Results 11 to 20 of about 1,009,699 (333)

Astroglia In Neurological Diseases [PDF]

Future Neurology, 2013
Astroglia encompass a subset of versatile glial cells that fulfill a major homeostatic role in the mammalian brain. Since any brain disease results from failure in brain homeostasis, astroglial cells are involved in many, if not all, aspects of neurological and/or psychiatric disorders.
Vladimir Parpura, Alexei Verkhratsky, José J. Rodríguez, José J. Rodríguez   +3 more
openaire   +3 more sources

Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2 [PDF]

, 2020
Background and purpose Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported.
Boon, Paul, De Herdt, Veerle, Garrez, Ieme, Hemelsoet, Dimitri, Laureys, Guy, Raedt, Robrecht, Vonck, Kristl   +6 more
core   +2 more sources

Pseudo Chiari with holocord syringomyelia secondary to cerebrospinal fluid hypotension. Case report

Interdisciplinary Neurosurgery, 2022
Introduction: Pseudo-Chiari malformation results from caudal displacement of brain structures secondary to cerebrospinal fluid (CSF) hypotension. Some case reports in the syringomyelia literature are associated with a pseudo-Chiari malformation.
Emiliano Lorefice, Sebastián J.M Giovannini, Andrés Cervio, Santiago Condomí Alcorta, Rubén Mormandi   +4 more
doaj   +1 more source

Sterol auto-oxidation adversely affects human motor neuron viability and is a neuropathological feature of amyotrophic lateral sclerosis

Scientific Reports, 2021
Aberrant cholesterol homeostasis is implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disease that is due to motor neuron (MN) death. Cellular toxicity from excess cholesterol is averted when it is enzymatically
James C. Dodge, Jinlong Yu, S. Pablo Sardi, Lamya S. Shihabuddin   +3 more
doaj   +1 more source

Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017. [PDF]

, 2017
This is a report on the CNS barrier congress held in London, UK, March 22-23rd 2017 and sponsored by Kisaco Research Ltd. The two 1-day sessions were chaired by John Greenwood and Margareta Hammarlund-Udenaes, respectively, and each session ended with a ...
A Brenn, A Reijerkerk, B Zhang, C Cerutti, DA Ridder, EJ Duh, ES Lippmann, GK Dogbevia, HC Helms, HC Helms, I Loryan, I Loryan, J Greenwood, J Keaney, J Korbelin, JA Ford, M Brkic, M Campbell, M Campbell, MA Lopez-Ramirez, O Huber, P Canning, R Martinelli, RE Vandenbroucke, S Balusu, S Dragoni, Y Hu, Y Molino, YH Chen   +28 more
core   +7 more sources

Immunotherapy for neurological diseases

Clinical Immunology, 2008
The burden of neurological diseases in western societies has accentuated the need to develop effective therapies to stop the progression of chronic neurological diseases. Recent discoveries regarding the role of the immune system in brain damage coupled with the development of new technologies to manipulate the immune response make immunotherapies an ...
P. Villoslada, B. Moreno, I. Melero, J. L. Pablos, G. Martino, UCCELLI, ANTONIO, X. Montalban, J. Avila, S. Rivest, L. Acarin, S. Appel, S. J. Khoury, P. McGeer, I. Ferrer, M. Delgado, J. Obeso, M. Schwartz   +16 more
openaire   +7 more sources

Functional connectivity of the language area in migraine: a preliminary classification model

BMC Neurology, 2023
Background Migraine is a complex disorder characterized by debilitating headaches. Despite its prevalence, its pathophysiology remains unknown, with subsequent gaps in diagnosis and treatment.
Chen Gou, Shuangfeng Yang, Qianmei Hou, Peter Rudder, Onur Tanglay, Isabella Young, Tingting Peng, Weiwei He, Liuyi Yang, Karol Osipowicz, Stephane Doyen, Negar Mansouri, Michael E. Sughrue, Xiaoming Wang   +13 more
doaj   +1 more source

Epigenetics and triplet-repeat neurological diseases [PDF]

, 2015
The term ‘junk DNA’ has been reconsidered following the delineation of the functional significance of repetitive DNA regions. Typically associated with centromeres and telomeres, DNA repeats are found in nearly all organisms throughout their genomes ...
Festenstein, RJ, Nageshwaran, S
core   +2 more sources

Biomarker and genomic analyses reveal molecular signatures of non-cardioembolic ischemic stroke

Signal Transduction and Targeted Therapy, 2023
Acute ischemic stroke (AIS) is a major cause of disability and mortality worldwide. Non-cardioembolic ischemic stroke (NCIS), which constitutes the majority of AIS cases, is highly heterogeneous, thus requiring precision medicine treatments.
Lingling Ding, Yu Liu, Xia Meng, Yong Jiang, Jinxi Lin, Si Cheng, Zhe Xu, Xingquan Zhao, Hao Li, Yongjun Wang, Zixiao Li   +10 more
doaj   +1 more source

A Prospective Study Comparing Subperiosteal Versus Subdural Drain After Burr-hole Drainage of Chronic Subdural Hematoma

National Board of Examinations Journal of Medical Sciences, 2023
Aims: The aim of our study was to perform a comparison between the efficacy of subperiosteal drain and subdural drain, and to evaluate any differences in terms of functional outcome in the treatment of symptomatic CSDH.
Mohammad Sarwar, Laxminarayan Tripathy, Harsh Jain, Sunandan Basu   +3 more
doaj   +1 more source