Results 221 to 230 of about 3,232,639 (308)

Diagnostic and Prognostic Value of Epigenetic Markers in Neurological Diseases. A Narrative Review. [PDF]

Cell Mol Neurobiol
Grodzka O, Wołos J, Kupc M, Ahmadova S, Eyileten C, Domitrz I.   +5 more
europepmc   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Consensus recommendations for next-generation sequencing-based genetic testing in Rare Neurological diseases. [PDF]

Eur J Hum Genet
Maver A, Lohmann K, Urbanczyk LM, Arnesen A, Barić I, Bauer P, Bhatia KP, Boesch S, Borovečki F, Brüggemann N, Fang ZH, Gabriel H, Haack TB, Houlden H, Janković M, Kamsteeg EJ, Mancuso M, Mascalzoni D, Molnar MJ, Münchau A, Neveling K, Novaković I, Peterlin B, Schols L, Schuermans N, Shiels K, Sturm M, Taylor R, Tijssen MAJ, Vissers LELM, Williams V, Graessner H, European Reference Network for Rare Neurological Disorders (ERN-RND).   +32 more
europepmc   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

When R-Loops Go Awry: Genome Instability and Neurological Diseases. [PDF]

Eur J Neurosci
Rasli NR, Katsuyama Y.
europepmc   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Extracellular vesicles as minimally invasive biomarkers and therapeutic platforms in rare neurological diseases. [PDF]

Front Aging
Phan ND, Sharma RR, Subramanian S, Kartha RV.   +3 more
europepmc   +1 more source

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton, Carol Hermon, Sarah Floud, Gillian Reeves, Isobel Barnes   +4 more
wiley   +1 more source