Results 121 to 130 of about 7,807 (215)
Epilepsia, EarlyView.Abstract The implantation effect refers to a transient reduction in seizure frequency following intracranial electrode insertion in patients with epilepsy, independent of therapeutic intervention. This retrospective study examined potential clinical and demographic predictors of the implantation effect in 51 patients who underwent ...
Shreyashish Roy‐Chowdhury +8 more
wiley +1 more source
Seizure forecasting: The long and winding road to clinical translation
Epilepsia, EarlyView.Abstract Seizure forecasting has progressed from theoretical aspiration to a rapidly advancing research domain, yet clinical translation remains limited. Over the past decades, advances in algorithm development, chronic electroencephalography (EEG), wearable sensors, and the characterization of seizure cycles have demonstrated that seizure risk is not ...
Philippa J. Karoly +7 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Use of neuromodulation strategies targeting thalamic nuclei, including deep brain stimulation (DBS) and responsive neurostimulation (RNS), for treatment of pediatric drug‐resistant epilepsy (DRE) is increasing, despite limited evidence for efficacy and safety. We present the initial results from the Comparative Multicenter Evaluation
Samuel A. Tenhoeve +28 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective This study was undertaken to evaluate the safety, feasibility, and efficacy of low‐intensity focused ultrasound (LIFU) as a noninvasive neuromodulation technique in patients with drug‐resistant epilepsy (DRE). Methods In this pilot, single‐blind, randomized sham‐controlled crossover trial, 12 patients with DRE underwent both LIFU and
Chien‐Chen Chou +8 more
wiley +1 more source
Electroclinical features and dynamic network connectivity of orbitofrontal epilepsy
Epilepsia, EarlyView.Abstract Objective Orbitofrontal epilepsy (OFE) is rare and underrecognized. This study aims to characterize electroclinical features and dynamic network connectivity of OFE and subtypes. Methods We retrospectively analyzed 17 patients with OFE who underwent stereoelectroencephalographic (SEEG) electrode implantation and epilepsy surgery at our center.
Meixuan Ren +13 more
wiley +1 more source
Perils and progress in epilepsy surgery utilization: Twenty‐five years later
Epilepsia, EarlyView.Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley +1 more source
Monthly or menstrual? A scoping review of catamenial epilepsy and non‐menstrual seizure rhythms
Epilepsia, EarlyView.Abstract Objective Despite the reported high prevalence of catamenial epilepsy (CE), the condition remains poorly defined, with lack of consensus on what entails a menstrual‐related seizure exacerbation. Emerging evidence of multiday cycles of seizure activity, including about‐monthly cycles, present in both men and women, further confound the ...
Victoria Wong +4 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Interictal epileptiform spikes (IESs) are widely used biomarkers of epileptogenic tissue in presurgical epilepsy evaluation. However, their reliability for seizure onset zone (SOZ) localization in high‐density intracranial electroencephalography (iEEG) remains inconsistent.
Amir Hossein Ayyoubi +16 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Resective surgery achieves seizure freedom in approximately 60%–80% of patients with drug‐resistant temporal lobe epilepsy (TLE), yet the extent to which seizure cessation permits recovery of disrupted functional brain networks remains unclear.
Addison C. Cavender +15 more
wiley +1 more source
Novel planning pipeline utilizing the Surgical Theater system for pediatric epilepsy surgery
Epilepsia Open, EarlyView.Abstract Objective Advances in the analysis and collation of radiographic datasets have enhanced presurgical planning for various neurosurgical procedures, including clipping of cerebral aneurysms, surgical resection of tumors, and arteriovenous malformation management.
Lisa B. E. Shields +4 more
wiley +1 more source