Results 231 to 240 of about 1,882,529 (345)

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

Neurological Manifestations of Snakebite Envenoming

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Jamir P. Rissardo, Ana L. F. Caprara
doaj   +1 more source

Phenotype Correlations of Neurological Manifestations in Wolfram Syndrome: Predictive Modeling in a Spanish Cohort. [PDF]

Diagnostics (Basel)
Esteban-Bueno G, Botella LM, Fernández-Martínez JL.   +2 more
europepmc   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Neurological manifestations of chronic graft versus host disease. [PDF]

Intern Med J
Koren T, Kwok A, Stevenson W, Ahmad K, Nogajski J, Parratt J, Kerridge I, Ng K.   +7 more
europepmc   +1 more source

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

Advanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan, Peng Li, Yue Wang, Xin Qi, Wanyu Wang, Yongzhong Cheng, Huabin Zhang, Xin Hu, Xiang Gao   +8 more
wiley   +1 more source

Neurological Manifestations in Adult Survivors of Ebola Virus Disease.

JAMA Neurol
Billioux BJ, Reilly C, van Ryn C, Smith B, Tarfeh-Burnette H, Dorbor J, Bonarwolo K, Taryor V, Schindler MK, Reoma LB, Azodi S, Ohayon J, Enose-Akahata Y, Bishop R, Higgs E, Lane HC, Johnson K, Sneller MC, Fallah M, Nath A.   +19 more
europepmc   +1 more source

Neurological manifestations of Sjogren syndrome: A case series. [PDF]

J Family Med Prim Care
Gupta K, Mahto SK, Sheoran A, Singh A, Pasricha N, Agarwal N.   +5 more
europepmc   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Neurological Manifestations of Aluminum Phosphide (Wheat-Pill/Rice-Pill) Poisoning: A Narrative Review. [PDF]

Cureus
Rasheed A, Hassan SH, Mehmood Qadri H, Ahmed AB, Ahmed M, Khan H, Fatima N, Azam A, Dar SA, Khawaja AA.   +9 more
europepmc   +1 more source