Results 81 to 90 of about 91,701 (298)

Robot Dream

, 2016
In this position paper we present a novel approach to neurobiologically plausible implementation of emotional reactions and behaviors for real-time autonomous robotic systems. The working metaphor we use is the "day" and "night" phases of mammalian life.
Mazzara, Manuel, Safina, Larisa, Talanov, Max, Tchitchigin, Alexander   +3 more
core   +1 more source

Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor

Advanced Science, EarlyView.
Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang, Yixiang Deng, Nan Xia, Shuzo Sugita, Shangbang Gao   +4 more
wiley   +1 more source

Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output

Advanced Science, EarlyView.
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin, Shulan Xiao, Krishna Jayant   +2 more
wiley   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, EarlyView.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Miniaturized Bidirectional Thermal Stimulation System Integrated With an Electrode Array for Recording Neural Activities

Advanced Science, EarlyView.
This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina, Kanghwan Kim, Wesley Charles Smith, Keuntae Kim, Shinwoo Lee, Jiwan Woo, Il‐Joo Cho   +6 more
wiley   +1 more source

Feasibility study of transcranial direct current stimulation (tDCS) efficacy in patients with neurogenic dysphagia: Study Protocol

MethodsX
Non-invasive brain stimulation (NIBS) techniques have shown increasing scientific relevance due to their potential positive effects across several health domains, including rehabilitation and clinical treatment.
Carolina Fiorin Anhoque, Bárbara Aguiar do Sacramento da Silva, Luana Ximenes Comarela, Amanda Mezabarba Raggazzi, Walter Gomes da Silva Filho, Fernanda Moura Vargas Dias, Fernando Zanela da Silva Arêas   +6 more
doaj   +1 more source

Estimates of persistent inward current in human motor neurons during postural sway [PDF]

, 2015
Persistent inward current (PIC) is a membrane property critical for increasing gain of motor neuron output. In humans, most estimates of PIC are made from plantarflexor or dorsiflexor motor units with the participant in a seated position with the knee ...
Foley, Ryan, Kalmar, Jayne M, Dr.
core   +1 more source

Stimulus - response curves of a neuronal model for noisy subthreshold oscillations and related spike generation

, 2005
We investigate the stimulus-dependent tuning properties of a noisy ionic conductance model for intrinsic subthreshold oscillations in membrane potential and associated spike generation.
A. Alonso, A. Longtin, B. Hille, C. N. Liu, C. N. Liu, D. Desmaisons, D. Pare, H. A. Braun, H. C. Pape, H. C. Tuckwell, Hans Albert Braun, I. Lampl, J. A. White, M. T. Huber, Martin Tobias Huber, N. Ho, R. Amir, R. Amir, R. Klink, R. Llinas, W. C. Stacey, X. J. Wang, Y. Gutfreund, Y. Shu   +23 more
core   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Educating the next generation of psychiatrists in the use of clinical neuromodulation therapies: what should all psychiatry residents know?

Frontiers in Psychiatry
A variety of neuromodulation treatments are available today and more are on the way, but are tomorrow’s psychiatrists prepared to incorporate these tools into their patients’ care plans?
Sahit N. Menon, Tyler Torrico, Bruce Luber, Brian Gindoff, Lisa Cullins, William Regenold, Sarah H. Lisanby   +6 more
doaj   +1 more source