Results 11 to 20 of about 929,659 (335)

Insomnia in neurological diseases [PDF]

Neurological Research and Practice, 2021
Insomnia is defined as difficulties of initiating and maintaining sleep, early awakening and poor subjective sleep quality despite adequate opportunity and circumstances for sleep with impairment of daytime performance.
Geert Mayer, Svenja Happe, Stefan Evers, Wiebke Hermann, Sabine Jansen, Ulf Kallweit, Maria-Lucia Muntean, Dieter Pöhlau, Dieter Riemann, Michael Saletu, Melanie Schichl, Wolfgang J. Schmitt, Friederike Sixel-Döring, Peter Young   +13 more
doaj   +6 more sources

Ferroptosis in Neurological Diseases [PDF]

Frontiers in Cellular Neuroscience, 2020
Ferroptosis is mechanism for non-apoptotic, iron-dependent, oxidative cell death that is characterized by glutathione consumption and lipid peroxides accumulation.
Jia-Xin Ren, Jia-Xin Ren, Xin Sun, Xiu-Li Yan, Zhen-Ni Guo, Yi Yang   +5 more
doaj   +4 more sources

Retinal disease in neurology. [PDF]

Proceedings of the Royal Society of Medicine, 1965
R W Russell
  +8 more sources

Early activation of Toll-like receptor-3 reduces the pathological progression of Alzheimer’s disease in APP/PS1 mouse

Alzheimer’s Research & Therapy, 2023
Background Toll-like receptor 3 (TLR3) plays an important role in the immune/inflammatory response in the nervous system and is a main pathological feature of Alzheimer’s disease (AD).
Shang Wang, Taiyang Zhu, Wanyan Ni, Chao Zhou, Hui Zhou, Li Lin, Yuting Hu, Xiaoyu Sun, Jingjing Han, Yan Zhou, Guoliang Jin, Jie Zu, Hongjuan Shi, Xingxing Yang, Zuohui Zhang, Fang Hua   +15 more
doaj   +1 more source

Evaluation of Brain SPECT with 99mTc-TRODAT-1 in the Differential Diagnosis of Parkinsonism

Parkinson's Disease, 2022
Introduction. Brain SPECT with 99mTc-TRODAT-1 (SPECT-TRODAT) may be a useful tool in the differential diagnosis of Parkinsonism. Objective. To compare results of SPECT-TRODAT with clinical findings in patients with Parkinsonism. Methods. We evaluated 153
Giorgio Fabiani, Carlos Henrique Ferreira Camargo, Raul Martins Filho, Gabriel Sampaio Froehner, Hélio Afonso Ghizoni Teive   +4 more
doaj   +1 more source

Autoantibodies in neurological disease [PDF]

Nature Reviews Immunology, 2021
The realization that autoantibodies can contribute to dysfunction of the brain has brought about a paradigm shift in neurological diseases over the past decade, offering up important novel diagnostic and therapeutic opportunities. Detection of specific autoantibodies to neuronal or glial targets has resulted in a better understanding of central nervous
openaire   +3 more sources

Serum Level of Brain-Derived Neurotrophic Factor and Thrombotic Type Are Predictive of Cognitive Impairment in the Acute Period of Ischemic Strokes Patients

Neurology Research International, 2023
40–70% of patients after a stroke, including a mild one, may experience cognitive impairment. Brain-derived neurotrophic factor (BDNF) plays a significant role in the pathogenesis and rehabilitation of ischemic stroke and also affects the patients ...
Yaroslava Yu. Havlovska, Nataliya V. Lytvynenko, Anastasiia D. Shkodina   +2 more
doaj   +1 more source

Curcumin and neurological diseases [PDF]

Nutritional Neuroscience, 2020
Objectives: The beneficial effects of many substances have been discovered because of regular dietary consumption. This is also the case with curcumin, whose effects have been known for more than 4,000 years in Eastern countries such as China and India. A curcumin-rich diet has been known to counteract many human diseases, including cancer and diabetes,
Raffaella Adami, Daniele Bottai
openaire   +4 more sources

Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer’s disease

Alzheimer’s Research & Therapy, 2022
Background Gangliosides are highly enriched in the brain and are critical for its normal development and function. However, in some rare neurometabolic diseases, a deficiency in lysosomal ganglioside hydrolysis is pathogenic and leads to early-onset ...
James C. Dodge, Thomas J. Tamsett, Christopher M. Treleaven, Tatyana V. Taksir, Peter Piepenhagen, S. Pablo Sardi, Seng H. Cheng, Lamya S. Shihabuddin   +7 more
doaj   +1 more source

The neurological disease ontology [PDF]

Journal of Biomedical Semantics, 2013
Abstract Background We are developing the Neurological Disease Ontology (ND) to provide a framework to enable representation of aspects of neurological diseases that are relevant to their treatment and study. ND is a representational tool that addresses the need for unambiguous annotation, storage, and retrieval of ...
Kinga Szigeti, Patrick Ray, Alexander D. Diehl, Bianca Weinstock-Guttman, Naveed Chaudhry, Mark Jensen, Marcus Ng, Barry Smith, Alexander P. Cox, William D. Duncan, Donat Sule, Alan Ruttenberg   +11 more
openaire   +2 more sources