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Neurological “soft signs” in children and adolescents
Journal of Pediatric Neurology, 2015Neurological “soft signs” (NSS) are defined as minor abnormalities in the neurological examination in subjects with no other features of fixed or transient neurologic disorders [1]. These clinical disabilities are often associated with behavior, coordination and learning difficulties.
PAOLA IANNETTI +2 more
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Soft Neurological Signs and Impulsivity in Children
Journal of Developmental & Behavioral Pediatrics, 1990To evaluate the relationship between soft neurological signs and various proposed dimensions of impulsivity (behavioral and cognitive), 31 boys (6-13 years, mean +/- SD 10.1 +/- 1.8) with disruptive behavior disorders, and 45 age-matched boys without DSM-III-R pathology, were independently assessed on clinical ratings of impulsivity, a battery of ...
B, Vitiello +3 more
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Neurologic Soft Signs in Borderline Personality Disorder
The Journal of Clinical Psychiatry, 2006Borderline personality disorder is a disabling and dramatic psychiatric condition. To date, its pathophysiology remains unclear. Scientific evidence seems to have found underlying, nonfocal, central nervous system dysfunction in borderline personality disorder.
De la Fuente, José Manuel +5 more
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Neurological soft signs predict outcomes in schizophrenia
Nature Reviews Neurology, 2020Neurological soft signs (NSS) are minor motor and sensory changes that accompany the typical psychopathological symptoms and neuropsychological deficits that manifest in the early stages of schizophrenia. A new study provides evidence that NSS in early schizophrenia predict the long-term clinical outcomes of this condition.
Johannes, Schröder, Pablo, Toro
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Correlates of neurological soft signs in bipolar disorder
European Archives of Psychiatry and Clinical Neuroscience, 2023Recent research has focused on neurological soft signs (NSS) in bipolar disorder (BD), but there is still scarce evidence on their correlates with other relevant variables. The aim of this study was to explore the association between NSS and clinical demographic, neurocognitive, and functional variables.
Marina P. Valerio +3 more
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Archives of General Psychiatry, 1985
Sixty-three male and 27 female adolescents known to have had neurological soft signs at the age of 7 years were compared with controls with no soft signs at age 7. Adolescents with early soft signs had significantly lower IQs and were more likely to have a psychiatric disorder characterized by anxiety, withdrawal, and depression. All the girls and 80% (
D, Shaffer +6 more
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Sixty-three male and 27 female adolescents known to have had neurological soft signs at the age of 7 years were compared with controls with no soft signs at age 7. Adolescents with early soft signs had significantly lower IQs and were more likely to have a psychiatric disorder characterized by anxiety, withdrawal, and depression. All the girls and 80% (
D, Shaffer +6 more
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Soft Neurological Signs and Their Significance
1995Abstract Neurological soft signs are minimal and difficult-to-assess impairments of neurological functions. Historically, they have been described as indicators of mini mal brain damage (MBD) in children with a variety of different problems of behavior, emotion, and learning.
Otfried Spreen +2 more
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Reliability of Subtle (Soft) Neurological Signs in Children
Journal of the American Academy of Child & Adolescent Psychiatry, 1989Reliability and stability of neurological "subtle" ("soft") signs were assessed in 54 psychiatric patients and 25 normal children, aged 5-17 years, using the revised Neurological Examination for Subtle Signs (NESS). Acceptable interrater reliability (kappa greater than or equal to 0.50, or intraclass correlation coefficient greater than or equal to 0 ...
VITIELLO, BENEDETTO +4 more
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Neurological soft signs in primary headache patients
Neuroscience Letters, 2015Neurological soft signs (NSS) are semeiotic anomalies not assessed by the standard neurological examination, primarily developed in psychiatric settings and recently proposed as potential markers of minor brain circuit alterations, especially the cerebellar-thalamic-prefrontal network.
TREMOLIZZO, LUCIO +5 more
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Neurological soft signs in Fibromyalgia.
2023Objective—To assess neurological soft signs (NSS) in individuals with fibromyalgiasyndrome (FMS) and to evaluate its relationship with disease severity.Methods—Patients with FMS (n=30) and healthy controls (n=30) underwent systematicneurological examination and assessment of NSS with Neurological Evaluation Scale (NES)by a neurologist blinded to ...
Boran, Hürrem Evren +3 more
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