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OPTOGENETIC NEUROMODULATION

Neurosurgery, 2009
Modulation of the nervous system by electrical or chemical means (neuromodulation) is becoming increasingly sophisticated, with application to a growing number of neurological diseases. However, both chemical and electrical neuromodulation are limited in their specificity.
Jaimie M, Henderson   +2 more
openaire   +2 more sources

Neuromodulation for Epilepsy

Neurosurgery Clinics of North America, 2016
Several palliative neuromodulation treatment modalities are currently available for adjunctive use in the treatment of medically intractable epilepsy. Over the past decades, a variety of different central and peripheral nervous system sites have been identified, clinically and experimentally, as potential targets for chronic, nonresponsive therapeutic ...
Vibhor, Krishna   +4 more
openaire   +2 more sources

Chemokines and neuromodulation

Journal of Neuroimmunology, 2008
Chemokines are not only mediators of the immune system and expressed in inflammatory situations. They are also constitutively expressed in the brain in both glial cells and neurons. Several recent evidence suggest that they can have a neurotransmitter/neuromodulatory role on brain functions similar to several neuropeptides reported so far.
Stéphane, Mélik-Parsadaniantz   +1 more
openaire   +2 more sources

Neurophysiology and neuromodulators

Neurological Sciences, 2007
Migraine is an episodic brain disorder that results in significant morbidity. Antiepileptic drugs (neuromodulators) are increasingly recommended for migraine prevention because of placebo-controlled double-blind trials that prove them effective. Cortical spreading depression (CSD) is thought to be the pathophysiological correlate of the neurological ...
M, Aguggia, G, D'Andrea, G, Bussone
openaire   +2 more sources

Optogenetic Neuromodulation

2012
The recent development of optogenetics, a revolutionary research tool in neuroscience, portends an evolution of current clinical neuromodulation tools. A form of gene therapy, optogenetics makes possible highly precise spatial and temporal control of specific neuronal populations.
Paul S A, Kalanithi, Jaimie M, Henderson
openaire   +2 more sources

Neuromodulators in Men

Dermatologic Surgery
BACKGROUND AND OBJECTIVE Botulinum toxin treatment is gaining popularity among men for cosmetic purposes driven by workplace competition and a desire for confidence and youthfulness. Because of the unique features of male facial anatomy, careful consideration is necessary during assessment and treatment execution.
Ardalan, Minokadeh   +2 more
openaire   +2 more sources

Neuromodulation in Epilepsy

Neurosurgery, 2011
Neuromodulation strategies have been proposed to treat a variety of neurological disorders, including medication-resistant epilepsy. Electrical stimulation of both central and peripheral nervous systems has emerged as a possible alternative for patients who are not deemed to be good candidates for resective procedures.
Faisal A, Al-Otaibi   +2 more
openaire   +2 more sources

Percutaneous neuromodulation

Urologic Clinics of North America, 2005
Neuromodulation for pelvic floor dysfunction has evolved from central sacral stimulation, a relatively invasive, experimental procedure, to percutaneous peripheral neurostimulation, which is both minimally invasive and well-tolerated by patients. Multiple series have now reported consistent positive results for varied manifestations of pelvic floor ...
Matthew R, Cooperberg   +1 more
openaire   +2 more sources

Magnetoencephalography and Neuromodulation

2012
Magnetoencephalography (MEG) is a noninvasive method which allows recordings of human brain activity with excellent temporal and good spatial resolution. In this chapter, we review applications of MEG in neuromodulation. We provide an overview of studies which used MEG to optimize parameters for neuromodulation and to characterize the ...
Alfons, Schnitzler, Jan, Hirschmann
openaire   +2 more sources

Ultrasonic neuromodulation

Journal of Neural Engineering, 2016
Ultrasonic waves can be non-invasively steered and focused into mm-scale regions across the human body and brain, and their application in generating controlled artificial modulation of neuronal activity could therefore potentially have profound implications for neural science and engineering.
Omer, Naor, Steve, Krupa, Shy, Shoham
openaire   +2 more sources

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