Results 241 to 250 of about 10,652,159 (339)

5. Neurological Involvement in Connective Tissue Diseases

, 2013
Shunsei Hirohata
openalex   +2 more sources

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich, Tilman Schneider‐Hohendorf, Eric Baetscher, Evan L. Riddle, Marie Deffner, Emily Katsnelson, Janine Ferrant‐Orgettas, Julie Czerkowicz, John Anderson, Susan E. Goelz, Nicholas Schwab   +10 more
wiley   +1 more source

Editorial: Neuronal guidance signaling in health and neurological diseases. [PDF]

Front Cell Dev Biol
Yamagishi S, Hiramoto M, Yuasa-Kawada J.
europepmc   +1 more source

The effect of changes in society, economy and public health on the disease burden of neurological, mental and substance use disorders: a global longitudinal study [PDF]

, 2019
Yankun Sun, Yao Yao, Yanping Bao, Yan Sun, Le Shi, Jie Shi, Lin Lü   +6 more
openalex   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

Neuroglobin: A promising candidate to treat neurological diseases. [PDF]

Neural Regen Res
Yañez IM, Torres-Cuevas I, Corral-Debrinski M.   +2 more
europepmc   +1 more source

Progress and Application of Ferroptosis Mechanisms in Neurological Diseases [PDF]

openalex   +1 more source

SARS-CoV-2 infection of the nervous system: A review of the literature on neurological involvement in novel coronavirus disease-(COVID-19)

, 2020
Alvin Oliver Payus, Constance Liew Sat Lin, Malehah Mohd Noh, Mohammad Saffree Jeffree, Azman Ali Raymond   +4 more
openalex   +2 more sources

Functional brain alterations in auditory hallucination subtypes in individuals with auditory hallucinations without the diagnosis of specific neurological diseases and mental disorders at the current stage [PDF]

, 2019
Xiaodong Lin, Chuanjun Zhuo, Gongying Li, Jie Li, Xiangyang Gao, Ce Chen, Deguo Jiang   +6 more
openalex   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source