Results 101 to 110 of about 91,701 (298)

Clinical recommendations for non-invasive ultrasound neuromodulation

Brain Stimulation
Non-invasive ultrasound neuromodulation has experienced exponential growth in the neuroscientific literature, recently also including clinical studies and applications.
Roland Beisteiner, Andres Lozano, Vincenzo Di Lazzaro, Mark S. George, Mark Hallett   +4 more
doaj   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

Neuromodulation for Epilepsy

Neurologia medico-chirurgica
In patients with an unresectable epileptic focus, such as an undefined focus or epileptic focus within functional areas, various neuromodulation therapies, including vagus nerve stimulation, deep brain stimulation, and responsive neurostimulation, have been adopted as alternative treatment modalities.
ENATSU, Rei, KANNO, Aya, MIKUNI, Nobuhiro   +2 more
openaire   +4 more sources

Microfabrication Technologies for Nanoinvasive and High‐Resolution Magnetic Neuromodulation

Advanced Science
The increasing demand for precise neuromodulation necessitates advancements in techniques to achieve higher spatial resolution. Magnetic stimulation, offering low signal attenuation and minimal tissue damage, plays a significant role in neuromodulation ...
Changhao Ge, Tahereh Masalehdan, Mahdieh Shojaei Baghini, Vicente Duran Toro, Lorenzo Signorelli, Hannah Thomson, Danijela Gregurec, Hadi Heidari   +7 more
doaj   +1 more source

Electrophysiological Guidance of Epidural Electrode Array Implantation over the Human Lumbosacral Spinal Cord to Enable Motor Function after Chronic Paralysis. [PDF]

, 2019
Epidural electrical stimulation (EES) of the spinal cord has been shown to restore function after spinal cord injury (SCI). Characterization of EES-evoked motor responses has provided a basic understanding of spinal sensorimotor network activity related ...
Beck, Lisa A, Brown, Desmond A, Calvert, Jonathan S, Edgerton, V Reggie, Gerasimenko, Yury P, Gill, Megan L, Grahn, Peter J, Lavrov, Igor A, Lee, Kendall H, Linde, Margaux B, Lopez, Cesar, Sayenko, Dimitry G, Strommen, Jeffrey A, Van Straaten, Meegan G, Veith, Daniel D, Zhao, Kristin D   +15 more
core  

Wireless, Adaptable and Fully Implantable Battery‐powered Devices for Optical Stimulation of the Spinal Cord in Small Rodents

Advanced Science, EarlyView.
Current technologies for spinal cord optogenetic stimulation rely on external power sources and face reliability constraints in freely behaving animals. Here, a fully implantable, battery‐powered optoelectronic device is introduced, enabling operation in any selected environment with wireless recharging for months‐long stimulation.
Shahriar Shalileh, Adan Moallemi, Elham Mohseni Vadeghani, Samuel Tretjakov, Brianna Tsuyuki, Alexander Golab, Benjamin Rever, Wolfram Tetzlaff, Dena Shahriari   +8 more
wiley   +1 more source

Biphasic Electrostimulation Artifact Model for ECAP Extraction in Spinal Cord Stimulation

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Evoked compound action potential (ECAP) is extensively used as biomarker for neural activity in closed-loop spinal cord stimulation (SCS). However, accurate monitoring of neural activity is challenged by the low signal-to-noise ratio of ECAP recording ...
Haochen Zhang, Xuesong Luo, Bozhi Ma, Luming Li, Xulan Yin, Zhongwei Luo, Boyang Zhang, Xi Zhang, Hongda Li, Qingyu Yao, Junhong Lim   +10 more
doaj   +1 more source

Neuroprosthetic-enabled control of graded arm muscle contraction in a paralyzed human

Scientific Reports, 2017
Neuroprosthetics that combine a brain computer interface (BCI) with functional electrical stimulation (FES) can restore voluntary control of a patients’ own paralyzed limbs.
David A. Friedenberg, Michael A. Schwemmer, Andrew J. Landgraf, Nicholas V. Annetta, Marcia A. Bockbrader, Chad E. Bouton, Mingming Zhang, Ali R. Rezai, W. Jerry Mysiw, Herbert S. Bresler, Gaurav Sharma   +10 more
doaj   +1 more source

Giant Conductivity Modulation and Chemical Neuromodulation via Proton‐Electron Coupling in a Hydrogen‐Bonded Coordination Polymer

Advanced Science, EarlyView.
A “de‐doping” strategy positions mixed protonic–electronic conductors (MPECs) as adaptive neuromorphic platforms with dynamically tunable transport. Co‐BAND achieves giant conductivity modulation (>106) and chemically tunable synaptic plasticity. Analogous to biological neuromodulation, solvent vapors dynamically reprogram the device's learning rules ...
Kwangmin Park, Jumin Park, Huiyeong Ju, Nasim Arafat, Byoung Gwan Lee, Joohee Oh, Eejin Jang, Hyunseob Lim, Seok Min Yoon, Dae‐Woon Lim, Intek Song   +10 more
wiley   +1 more source