Results 161 to 170 of about 1,839,175 (269)

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Breathe, Eat, Talk: Three Essential Ingredients to Quality‐of‐Life Outcomes in Movement Disorders

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Breathing, eating, and talking (BET) impairments are common yet frequently underrecognized features of movement disorders. Deficits in respiration, swallowing, voice, and speech may emerge early in the course of a disease, adversely affecting safety, participation, and quality of life.
John Dean   +16 more
wiley   +1 more source

Defining the Clinical Phenotypic Ground Truth: Expert Interrater Agreement in Hyperkinetic Movement Disorders

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Reliable clinical phenotyping is crucial for diagnosis, treatment, and research in hyperkinetic movement disorders, yet its interrater reliability remains uncertain. Objectives To quantify interrater agreement in clinical phenotyping of hyperkinetic movement disorders among experts in a large, phenotypically diverse cohort.
Madelein van der Stouwe   +43 more
wiley   +1 more source

Lewy Body Disease Across Aging: Clinical and Neuropathological Correlates in a Population Brain Bank

open access: yesMovement Disorders, EarlyView.
Abstract Background Lewy body disease (LBD) is defined by neuronal α‐synuclein pathology, but how Braak‐staged LBD relates to mixed neuropathology and clinical manifestations within a single population‐based cohort remains incompletely characterized. This is especially relevant in cohorts enriched for younger individuals, which may better inform real ...
Vitor Ribeiro Paes   +13 more
wiley   +1 more source

Neurological Soft Signs and Brain Abnormalities in Schizophrenia: A Literature Review. [PDF]

open access: yesCureus, 2020
Rathod B   +8 more
europepmc   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti   +6 more
wiley   +1 more source

Investigating the Prevalence of Neurological Soft Signs in Children with Autism Spectrum Disorder and their Siblings: A Cross-Sectional Study. [PDF]

open access: yesIran J Child Neurol
Razjouyan K   +7 more
europepmc   +1 more source

Toward Brain Biosignature at 7 T—Repeatability of a Multiparametric CEST, QSM, QTI, and Sodium Imaging Protocol

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To evaluate the repeatability of an extended multiparametric 7 T MRI protocol for voxel‐wise tissue characterization combining morphological, CEST, QSM, QTI, and Sodium contrasts. Methods A repeatability study was performed in 12 volunteers without diagnosed neurological disease on a 7 T MRI system, using a comprehensive acquisition ...
Annika Hofmann   +30 more
wiley   +1 more source

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