated astrocytic phagocytosis.
Jingdan Zhang, Yanling He, Pin Yang, Hengchang Zhang, Yueyang Tong, Lingling Jiang, Zehan Li, Meichen Yan, Xiaoheng Li, Qinghu Yang, Jing Yang, Zengqiang Yuan, Jiyan Zhang, Jinbo Cheng   +13 more
wiley   +1 more source

Neuroinflammation [PDF]

, 2016
openaire   +2 more sources

Amyloid beta and tau are associated with the dual effect of neuroinflammation on neurodegeneration. [PDF]

Alzheimers Dement
Povala G, Bellaver B, Bastiani MA, Ferrari-Souza JP, Aguzzoli CS, Leffa DT, Ferreira PCL, Lussier FZ, Rocha A, Zalzale H, Soares C, Bauer-Negrini G, Therriault J, Rahmouni N, Stevenson J, Servaes S, Tissot C, Zatt B, Karikari TK, Ikonomovic MD, Villemagne VL, Gauthier S, Zimmer ER, Tudorascu DL, Benedet AL, Rosa-Neto P, Pascoal TA.   +26 more
europepmc   +1 more source

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang, Chao Hou, Shuo Li, Lizhi Yang, Yiqun Lin, Sen Wang, Xiaohua Jia, Hui Hui, Wen He, Wei Zhang   +9 more
wiley   +1 more source

Neuroinflammation-informed neuroimaging-transcriptomic signatures explaining acupuncture's therapeutic effects in chronic insomnia. [PDF]

Chin Med
Lin W, Yu L, Xu H, Xiao X, Xia Z, Dou Z, Hu D, He Y, Yang L, Yang J, Zhu T, Zeng F, Yu S.   +12 more
europepmc   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Xiaoyao San against depression via glia-mediated neuroinflammation using network pharmacology and experimental validation. [PDF]

Sci Rep
Liu XY, Yan YZ, Jiang AJ, He WY, Fang YY, Li CH, Deng MF, Tan SJ, Zeng P.   +8 more
europepmc   +1 more source

Inhibition of MicroRNA-129-5p Promotes Neuroinflammation and Cognitive Impairment [PDF]

Lalit Kaurani, Jiayin Zhou, Ranjit Pradhan, Sophie Schröder, Susanne Burkhardt, Anna-Lena Schuetz, Ivana Delalle, Patrizia Rizzu, Peter Heutink, Farahnaz Sananbenesi, André Fischer   +10 more
openalex   +1 more source