Results 131 to 140 of about 50,292 (309)
Abstract Objective This study was undertaken to provide an overview of the research landscape and evaluate the impact of lifestyle modifications on seizure reduction and quality of life in people with epilepsy receiving standard medical treatment. Methods Following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) guidelines ...
Elizabeth Spurgeon +9 more
wiley +1 more source
Abstract Objective This study was undertaken to evaluate the safety and effectiveness of responsive thalamic stimulation as adjunctive therapy for drug‐resistant idiopathic generalized epilepsy (IGE) with generalized tonic–clonic seizures (GTCSs). Methods NAUTILUS is a prospective, multicenter, single‐blind, randomized sham‐controlled pivotal trial ...
Utku Uysal +47 more
wiley +1 more source
Individual‐specific resting‐state networks predict language dominance in drug‐resistant epilepsy
Abstract Objective This study was undertaken to reliably estimate individual‐specific resting‐state cortical networks and determine whether language network topography can predict task‐based language dominance in drug‐resistant epilepsy. Methods We utilized a multisession hierarchical Bayesian model (MS‐HBM) trained on drug‐resistant epilepsy patients ...
Mervyn Jun Rui Lim +7 more
wiley +1 more source
Pediatric epilepsy surgery: Global survey of invasive explorations
Abstract Objective Invasive presurgical evaluation plays a key role in pediatric epilepsy surgery, particularly in magnetic resonance imaging (MRI)‐negative cases, by guiding resective, disconnective, or ablative procedures. This International League Against Epilepsy (ILAE) Pediatric Epilepsy Surgery Taskforce study provides an updated global overview ...
Georgia Ramantani +96 more
wiley +1 more source
Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy
Abstract Objective In patients with drug‐resistant epilepsy who undergo anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS), efficacy is assessed months after therapy initiation and clinicians have no guidance when choosing stimulation parameters due to the lack of real‐time biomarkers.
Zachary T. Sanger +10 more
wiley +1 more source
Anterior cingulate cortex neuron subtypes differentially regulate seizures
Abstract Objective This study aimed to investigate the regulatory roles of distinct neuronal subtypes within the anterior cingulate cortex (ACC) in acute seizures and to identify cell type‐specific mechanisms underlying seizure modulation in this region. Methods Acute seizure models were established in mice via pentylenetetrazol injection.
Ziqian Yan +12 more
wiley +1 more source
Novel planning pipeline utilizing the Surgical Theater system for pediatric epilepsy surgery
Abstract Objective Advances in the analysis and collation of radiographic datasets have enhanced presurgical planning for various neurosurgical procedures, including clipping of cerebral aneurysms, surgical resection of tumors, and arteriovenous malformation management.
Lisa B. E. Shields +4 more
wiley +1 more source

