Results 51 to 60 of about 2,041,651 (303)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Outcome of Neonatal Cerebral Infarction

Pediatric Neurology Briefs, 2000
The long-term neurodevelopmental outcome of CT-documented cerebral infarction was evaluated in 46 children followed for a mean of 42 months (range, 18-164 months) at the Glenrose Rehabilitation Hospital, and University of Alberta, Edmonton, Canada.
J Gordon Millichap
doaj   +1 more source

Comparison between observation of spontaneous movements and neurologic examination in preterm infants

, 1997
Objective: The Prechtl method of qualitative assessment of general movements (GMs) has been shown to be a good predictor of neurologic outcome in fetuses, preterm infants, and term infants.
Barbani MT, Einspieler C, Cioni G, Ferrari F, Prechtl HFR, FERRARI, Fabrizio, Paolicelli PB, CIONI, GIOVANNI   +7 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Es el reflejo glabelar un componente del parkinsonismo inducido por neurolépticos?

Biomédica: revista del Instituto Nacional de Salud, 2005
Introducción. La evidencia disponible sugiere que algunos signos neurológicos atribuidos al uso de neurolépticos son realmente manifestaciones secundarias de trastornos psicóticos. Objetivo.
Ricardo Sánchez, José Manuel Calvo, Luis Eduardo Jaramillo   +2 more
doaj   +1 more source

PREDICTIVE VALUE OF THE GENERAL MOVEMENTS ASSESSMENT IN PRETERM INFANTS: A META-ANALYSIS

Revista Paulista de Pediatria, 2020
Objective: To discuss the predictive value of the General Movements Assessment for the diagnosis of neurodevelopment disorders in preterm newborns. Data source: We conducted a systematic literature review using the following databases: Scientific ...
Camila da Silva Pires, Sérgio Tadeu Martins Marba, Jamil Pedro de Siqueira Caldas, Mônica de Carvalho Sanchez Stopiglia   +3 more
doaj   +2 more sources

Hypoxic-ischemic encefalopathy: Clinical course and prognosis [PDF]

Vojnosanitetski Pregled, 2003
Background. Establishing the value of neurological examination, and additional diagnostic methods (ultrasonography and magnetic resonance imaging of the brain) in the diagnosis and prognosis of hypoxic-ischemic encephalopathy and its treatment, tracking ...
Ćosić-Cerovac Nataša, Todorović Slobodanka M., Jović Nebojša J., Prostran Milica Š.   +3 more
doaj   +1 more source

The Effects of Antipsychotic Medication on Factor and Cluster Structure of Neurologic Examination Abnormalities in Schizophrenia

, 2005
This study extends a previous study of the factor structure of the neurologic examination in unmedicated schizophrenia, utilizing cluster analysis and adding a medicated condition.
Goldstein, Gerald, Forman, Steven D., Sanders, Richard D., Gurklis, John A., Van Kammen, Daniel P., Keshavan, Matcheri S., Tarpey, Thaddeus   +6 more
core   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Pyramidal and Proprioceptive Dysfunctions as the Main Neurologic Features In Symptomatic Type I Chiari Malformation Patients

Brazilian Neurosurgery, 2018
Objective Broader access to magnetic resonance imaging (MRI) has increased the diagnosis of tonsillar ectopia, with most of these patients being asymptomatic.
Bruno Corrêa de Albuquerque Leimig, Claudio Henrique Fernandes Vidal, Marcelo Moraes Valença, Joacil Carlos da Silva, Walter de Freitas Matias Filho   +4 more
doaj   +1 more source