Results 131 to 140 of about 717,165 (311)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Immunotherapy for neurological diseases

, 2008
The burden of neurological diseases in western societies has accentuated the need to develop effective therapies to stop the progression of chronic neurological diseases.
Delgado, M. (Mario), Schwartz, M. (Michal), Villoslada, P. (Pablo), Moreno, B. (Beatriz), Avila, J. (Jesús), Obeso, J.A. (José A.), Pablos, J.L. (José L.), Acarin, L. (Laia), Khoury, S.J. (Samia J.), Uccelli, A. (Antonio), McGeer, P. (Patrick), Montalban, X. (Xavier), Ferrer, I. (Isidro), Martino, G. (Gianvito), Appel, S. (Stanley), Rivest, S. (Serge), Melero, I. (Ignacio)   +16 more
core  

COVID?19 Associate Neurological Complications

, 2020
2019?novel Coronavirus disease (COVID?19) is a global health problem thataffected >2.000.000 people in the world. Although the main component ofthe disease is pulmonary disturbances, recent reports suggested neurologicalmanifestations.
Baysal-Kıraç, Leyla, Uysal, Hilmi
core  

Ultrasound treatment of neurological diseases — current and emerging applications

, 2016
Like cardiovascular disease and cancer, neurological disorders present an increasing challenge for an ageing population. Whereas nonpharmacological procedures are routine for eliminating cancer tissue or opening a blocked artery, the focus in ...
Gerhard Leinenga, Gotz, Jurgen, Langton, Christian, Christian Langton, Nisbet, Rebecca, Rebecca Nisbet, Leinenga, Gerhard, Jürgen Götz   +7 more
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

LMS-based continuous reference values for the myokine musclin in serum in children and adults

Frontiers in Endocrinology
BackgroundMusclin is a myokine which is linked to muscle activity and systemic metabolic regulation. Age-specific reference values for serum musclin are lacking in both the pediatric and adult population, limiting the interpretation of circulating ...
Anne Schön, Hannah Weber, Katharina Schermuly, Anna Tschirner, Malgorzata Szaroszyk, Thomas Rebe, Jens Drube, Nele Kanzelmeyer, Ulrich Baumann, Anibh M. Das, Dieter Haffner, Maren Leifheit-Nestler   +11 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Disability at Neurological Diseases

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2014
Purpose: It is aimed to identify cases who had disability rates because of Neurological diseases and applied to Health Committee in Cukurova University Faculty of Medicine Department of Neurology.
Ahmet Evlice, Turgay Demir, Kezban Aslan, Hacer Bozdemir, Meltem Demirkiran, ilker Unal, sebnem Bicakci   +6 more
doaj  

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source