Results 51 to 60 of about 57,981 (292)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Common Neurologic Features of Lyme Disease That May Present to a Rheumatologist

Pathogens, 2023
Lyme disease, caused by Borrelia burgdorferi (Bb) infection, has a broad spectrum of clinical manifestations and severity. Patients with possible Lyme disease may seek out or be referred to rheumatologists.
Swati Govil, Eugenio Capitle, Alexandra Lacqua, Reena Khianey, P.K. Coyle, Steven E. Schutzer   +5 more
doaj   +1 more source

Fibromuscular Dysplasia and Its Neurologic Manifestations : A Systematic Review [PDF]

, 2019
IMPORTANCE: Data on neurologic manifestations of fibromuscular dysplasia (FMD) are rare, and current knowledge remains limited. OBJECTIVES: To present a comprehensive review of the epidemiologic characteristics, management, and prognosis of the ...
Boulanger, Marion, Joux, Julien, MAJERSIK, J. J., WORRALL, B. B., Hussain, Shazam, AZIZI, M., Gornik, Heather L., Olin, Jeffrey, LABEYRIE, P. E., Southerland, Andrew,, Majersik, Jennifer, J, SOUTHERLAND, A. M., Kirton, Adam, Olin, Jeffrey W., Worrall, Bradford, PERSU, A., Olin, Jeffrey, W, GORNIK, H. L., HUSSAIN, S. M., PLOUIN, P. F., Hussain, Shazam M., Olin, Jeffrey,, Hussain, Shazam,, Gornik, Heather, Labeyrie, Paul-Emile, Gornik, Heather,, Southerland, Andrew, M, Persu, Alexandre, Sharma, Aditya, TOUZE, E., Gornik, Heather, L, BOULANGER, M., Southerland, Andrew, Majersik, Jennifer, Mocco, J., Worrall, Bradford B., Bouatia-Naji, Nabila, Worrall, Bradford, B, Majersik, Jennifer,, Le Hello, Claire, JOUX, J., Debette, Stéphanie, SHARMA, A., Worrall, Bradford,, KIRTON, A., Southerland, Andrew M., OLIN, J. W., Jeunemaitre, Xavier, Hussain, Shazam, M, Touzé, Emmanuel, JEUNEMAITRE, X., BOUATIA-NAJI, N., Azizi, Michel, Majersik, Jennifer J., Plouin, Pierre-François, LE HELLO, C.   +55 more
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Catastrophic neurologic manifestations of a common immunodeficiency syndrome

Journal of Pediatric Critical Care, 2015
A high index of suspicion is needed in pediatric patients with neurological symptoms being the sole presenting manifestation, to diagnose infection with the Human Immunodeficiency Vnus (HIV).
Nitika Agrawal, Gnanam Ram, Shiv Kumar, Bidisha Banarjee   +3 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Disturbances of sodium in critically ill adult neurologic patients: A clinical review [PDF]

, 2006
Disorders of sodium and water balance are common in critically ill adult neurologic patients. Normal aspects of sodium and water regulation are reviewed. The etiology of possible causes of sodium disturbance is discussed in both the general inpatient and
Watkiss, J, Crocker, M, Tisdall, M, Smith, M   +3 more
core  

Neurologic Complications of Common Variable Immunodeficiency [PDF]

, 2016
Common variable immunodeficiency is a rare disorder of immunity associated with a myriad of clinical manifestations including recurrent infections, autoimmunity, and malignancy.
Nguyen, Jenna Thuc-Uyen, Gundling, Katherine, Green, Ari, DeRisi, Joseph L, Wilson, Michael R   +4 more
core   +1 more source

A rare case of influenza A in a hospitalized adult presenting with encephalitis and a seizure

IDCases, 2018
Influenza A in hospitalized adults uncommonly may present with neurologic manifestations, e.g., encephalitis. Encephalitis is the most common influenza related neurologic complication in adults, However, seizures in hospitalized adults due to influenza ...
Burke A. Cunha, Gregory L. Fear, Karishma Chawla   +2 more
doaj   +1 more source